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All Journal Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Buana Farma
Eko Sri Wahyuningsih
Fakultas Farmasi, Universitas Buana Perjuangan Karawang, Jawa Barat, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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REVIEW ARTIKEL : TELAAH PENGOBATAN MODERN GOLONGAN DIURETIK DENGAN TANAMAN HERBALNYA Indah Sari Amanatun Nisa Indah; Eko Sri Wahyuningsih; Neni Sri Gunarti
Jurnal Buana Farma Vol. 3 No. 3 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i3.869

Abstract

Hypertension is one of the most common diseases in adults and a risk factor for cardiovascular disease. Hypertension can be said to be a "silent killer" because the patient does not show symptoms before reaching a serious condition or even complications or even death. Hypertension can be treated using 5 classes, namely diuretics, angiotensin converting enzyme inhibitors (ACE Inhibitors), calcium channel blockers (CCB), beta blockers (β Blockers), angiotensinreceptor blockers (ARBs). The aim of this article was to review to find out the types of herbal plants used Has diuretic activity in hypertension. Data search was carried out using Google Scholar and PubMed. Using the keyword "hypertensive diuretic herbal plants". The sources or references obtained are journals from the last 10 years. The results obtained show that there are several herbal plants that have diuretic activity in hypertension, including cucumber (Cucumis sativus L), rosella flowers (Hibiscus sbadariffa), cloves (Syzygium aromaticum L.), tin leaves (Ficus carica L), cat's whiskers (Ortosiphon aristatus), Tomato (Solanum lycipersicum), Celery leaves (Apium graveolens), Soursop (Annona muricata L), Belimbing Wuluh (Averrhoa bilimbi L.), in some of these herbal plants there are chemical compounds that affect the diuretic process and can reduce blood pressure blood, namely Potassium which works by increasing the secretion of sodium, water and chlorine by reducing the volume of blood and extracellular fluid, and the test or method that is carried out can be made in the form of tea, juice, and can be boiled, then drunk the boiled water.
UJI AKTIVITAS ANTIBAKTERI FACE MIST EKSTRAK ETANOL DAUN ANDONG MERAH (Cordyline fruticosa (L) A. Chev.) TERHADAP Propionibacterium acnes Eko Sri Wahyuningsih; Melisa Puspitasari; Neni Sri Gunarti; Maulana Yusuf Alkandahri
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 8 No 2 (2023): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v8i2.5907

Abstract

This research is motivated by the problem of skin infection in the form of acne, one of the causes of which is the bacterium Propionibacterium acnes. Red andong leaves contain several secondary metabolites that have the potential as antibacterials such as flavonoids, tannin, saponins,and polyphenolic. The purpose of this study was to make a face mist preparation formula from red andong leaf extract which has the potential as an antibacterial for Propionibacterium acnes. The extraction method used was maceration with 70% ethanol solvent. Testing the inhibition of antibacterial activity was carried out using the well-diffusion method. Determination of the concentration of the extract needed for face mist preparation is taken from the results of the MIC test. Face mist preparations were made with 3 concentrations, namely formulas F3.12, F6.25, and F9.37. The face mist base was used as a negative control and the face mist base added with clindamycin powder was used as a positive control. Testing the face mist of red andong leaves extract included organoleptic, homogeneity, specific gravity, pH, spray spreadability, dry time, and hedonic tests. The results showed that the face mist of the ethanol extract of red andong leaves extract met the requirements for a good face mist preparation and had an inhibitory effect on the growth of Propionibacterium acnes bacteria in all formulas. Face mist Formulation 3.12% has an inhibition of 8.19 ± 0.22 mm, Formulation 6.25% has an inhibition of 10.59 ± 0.13 mm, and Formulation 9.37% has an inhibition of 11.75 ± 0.17 mm. From this study, it can be concluded that face mist containing 9.37% (F9.37) of red andong leaf extract was the most effective formulation against Propionibacterium acnes bacteria with the highest inhibition zone diameter of 11.75 ± 0.17 mm.
LITERATUR RIVIEW : TELAAH PENGOBATAN MODERN DAN TRADISONAL PADA PENYAKIT ASAM URAT (GOUT) Siska Ratna Dewi; Eko Sri Wahyuningsih; Neni Sri Gunarti
Jurnal Buana Farma Vol. 3 No. 4 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i4.870

