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All Journal International Journal of Health, Economics, and Social Sciences (IJHESS)
Dhea Ivanka
Faculty of Medicine, Palangka Raya University, Indonesia
Economics, Econometrics & Finance Public Health Social Sciences

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A Literature Review: Understanding TNF and IL-1 of the Main Cause of Thorombo-occlusive in Lucio’s Phenomenon Erald Giovanny Hasiholan Simatupang; Ulfa Pratiwi; Hayuningrat Odyssey Saint; Dhea Ivanka
International Journal of Health, Economics, and Social Sciences (IJHESS) Vol. 5 No. 4: October 2023 - International Journal of Health, Economics, and Social Sciences (IJHESS
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/ijhess.v5i4.4259

Abstract

Last year, it was 0.5 out of every 10,000 people, but now it has increased. Lucio's Leprosy, also known as Leprosy Bonita, is a very uncommon type of serious leprosy. The Lucio phenomenon is a severe reaction that can occur in individuals with Lucio's leprosy. It causes a skin condition called "necrotizing erythema". This study used reliable and important scientific databases like PubMed, ScienceDirect, Google Scholar, as well as official databases from health organizations. These reactions occur in the cells of body's immune system, specifically the T helper 1 cells, in response to antigens from mycobacteria. Research has shown that certain substances produced by Th1 cells, such as IL-1?, TNF-?, IL-2, and IFN-?, are very important. High amounts of TNF-?, soluble IL-2 receptors, and adhesion molecules show how serious the local inflammation is. Patients with a mild form of leprosy who are experiencing a specific type of immune response have higher levels of a molecule called TNF-? in their nerves and skin. Type 1 reactions are caused by certain types of immune cells called Th1 lymphocytes. The WHO said it's important to make sure patients and communities know about leprosy so they can get help on their own. They think this is a very important part of their plan to fight leprosy worldwide.
Exploring Echinococcus Infection in the Spinal Cord: Clinical Manifestations and Management Insight Erald Giovanny Hasiholan Simatupang; Dhea Ivanka
International Journal of Health, Economics, and Social Sciences (IJHESS) Vol. 6 No. 2: April 2024 - International Journal of Health, Economics, and Social Sciences (IJHESS)
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/ijhess.v6i2.3848

Abstract

Echinococcus infection in the spinal cord can lead to various complications, including compression of the spinal cord. In some cases, Echinococcus infection can result in the formation of dumbbell structures within the spinal cord, extending into the paravertebral region. This type of infection is characterized by a high recurrence rate, ranging from 50% to 100%. This study used reliable and important scientific databases like PubMed, ScienceDirect, Google Scholar, as well as official databases from health organizations. Furthermore, studies have shown that individuals with preexisting conditions like pressure ulcers are at an elevated risk of postoperative infections following spinal cord surgery. Echinococcus infection in the spinal cord can have serious consequences such as compression and the formation of complex structures. Understanding the risk factors associated with postoperative infections and the persistence of viral infections in the spinal cord is crucial for effective management and treatment strategies in affected individuals.
Co-Authors Erald Giovanny Hasiholan Simatupang Erald Giovanny Hasiholan Simatupang Hayuningrat Odyssey Saint Ulfa Pratiwi