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Variasi Jenis Diluent Terhadap Mutu Fisik Tablet Temu Putih (Curcuma Zedoaria) menggunakan Metode Cetak Langsung iswandi iswandi; Pudiastuti
Jurnal Farmasi Indonesia AFAMEDIS Vol. 4 No. 2 (2023): AFAMEDIS || JURNAL FARMASI INDONESIA
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

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Abstract

Abstract White Tumeric (Curcuma zedoaria) is a plant that contains curcuminoid compounds and essential oils on its rhizomes which are useful as anticancer. The purpose of this study is to find out which type of filling material (diluent) is good as a filler for white meeting tablets (Curcuma zedoaria). Tablets are made using the direct printing method with the types of fillers (diluent) used are ludipress, starch 1500, and Spray Dried Lactose. The resulting tablets were carried out still angle and flow properties tests, compression index tests, weight uniformity tests, size uniformity tests, tablet hardness tests, tablet brittleness tests, and crush time tests. In the test of stationary angle and flow properties and compression index in ludipress filler materials, the flow property value was 10.42 g/s, the stationary angle value was 27.77º, and the compression index was 10%. In the starch filler material 1500 obtained a flow property value of 4.17 g / s, a stationary angle of 34.40º, and a compression index of 30%, in the formulation of Spray Dried Lactose obtained a flow property value of 10.18 g/s, a stationary angle of 27.74º, and a compression index of 5%. Variations of the type of diluent Spray Dried Lactose show optimal results for white temu tablet filler (Curcuma zedoaria).
Co-Authors Iswandi Iswandi