Abstract

Metabolic disorders are disorders that increase uric acid levels (hyperurasemia). This disease is often found both in Indonesia and other countries on the Asian continent. Xantahuine Oxidase Inhibitor class drugs such as allopurinol and febuxostat are recommended as the first line of treatment, but it should be noted that continuous use of Xantahunine Oxidase Inhibitors can cause side effects of toxicity in the digestive system and increase acute attacks of gout at the start of therapy. Therefore, many studies involving many herbal plants are expected to have antihyperuricemia activity because herbal plants have a lower risk of toxicity and side effects. Based on research that has been carried out, Red Ginger (Zingiber officinale var. Amarum), Bay Leaves (Syzygium polyanthum), Seruhan Herb (Peperomia pellucida (L.) Kunth, Meniran (Phyllanthus niruri Linn.), Bamboo Shoot Extract (Schizostachyum brachycladum Kurz), Wood Secang (Caesalpinia sappan L.), Tangkur Fern (Polypodium feei), White Dragon (Hylocereus undatus), Malu Princess Plant (Mimosa pudica L.), Soursop Leaves (Annona muricata L.), Sparattosperma Leucanthum, Mahkota Dewa (Phaleria macrocarpa ( Scheff.) Boerl.), Mangosteen Fruit Peel (Garcinia mangostana L.), Dioscorea tokoro Makino, Chatupatika have antihyperuricemia activity. Therefore, in this review the antihyperuricemia activity of fifteen of these plants will be discussed. The results obtained from several articles are Some of these plants have antihyperuricemia properties through xanthine oxidase inhibition tests and reduce uric acid levels in test animals, so they have the potential to be developed as drugs for hyperuricemia
FORMULASI DAN UJI ANTIBAKTERI SABUN MANDI PADAT EKSTRAK ETANOL DAUN JAMBLANG (Syzygium cumini (L) Skeels) TERHADAP Staphylococcus aureus Himyatul Hidayah; Eko Sri Wahyuningsih; Surya Amal; Ananda Kamila
Jurnal Buana Farma Vol. 3 No. 4 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v3i4.894

Abstract

Staphylococcus aureus bacteria is one of the microorganisms that cause infectious diseases of the skin. Jamblang leaves (Syzygium cumini (L) Skeels) contain bioactive compounds with antibacterial potential such as alkoloids, flavonoids, saponins, steroids, and tannins. The purpose of this study was to analyze the antibacterial activity of extracts and solid soap preparations from ethanol extracts of jamblang leaves that have potential as antibacterial Staphylococcus aureus. Method: jamblang leaf simplisia powder was macerated with 70% ethanol solvent, thick extract of jamblang leaf was tested for antibacterial activity inhibition using disc diffusion method. Solid soap preparations were made with three concentrations of jamblang leaf extract addition, namely F1 (5%), F2 (6.25%) and F3 (7.5%). The results showed that the solid soap of 70% ethanol extract of jamblang leaves can inhibit Staphylococcus aureus bacteria at all three concentrations. Formulation 1 (5%) solid soap has an inhibition zone of 6.93mm ± 0.85, Formulation 2 (6.25%) 8.61mm ± 0.99 and Formulation 3 (7.5%) 11.2mm ± 1.90. This study can be concluded that the three formulations can inhibit Staphylococcus aureus bacteria.
Co-Authors Ananda Kamila Gunarti, Neni Sri Himyatul Hidayah Indah Sari Amanatun Nisa Indah Maulana Yusuf Alkandahri Melisa Puspitasari Siska Ratna Dewi Surya Amal