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Serum Creatinine and Cystatin-C Levels in Patients Diagnosed with Kidney Disorders Nurmeily Rachmawati; Yuliani Yuliani; Citra Trisna; Syarah Anliza; Ahmad Yani
Journal of Noncommunicable Diseases Prevention and Control Vol. 1 No. 2 (2023): Journal of Noncommunicable Diseases Prevention and Control
Publisher : Hypertension Prevention and Control Research Center, The Polytechnic of Health of Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61843/jondpac.v1i2.631

Abstract

The development of non-communicable diseases still dominates in Indonesia. One of them is kidney failure, which contributes to the burden of disease in the world with a fairly high death rate. Examination parameters to indicate renal condition can be seen from several laboratory examination results, such as levels of creatinine, urea, cystatin-C, uric acid, microalbuminuria, and others. The aim of this study is to obtain a brief overview of creatinine and cystatin-C levels in patients diagnosed with kidney disorders to determine the extent of the severity of the disease that has occurred. The method used in this research is descriptive analysis with laboratory examination using a cross-sectional approach. The number of samples in this research was 30. Based on the research results, respondents were dominated by women (53.3%) with an age range of 28–76 years. The proportion of respondents' creatinine levels was still more in the normal category, and the proportion exceeding the normal limit for male and female respondent groups was the same, namely 50% each. Meanwhile, the cystatin-C levels of respondents were more often found in the above-normal category (63.3%), which was dominated by the group of female respondents (57.9%).
Calcium Profile of Chronic Kidney Disease Patients Undergoing Hemodialysis Ahmad Yani; Desiana Wahyu Kuswardani; Citra Trisna; Venny Patricia
Journal of Noncommunicable Diseases Prevention and Control Vol. 2 No. 1 (2024): Journal of Noncommunicable Diseases Prevention and Control
Publisher : Hypertension Prevention and Control Research Center, The Polytechnic of Health of Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61843/jondpac.v2i1.713

Abstract

Chronic kidney disease (CKD) is a condition of progressive kidney deterioration, which is characterized by a decrease in the estimated glomerular filtration rate that lasts for more than three months. One of the therapies needed to maintain the quality of life of CKD sufferers is hemodialysis. One of the functions of hemodialysis is to regulate electrolyte levels in the blood, including calcium. Low calcium levels in the blood (hypocalcemia) can trigger the release of calcium minerals from the bones, which ultimately makes the bones brittle. So, it is essential to monitor the blood calcium levels of CKD sufferers so as not to worsen the sufferer's condition. This study used secondary data, and the research instrument used in this research was the patient's medical record. Sampling was carried out using the purposive sampling method. The inclusion criteria set were patients with CKD who underwent hemodialysis and had complete medical record data, including age, gender, length of time undergoing hemodialysis, and examination data in the form of blood calcium levels. The data included in this study came from 68 patients with CKD who underwent hemodialysis and had their blood calcium levels checked. Based on the research results, the prevalence of CKD was more significant in men (58.82%), and as many as 92.65% of the total respondents experienced hypocalcemia. Cases of hypocalcemia occurred more frequently in male patients (52.94%), in the 46-65 year age group (55.88%), and in patients who had undergone hemodialysis for 4-12 months (45.59%). Hypocalcemia sufferers need to pay attention to their nutritional intake to keep their blood calcium levels at a safe level.