Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Analit: Analytical and Environmental Chemistry
Mellinda Mellinda
Unknown Affiliation
Chemical Engineering, Chemistry & Bioengineering Chemistry

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
PENGEMBANGAN ANALISA GLIBENKLMID MENGGUNAKAN SORBEN POLIMER BERCETAKAN MOLEKUL Lasmaryna Sirumapea; Herlina Herlina; Hilma Hilma; Mellinda Mellinda
Analit: Analytical and Environmental Chemistry Vol 8, No 2 (2023): ANALIT: ANALYTICAL AND ENVIRONMENTAL CHEMISTRY
Publisher : Universitas Lampung Jl. Prof. Dr. Sumatri Brojonegoro No.1 Bandar Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/aec.v8i2.2023.p24-33

Abstract

Research on the development of glibenclamide analysis has been carried out using molecularly printed polymeric sorbents. This study aims to prepare a selective and accurate method of determining glibenclamide, through the molecular imprint method. Glibenclamide imprinted polymers have been successfully synthesized. Methyl methacrylic acid, ethyleneglycodimethacrylate, benzoyl peroxide were dissolved in acetonitrile and chloroform at a controlled temperature of 70°C. Extraction was carried out with methanol: acetic acid (8.5:1.5). Physical functional group analysis was carried out with FTIR spectrophotometer which showed specific peaks of glibenclamide, amine and amide groups at 3405 cm-1. The selectivity test gave the following results: imprinting factor (IF) = 2.45 and the selectivity coefficient (λ) for ramipril = 1.21 and against metformin = 2.28. The results showed that the polymer had a good impression and was selective for glibenclamide analysis Keywords: glibenklamid, molecularly imprinted polymer, metformin, ramipril.
Co-Authors Herlina Herlina Hilma Hilma Lasmaryna Sirumapea