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Description Of C-Reactive Protein (CRP) In Patients With Type 2 Diabetes Mellitus At Mulyorejo Health Center In Malang City Febriyanti Wora Kapero; Erni Yohani Mahtuti; Previta Zeizar Rahmawati
Jurnal Analis Medika Biosains (JAMBS) Vol 10, No 2 (2023): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v10i2.320

Abstract

Diabetes Mellitus Type 2 is a metabolic disorder condition characterized by hyperglycemia, due to decreased insulin secretion. Many cytokines play a role in the acute phase response, so that markers such as CRP increase in patients with type 2 DM. The type of research used in this study is descriptive research, which describes the results of CRP examination in patients with type 2 diabetes. Examination of respondents' serum C-Reactive Protein (CRP) levels was carried out qualitatively using the Latex Agglutination method and followed by a semi-quantitative method, namely dilution to determine the level of inflammation. The results of CRP examination on 30 serum samples that have been carried out on patients with Type 2 Diabetes Mellitus found that 29 (96.7%) were positive and 1 (3.3%) of respondents were negative. The group of CRP levels for titer 12 was 5 samples (16.7%), titer 24 was 17 samples (56.7%), titer 48 was 5 samples (16.7%), and titer 96 was 2 samples (6.7). %). The results of the four groups with the highest CRP levels, namely a titer of 24 mg/L as many as 17 samples (56.7%) showed that some of the CRP levels were higher than normal. Conclusion Almost all respondents with type 2 Diabetes Mellitus had positive C-Reactive Protein examination results and a small proportion of type 2 Diabetes Mellitus patients had negative C-Reactive Protein examination results. 
Gambaran Waktu Clearing Xylol dan Minyak Kayu Putih Terhadap Kualitas Preparat Awetan Ctenocephalides Canis Novi Yuniar; Faisal Faisal; Erni Yohani Mahtuti; Previta Zeizar Rahmawati
Quantum Wellness : Jurnal Ilmu Kesehatan Vol. 1 No. 4 (2024): Desember: Quantum Wellness : Jurnal Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/quwell.v1i4.1085

Abstract

Making durable preparations includes a fixation process using 10% KOH, dehydration, clearing and mounting. Clearing aims to make the morphological structure of a sample or object appear clearer, more transparent and clearer. In this research, the solution used was xylol solution and eucalyptus oil. Xylol is a solution that is not environmentally friendly, because it comes from petroleum or liquid asphalt. Meanwhile, eucalyptus oil is a solution obtained from the distillation of eucalyptus leaves which is environmentally friendly and easy to obtain and has non-polar properties which can remove residues in paraffin in preparations, so it can be used as a substitute for xylol. This research aims to describe the quality of preserved Ctenocephalides canis preparations in the clearing process using xylol and eucalyptus oil. The samples in this study were 24 adult Ctenocephalides canis. The results of the study showed that the durable preparations using xylol received 4 good preparations, 5 fairly good preparations, and 3 poor preparations. Meanwhile, the results of durable preparations using eucalyptus oil were 5 good preparations, 6 quite good preparations, and 1 bad preparation. So it can be concluded that making permanent preserved preparations for Ctenocephalides canis is better using eucalyptus oil compared to xylol.
RELATIONSHIP BETWEEN ALBUMIN LEVELS IN TYPE 2 DIABETES MELLITUS PATIENTS : HUBUNGAN KADAR ALBUMIN PADA PENDERITA DIABETES MELITUS TIPE 2 Yohani, Erni; Evania Melly Fera Mbeo; Previta Zeizar Rahmawati; Ariana Listuhayu Wahyuni
Journal of Nursing Care and Biomolecular Vol 10 No 1 (2025): Journal of Nursing Care and Biomolecular
Publisher : STIKes Maharani Malang

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Abstract

Introduction: Diabetes Mellitus is a metabolic disorder characterized by insulin resistance.The state of diabetes affects the metabolism of proteins in the body, one of which is albumin This study aims to determine the relationship between Albumin Levels in Type 2 Diabetes Mellitus Patients at Prasetya Husada Hospital. Methods: quantitative descriptive with a sample of all medical record data as many as 70 patients. Results: relationship between the value of albumin levels and the severity of diabetics Analysis: a significant correlation between albumin levels and the severityof diabetes mellitus, the relationship between these two variables is negative with the degree of relationship that is moderate correlation. (p< 0.00; r = - 0.506). Discussion: The Albumin levels in Diabetes Mellitus sufferers are described based on age, length of diagnosis, and severity, obtaining significant results between the severity of Diabetes Mellitus and the Albumin levels which are correlated or related.
Gambaran Hasil Pemeriksaan Benzodiazepine Pada Pasien Gagal Ginjal Kronik Yang Menjalani Hemodialisa Di RS Karsa Husada Batu Mela Tri Mayang Sari; Previta Zeizar Rahmawati
Journal of Medical Laboratory and Science Vol 5 No 2 (2025): JMLS: Journal of Medical Laboratory and Science
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/medlabscience.v5i2.2953

