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All Journal Jurnal Armada Informatika Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute HJSE
Raudhah
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Education Health Professions Medicine & Pharmacology Neuroscience Physics Public Health

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Gluxsystem: Real-Time Monitoring of Diabetic Wounds Using an App-Iot Integrated Hydrogel Patch Azizah Nur Sya'bani; Dea Ocha Nerissa Arviana; Raudhah
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 9 No. - (2025): Proceedings Book of International Conference and Exhibition on The Indonesian M
Publisher : Writing Center IMERI FMUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69951/proceedingsbookoficeonimeri.v9i-.324

Abstract

Introduction: Diabetes mellitus is a metabolic disorder associated with severe complications, including diabetic foot ulcers (DFU). The World Health Organization estimates that more than 830 million people worldwide are affected. DFU remains a leading cause of infection, amputation, and mortality, largely due to delayed detection of changes in the wound microenvironment. Objective: This study presents a theoretical design and conceptual framework for GLUXSYSTEM, an intelligent hydrogel-based patch integrating pH and glucose sensing with an application–IoT platform for non-invasive monitoring of diabetic wounds. Methods: The proposed sensing mechanisms are derived from established biochemical principles. pH sensing is conceptualized using a chitosan hydrogel containing glycerol and Bromothymol Blue (BTB), in which colorimetric changes result from pH-dependent protonation of the indicator. Glucose sensing is modeled using a PEGDA–APBA hydrogel embedded in a photonic crystal, in which glucose binding induces hydrogel swelling and structural color shifts. The system architecture envisions optical signal capture via a smartphone application for cloud-based data interpretation. Results: As a design-based study, the system is projected to produce distinguishable colorimetric responses corresponding to wound conditions. Based on the underlying chemical models, pH changes from acidic to alkaline would generate yellow-to-blue transitions, while increasing glucose concentration would produce structural color shifts from blue to purple and pink. These theoretical responses are consistent with reported associations between elevated pH/glucose levels and DFU severity. Conclusion: GLUXSYSTEM offers a conceptual, non-invasive approach to wound monitoring. While this study focuses on the design and integration framework, it provides a necessary foundation for future experimental validation and the development of accessible digital solutions in diabetic wound care.
Co-Authors Alasi, Tomy Satria Arbiatussaddiyah Rambe Azizah Nur Sya'bani Dea Ocha Nerissa Arviana Halimin M. Yogi Riyantama Isjoni Muhammad Luthfi Rizki Nomi Sinulingga Rangkuti, Ali Musa Riki Wanto Sahara Abdy Sri Ramadhany Yusril Mahendra