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Jekmal Malau
Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Singaperbangsa Karawang, Karawang, Jawa Barat, Indonesia.
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Potensi antibakteri ekstrak daun gendola (Basella alba Linn var. rubra) terhadap Escherichia coli dan Staphylococcus aureus Diah Muldianah; Marsah Rahmawati Utami; Jekmal Malau
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.308

Abstract

Gendola leaves (Basella alba Linn var. rubra) have long been utilized as an alternative treatment for various bacterial infections. This study aims to evaluate and determine the most potent antibacterial activity among three different extracts of gendola leaves, namely n-hexane extract, ethyl acetate extract, and 70% ethanol extract against Staphylococcus aureus and Escherichia coli. The research followed a laboratory-based experimental approach that involved maceration extraction using three different solvents and antibacterial activity testing through the well-diffusion method. Each extract was assessed at five different concentrations (20%, 40%, 60%, 80%, and 100% w/v) and compared to positive control chloramphenicol (0.3% v/v) and negative control DMSO (10% v/v). The results showed that only the n-hexane extract exhibited no antibacterial activity. In contrast, the ethyl acetate and 70% ethanol extracts exhibited more effective antibacterial activity against Staphylococcus aureus than Escherichia coli, with ethyl acetate extract displaying the most potential antibacterial activity.
Co-Authors Diah Muldianah Marsah Rahmawati Utami