Abstract

Latar Belakang: Pasien gagal ginjal kronik (GGK) dengan hemodialisa sering mengalami gangguan psikososial, di antaranya kecemasan serta kualitas tidur buruk akibat perubahan fisik dan keterbatasan aktivitas. Penggunaan obat benzodiazepine digunakan untuk mengatasi gangguan tersebut, karena memiliki efek sedatif pada sistem saraf pusat. Namun, dalam penggunaan obat benzodiazepine tidak lepas dari efek samping seperti pusing, kelelahan, serta resiko ketergantungan, terutama penggunaan jangka panjang. Tujuan penelitian ini untuk mengetahui gambaran hasil pemeriksaan benzodiazepine pada pasien gagal ginjal kronik yang menjalani hemodialisa di RS Karsa Husada Batu. Metode: Penelitiaan ini merupakan penelitian deskriptif kualitatif. Sampel penelitian berjumlah 20 urine pasien gagal ginjal kronik yang menjalani hemodialisa di RS Karsa Husada Batu. Pemeriksaan penelitian ini menggunakan alat strip-test benzodiazepine yang merupakan salah satu metode uji skrining yang digunakan secara umum, cepat, dan relatif murah. Hasil negatif ditandai dengan dua garis warna merah pada kolom test dan kontrol, sedangkan hasil positif ditandai satu garis warna merah pada kolom kontrol. Hasil: Pada penelitian ini pada parameter kecemasan menunjukkan hasil bahwa seluruh responden yaitu 20 responden (100%) mengalami gangguan kecemasan. Berdasarkan parameter kualitas tidur, diperoleh 7 responden (35%) mempunyai kualitas tidur baik, sementara yang mempunyai kualitas tidur buruk ada 13 responden (65%). Hasil dari pemeriksaan benzodiazepine didapatkan 18 responden (90%) negatif dan 2 responden (10%) positif kandungan benzodiazepine. Kesimpulan: Berdasarkan hasil pemeriksaan terhadap 20 sampel urine pada pasien gagal ginjal kronik yang menjalani hemodialisa di temukan bahwa dari 20 sampel urine menunjukkan hasil negatif 18 responden (90%), dan hasil positif didapatkan 2 responden (10%) terhadap kandungan benzodiazepine. Kata kunci : Benzodiazepine, Gagal Ginjal Kronik, , Kecemasan, Kualitas Tidur
Hubungan Titer Widal Dengan Limfosit Dan Trombosit Pasien Demam Tifoid Di Puskesmas Geovani R Lubu Pati; Previta Zeizar Rahmawati
Media Husada Journal Of Nursing Science Vol. 7 No. 2 (2026): Juli
Publisher : STIKES Widyagama Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33475/mhjns.v7i2.941

Abstract

Background: Typhoid fever is a systemic infection caused by Salmonella typhi that leads to hematological abnormalities, including thrombocytopenia and relative lymphocytosis, due to the effects of endotoxins on bone marrow. The Widal test is still widely used as a serological examination in primary health care; however, the correlation between Widal titer and hematological parameters remains inconsistent. Objective: To analyze the correlation between Widal antibody titer and lymphocyte and platelet counts in patients with typhoid fever at Puskesmas. Methods: This was a retrospective cross-sectional analytical observational design. Data were obtained from the medical records of typhoid fever patients at Puskesmas Dau from January to December 2024. Samples were selected using purposive sampling based on inclusion criteria: patients with typhoid fever who had results for Widal titers O, H, PA, PB, lymphocyte and platelet count, and complete medical records. Exclusion criteria included patients with other diagnoses, such as dengue fever and incomplete data. Data analysis was performed using Spearman’s Rank Correlation test with a significance level of p < 0.05. Results: The results showed no significant correlation between Widal titer and lymphocyte count, but a significant negative correlation between Widal titer and platelet count, with r = -0.146 and p = 0.039 [p < 0.05]. This indicates that higher the Widal titer, the lower the platelet count tends to be. Conclusion: There is no correlation between Widal titer and lymphocyte count. There is a significant but very weak negative correlation between Widal titer and platelet count in typhoid fever. These findings are consistent with the pathophysiology of typhoid fever, specifically thrombocytopenia resulting from the effect of S. Typhien dotoxin on bone marrow.