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Use of the “DNAChecker” Algorithm for Improving Bioinformatics Research Bhat, Nausheen; Wijaya, Ezra Bernadus; Parikesit, Arli Aditya
Makara Journal of Technology Vol. 23, No. 2
Publisher : UI Scholars Hub

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Abstract

Basic Local Alignment Sequencing Tool (BLAST) is a bioinformatics tool used for analyzing nucleotide sequences with regards to their similarity. BLAST can be found online on biological databases such as the National Center for Biotechnology Information (NCBI) and other such repositories. The mechanism of BLAST allows the target sequence to be compared with other sequences to find regions of local similarity, and thus, a comparability quotient that determines the resemblance between the sequences is created. Due to the open-platform nature of the online databanks, several sequences can be accepted with little to no interjections regarding the quality of sequence submitted. An example of unclean nucleotide sequences can be based on the number of non-template nucleotides, denoted as “N,” present within the sequence. Here we develop a self-established nucleotide sequence reading program known as “DNAChecker,” which helps identify the quality of the target sequence and therefore proposes the effectiveness of the BLAST result. DNAChecker is an inbuilt, program that runs on Python 3.4 and was implemented in the United States Agency for International Development (USAID) project conducted in Indonesia International Institute for Life Sciences. Although DNAChecker has proven to be useful, it has a lot of room for improvements, such as having a more objectively accurate means of differentiating between good and bad sequences.
ANALISA MENGENAI VARIASI STRENGTHENING EXERCISE DALAM PENANGANAN OSTEOARTHRITIS KNEE PADA LANSIA Tabita Widyasari; Ezra Bernandus Wijaya; Siswo Poerwanto
Binawan Student Journal Vol. 4 No. 2 (2022)
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Binawan (LPPM Universitas Binawan)

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Abstract

Osteoarthritis adalah penyakit kronik dan degeneratif yang ditandai dengan nyeri dan kerusakan kartilago sendi. OA lutut dikaitkan dengan keterbatasan mobilitas ekstremitas bawah sehingga menyebabkan gangguan keseimbangan dan gaya berjalan, sehingga mengurangi mobilitas dan fungsi pada pasien OA lutut. Latihan untuk meningkatkan kekuatan otot dan mobilitas sendi seringkali membutuhkan komitmen yang cukup besar dari pasien dalam jangka waktu yang lama. Penelitian ini bertujuan untuk mendeskripskikan beberapa literatur mengenai pengaruh variasi strengthening hip dan knee exercise pada penderita osteoarthritis knee dalam peningkatan fungsional. Sembilan literature dengan desain studi : Systematic Review/Meta-Analysis, Randomized Controlled Trial, Experimental Study,QuasiExperiment,Comparative Study, Cohort Study,Case Control Study, sampel Osteoarthritis Lutut, tahun publikasi 10 tahun terakhir (2011–2021), variabel yang diukur adalah peningkatan fungsional  dan kriteria eksklusi desain studi yang tidak relevan dan penelitian yang diterbitkan lebih dari 10 tahun. Hasil :  Didapatkan 9 literatur dari 4 data base menunjukan adanya peningkatan fungsional yang mempengaruhi nyeri pada pasien OA Knee. Dapat disimpulkan bahwa variasi exercise baik dan efektif adanya dalam penanganan Knee Osteoarthritis berdasarkan  9 (Sembilan)literatur yang di kaji mendapatkan hasil signifikan terhadap peningkatan fungsional, penurunan nyeri dan peningkatan kekuatan otot secara statistik atau bermakna dalam statistik.
Pengaruh Latihan Ladder Drills Two Feet Each Square Dan Ickey Shuffle Rahmawan, Rama Bayu; Wijaya, Ezra Bernadus
JOURNAL OF BAJA HEALTH SCIENCE Vol 4 No 01 (2024): Journal of Baja Health Science
Publisher : Universitas Banten Jaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47080/joubahs.v4i01.2856

