Muhammad Farid Hasyim
Jurusan Farmasi Politeknik Sandi Karsa

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Leaf Identification Test of Kakatuk (Sauropus androgunus (L) Merr) Cytotoxic On Inhibition of Cell Mitosis Sea urchin (Tripneustes gratilla Linn.) Muhammad Farid Hasyim; Martono Kalape Ngkedo
Jurnal Farmasi Sandi Karsa Vol 7 No 2 (2021): Jurnas Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v7i2.87

Abstract

Cancer, which is a dangerous disease, it does not mean that it cannot be cured. For now, cancer treatment is done with chemotherapy, surgery and some of them with oral drugs, but they are expensive and have not been able to cure most cancer sufferers. Plants that are often used as traditional medicine are katuk plants. Katuk plant (Sauropus androgunus (L) Merr) has many benefits in everyday life such as facilitating breast milk, treating ulcers, ulcers and treating dirty blood. The aim of this study was to test the identification of cytotoxic Katuk (Sauropus androgunus (L) Merr) leaves against the inhibition of mitosis of sea urchins (Tripneustes gratilla Linn.). The results of the study showed that the level of inhibition of cell division of the methanol fraction of katuk leaves against the antimitotic test of sea urchin eggs (T. gratilla) with IC50 = 147μg/ml. The methanol fraction of 1 katuk leaf had a greater toxic effect on Artemia salina Leach, with LC50 value = 353μg/ml. The methanol fraction 1 of katuk leaves had cytotoxic activity against Hela cancer cells which was greater than fraction 2 with an IC50 value of 305.941 g/ml in fraction 1 and 711.954 g/ml in fraction 2.
An Overview of Community Behavior Towards Self-Medication for Diarrhea Drugs in Risa Village, Woha District, Bima Regency Megawati Megawati; Muhammad Farid Hasyim; Marselina Sabu Ruron
Jurnal Farmasi Sandi Karsa Vol 9 No 1 (2023): Jurnal Farmasi Sandi Karsa (JFS)
Publisher : Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36060/jfs.v9i1.120

Abstract

Self-medication or self-medication is part of the community's efforts to treat minor ailments by using over-the-counter drugs, limited over-the-counter drugs and mandatory pharmacy drugs without consulting a doctor first. Diarrhea is a mild disease that can be treated with self-medication. The method used in this research is descriptive method, namely research that covers surveys with data collection techniques in the form of questionnaires. This research was conducted in Risa Village, Woha District, Bima Regency. This research was conducted in March 2023 using a questionnaire on 140 respondents according to the criteria. The results of this study indicate that the community's behavior towards diarrhea drug self-medication in Risa Village, Woha District, Bima Regency is classified as good with a percentage level of 95.13%.