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All Journal Jurnal Biologi Tropis
Muhammad Ghifari Rifanhsa
Universitas Mataram
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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The Role of Neutrophil in The Pathophysiology of Frailty Syndrome Muhammad Ghifari Rifanhsa; Ilsa Hunaifi; Ika Primayanti
Jurnal Biologi Tropis Vol. 23 No. 4 (2023): October - December
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i4.5780

Abstract

Neutrophils, also known as polymorphonuclear leukocytes, play a significant role in fueling systemic inflammation and tissue damage within the context of frailty, a clinical syndrome associated with increased susceptibility to stressors and decreased functional performance typically linked to aging. This literature review delves into the interplay between neutrophils and frailty, shedding light on their contribution to age-related systemic inflammation. The investigation explored the correlation between heightened neutrophil levels, diminished physical activity, increased frailty, and elevated white blood cell counts. These findings underscore the substantial role of neutrophils in the development of frailty, necessitating further research to enhance comprehension of their involvement for more effective prevention and intervention strategies. The implications of this study emphasize the importance of tailored exercise regimens, promoting optimal nutrition practices, efficiently managing chronic inflammation, and improving the control of chronic diseases as essential approaches to address frailty among older individuals.
Co-Authors Ika Primayanti Ilsa Hunaifi