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All Journal Medula Jurnal Biologi Tropis Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran
Nisa Karima
universitas lampung
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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MINYAK NABATI SEBAGAI PENGGANTI BAHAN KIMIA TOKSIK PADA PROSES CLEARING JARINGAN HISTOPATOLOGI Balqis Mezzaluna D'Azzuri; Susianti Susianti; Nisa Karima
Medula Vol 13 No 6 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i6.813

Abstract

The clearing stage is an important step in preparing tissue histology to be examined under a light microscope, clearing is done to clean the tissue so that it is possible to insert it with an embedding material. Xylene is the material most widely used because of its excellent compatibility with fixing materials such as alcohol and paraffin. However, xylene is known to have various toxic effects on the exposed body. Many alternative materials have been found to replace xylene as a clearing agent in the process of making histopathological tissues. These ingredients are vegetable oils including coconut oil, peanut oil, olive oil, palm oil, and corn oil. These materials can be used as clearing agents without affecting the histological tissue composition, are more affordable, and do not cause health problems.
Analysis of Antibacterial Test and Brine Shrimp Lethality Test from Extract Sponge Derived Fungi Oktora Susanti; Nisa Karima; Ervina Damayanti
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): Juli - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12101

Abstract

Bacterial resistance to antibiotics has increased the demand for new antibacterial agents from natural sources, including marine organisms. This study evaluated the antibacterial activity and toxicity of sponge-associated fungal extracts. Antibacterial activity against Escherichia coli was tested using the disc diffusion method, while toxicity was assessed using the Brine Shrimp Lethality Test (BSLT). The extract was obtained by maceration with 95% methanol and tested at various concentrations. The extract showed antibacterial activity, with the largest inhibition zones at 100 and 1,000 ppm after 24 hours, which decreased after 48 hours. BSLT results showed 100% mortality of Artemia salina larvae at concentrations ≥100 ppm. The main BSLT test revealed a dose–response relationship, with higher doses and longer exposure reducing larval survival. These results indicate that sponge- associated fungal extracts are promising antibacterial agents, although their toxicity requires further evaluation.
Efektivitas Metode McKenzie dalam Mengurangi Intensitas Nyeri terhadap Low Back Pain: Literature Review Ghistavera Izvantia; Ahmad Fauzi; Nisa Karima; Dyah Wulan Sumekar Rengganis Wardani
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 3 No. 1 (2025): Januari : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v3i1.4704

Abstract

Low Back Pain is a degenerative disease that causes pain or discomfort in the 5th lumbar vertebra to the 1st sarcosacral vertebra. Low Back Pain itself is still one of the top five conditions that cause state losses in the world because it causes disability in sufferers. Non-pharmacological therapy for low back pain is McKenzie therapy. This study aims to see the effectiveness of McKenzie therapy in low back pain sufferers by searching the literature through the PubMed website, Google Scholar, Cochrane, and other scientific journal websites with the keyword "effectiveness of McKenzie methods for Low Back Pain". The results of the analysis show that McKenzie therapy is effective in reducing pain in low back pain sufferers. Further studies are needed to see the long-term effects, comparison of McKenzie therapy with other therapies, and combination of therapies to reduce pain intensity in low back pain sufferers.  
Co-Authors Ahmad Fauzi Balqis Mezzaluna D'Azzuri Dyah Wulan Sumekar Rengganis Wardani Ervina Damayanti Ghistavera Izvantia Oktora Susanti Susianti Susianti