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All Journal INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks
Yesi Astri
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Computer Science & IT Health Professions Medicine & Pharmacology Social Sciences Other

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Upaya Pencegahan Stroke Hemoragik dan Penilaian Activity Daily Living (ADL) pada Pasien Pasca Stroke Yesi Astri; Trisnawati Mundijo; Isma Yulianti; Fadhilah Jasmine Shahab; Dhiya Ridha Shafira
Warta Pengabdian Andalas Vol 30 No 4 (2023)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.30.4.599-606.2023

Abstract

Stroke is one of the most common causes of mortality worldwide, and hypertension is a risk factor for stroke. The purpose of our activity is to increase the knowledge of stroke and hypertension in the community. This activity was conducted through counselling to 30 residents of RT 9, Kelurahan 14 Ulu, Seberang Ulu 2, Palembang, South Sumatera. Before and after counselling, a pretest and posttest were carried out to find out whether there was an effect of the counselling that had been given. In our conclusion, there are significant differences in knowledge about stroke and hypertension before and after counselling is given, with the average number of questions answered correctly by respondents from 5.06 to 6.30. Our study found that counselling activities and activity daily living assessments were able to increase knowledge and awareness of hypertension and stroke.
Spectroscopic characterization of rosella flower extract (Hibiscus sabdariffa L.) and its antibacterial activity against Enterobacter aerogenes in suspected typhoid cases Rohani, Siti; Martha, Fadhil Rizki; Mundijo, Trisnawati; Yesi Astri; Zilda, Malika; Melianti, Agnes
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 7 No 1 (2025): Advances in biomarkers, therapeutics, and probiotics: Recent updates in medical l
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v7i1.5577

Abstract

Typhoid, a serious bacterial disease, has spurred research into natural products like rosella (Hibiscus sabdariffa L.) for potential treatments. This study investigates the chemical components found in Rosella extract using spectroscopy approximation, assisted by Fourier transform infrared spectroscopy (FTIR) and Gas chromatography–mass spectrometry (GC–MS). The antibacterial activity of rosella extract on bacteria from stool cultures of suspected typhoid cases continues to be evaluated. The antibacterial experimental employed a post-test-only control group design, using 30 μg Chloramphenicol as a positive control, sterile distilled water as the negative control, rosella extract at concentrations of 25%, 50%, 75%, and 100% as the observed variable. Stool samples from typhoid patients were identified, and Enterobacter aerogenes were detected using VITEK®2 testing. Cultivated bacteria from the samples were tested to determine the antibacterial activity of the rosella extract. Phytochemical studies confirmed the presence of tannins, alkaloids, flavonoids, and saponins in the rosella extract. Additionally, the spectroscopic evaluation from FTIR and GC-MS showed the presence of chemical groups, including esters, aldehydes, and aromatics. Further clinical tests demonstrated antibacterial activity at the minimum inhibitory concentration. The results showed an increasing inhibition zone of bacterial growth, correlating with the increase in rosella extract concentration. Although the antibacterial activity of rosella extract was lower compared to commercial Chloramphenicol, this natural product has demonstrated antibacterial activity and shows potential as a candidate for future herbal medicine development.
Co-Authors Dhiya Ridha Shafira Fadhilah Jasmine Shahab Isma Yulianti Martha, Fadhil Rizki Melianti, Agnes Mundijo, Trisnawati Siti Rohani Trisnawati Mundijo Zilda, Malika