Abstract

Salah satu elemen penting dalam pencak silat adalah adalah kecepatan. Khususnya dalam menyerang, lebih dari 75% serangan yang dipergunakan dalam pertandingan pencak silat adalah serangan dengan menggunakan teknik tendangan. Pada setiap pertandingan pencak silat, dapat dikatakan bahwa 100% pesilat menggunakan teknik ini dengan berbagai variasinya untuk mencari kemenangan. Tujuan : Untuk mengetahui apakah ada pengaruh dari latihan Ladder Drills Two Feet Each Square dan Ickey Shuffle terhadap peningkatan kecepatan pada tendangan sabit pencak silat di Padepokan Perisai Diri Gandul. Design study penelitian ini menggunakan quasi eksperimental one group pre test dan post test. Quasi Eksperimen menggunakan seluruh subjek dalam kelompok kecepatan untuk diberi perlakuan (treatment), bukan menggunakan subjek yang diambil secara acak. Dari hasil uji Independent T Test pada table diatas diperoleh hasil 0,001 bahwa Asymp. Sig. (2-tailed) <0,05. Hasil tersebut menunjukkan bahwa terdapat perbedaan atau pengaruh pada intervensi tersebut (Ha diterima). Maka dapat disimpulkan bahwa pemberian intervensi Ladder Drills Two Feet Each Square dan Ickey Shuffle dalam meningkatkan kecepatan tendangan sabit pada pesilat di Padepokan Pencak Silat Perisai Diri Gandul
PENGARUH LATIHAN PLYOMETRIC DOUBLE LEG SPEED HOP TERHADAP PENINGKATAN KECEPATAN BERENANG GAYA BEBAS PADA ATLET RENANG USIA 9 - 14 TAHUN Manda Mely Garitny; Ezra Bernadus Wijaya; Wahyuni, Deby Tri
Indonesian Journal of Physiotherapy Vol 3 No 1 (2023): Indonesian Journal of Physiotherapy
Publisher : Universitas Pembangunan Nasional Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52019/ijpt.v3i1.6202

Abstract

To swim required mastery of basic techniques. For example, sliding, moving the arms and legs, and taking a breath. The hallmark of freestyle is the whole body in a straight line. The movement of both arms is on the surface of the water. In the freestyle technique, many factors influence to be able to produce maximum swimming speed, including height, arm power and leg muscle strength. This research used a quasi experimental study. Quasi Experiments using the entire sample divided into two speed groups to be treated (treatment) and not given treatment (treatment), and using samples taken randomly. The research design uses Two Group Pre-Test Post-Test. the post-test results in the intervention group and the control group were 0.447 for the intervention group and 0.051 for the control group. The results of the normality test can be concluded that the P value is 0.05, where the resulting hypothesis is normally distributed data (Ho is accepted). In the control group, the result was 0.723. From the hypothesis results obtained, there was no difference or change in freestyle swimming speed for athletes at the Tirta Serayu Banjarnegara Club, so Ho was accepted and Ha was rejected. So it can be concluded that the intervention of Plyometric Double Leg Speed Hop is effective in increasing the speed of freestyle swimming in swimming athletes at the Tirta Serayu Banjarnegara Club.
Manfaat NMES dan Terapi Latihan untuk Kekuatan Quadriceps, LGS dan Fungsional Lutut Pasien Post TKR Success, Tazkiyatun Nisa Attaufiq Lulu Desara; Wijaya, Ezra Bernadus; Boroh, Zeth
Quantum Wellness : Jurnal Ilmu Kesehatan Vol. 2 No. 3 (2025): September : Quantum Wellness : Jurnal Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/quwell.v2i3.2250

Abstract

Postoperative Total Knee Replacement (TKR) patients often face various clinical problems, including quadriceps muscle weakness, limited range of motion of the knee joint, swelling, and pain that can have a significant impact on functional movement ability, independence of daily activities, and overall quality of life. The condition demands the role of the physiotherapist in providing appropriate and comprehensive interventions to facilitate the patient's recovery. One approach that can be done is to provide a combination of Neuromuscular Electrical Stimulation (NMES) modalities and exercise therapy. This study aims to evaluate the benefits of NMES and exercise therapy combination interventions in improving quadriceps muscle strength, knee joint range of motion, and functional mobility ability in post-TKR patients. The research design used a case study method involving three patients who were in phase 2 (motion phase), namely 3 days to 6 weeks after TKR surgery. Patients show complaints in the form of weakness of the quadriceps muscles, limited range of joint movement, and decreased knee function function. Physiotherapy interventions were given as many as 8 meeting sessions with a frequency of 2 times a week. The intervention program consisted of administering NMES to the quadriceps muscle and functional exercises such as sit to stand exercise, gait training, strengthening exercises using resistance bands in the ankle joint, and stair climbing. The results showed a significant increase in quadriceps muscle strength, an increase in the range of motion of the knee joint, and an improvement in functional movement ability after all intervention sessions were completed. These findings confirm that the combination of NMES with exercise therapy can be an effective rehabilitation strategy for post-TKR patients. The implementation of this method has the potential to speed up recovery, reduce dependence on others, and improve the patient's quality of life in a sustainable manner.