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All Journal BAKIRA: Jurnal Pengabdian Kepada Masyarakat The Indonesian Journal of General Medicine
Vina Zakiah latuconsina
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Agriculture, Biological Sciences & Forestry Dentistry Health Professions Medicine & Pharmacology Public Health Veterinary Other

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PELATIHAN VIRTUAL PEMERIKSAAN PAP SMEAR Marlin Margareth Maelissa; Hadilah Rahawarin; Nathalie Elischeva Kailola; Vina Zakiah latuconsina
BAKIRA: Jurnal Pengabdian Kepada Masyarakat Vol 2 No 1 (2021): BAKIRA : Jurnal Pengabdian Kepada Masyarakat
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/bakira.2021.2.1.008-012

Abstract

Early detection through a screening program is one of the strategy to prevent cervical cancer that can help reduce cervical cancer morbidity and mortality. One of the method of early detection is through a pap smear evaluation. This workshop was held with the aim of increasing the knowledge of health workers, especially midwives, about pap smear evaluation. The activity was carried out online with a duration of five hours, the topics include Gynecological Procedures in the Pandemic Era of COVID19, Anatomy of the Female Reproductive System, Cervical Cancer and Pap smear Cytology presented by gynecologist and pathologist, followed by video streaming of cervical specimen collection methods for pap examination smear. Participants consisted of midwives as the main target, general practitioners, nurses, preclinical and clinical medical students, and midwifery students. The activity went well and smoothly, accompanied by discussions and sharing experiences about cervical cancer prevention services. There was an increase in knowledge from 39.42% to 68.33%. It is hoped that the knowledge gained from this activity can be applied in the services of health workers in their respective work areas so that it can help improve women's reproductive health and cervical cancer prevention.
Associations of The Gut Microbiota on Respiratory Disease in Children : A Systematic Review Indah Dwi Lestari; Rifah Zafarani Soumena; Vina Zakiah Latuconsina; Octovina Toressy; Rahma Dyahnissa
The Indonesian Journal of General Medicine Vol. 42 No. 1 (2026): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/jmpfne38

Abstract

Background: The gut-lung axis represents a critical pathway linking early-life gut microbiota to pediatric respiratory diseases, but comprehensive synthesis of associations, mechanisms, and therapeutic evidence is lacking. Methods: This systematic review synthesized 80 studies (RCT, etc) examining gut microbiota associations with pediatric respiratory outcomes including asthma, allergic rhinitis, respiratory tract infections (RTIs), bronchiolitis, bronchopulmonary dysplasia (BPD), and cystic fibrosis (CF) lung disease. Results: Early-life gut dysbiosis during the first 100 days—characterized by reduced Lachnospira, Veillonella , Faecalibacterium , Rothia (FLVR taxa)—consistently associated with increased asthma risk (Arrieta et al., 2015). Short-chain fatty acids (SCFAs), particularly acetate and butyrate, emerged as central immunomodulatory mediators (Yang et al., 2025). Mendelian randomization confirmed causal roles for Collinsella and Ruminococcaceae UCG014 in childhood asthma (Li et al., 2023). In CF, Bifidobacterium - dominant gut microbiota associated with 45% fewer pulmonary exacerbations (Ray et al., 2022). Probiotics reduced RTI incidence (42% vs 59% in controls) and acute asthma exacerbations (RR 0.38) but showed no benefit for primary asthma prevention. Cesarean delivery, antibiotic exposure (HR for asthma 1.21), and breastfeeding cessation were key moderators. Apparent diversity–disease contradictions resolved when considering community composition rather than diversity metrics alone. Conclusion: Gut microbiota composition in early life is causally associated with pediatric respiratory disease risk through SCFA-mediated immune modulation, with the first 100 days as a critical window. Probiotics show strain-specific efficacy for RTI prevention and asthma treatment but not primary prevention.
Co-Authors Hadilah Rahawarin Indah Dwi Lestari Marlin Margareth Maelissa Nathalie Elischeva Kailola Octovina Toressy Rahma Dyahnissa Rifah Zafarani Soumena