Rini Nindela
Department of Neurology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia

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Genetic Factors Affecting Neuroplasticity Ziske Maritska; Muhammad Fakhri Altyan; Ardy Oktaviandi; Muhammad Barkah; Amirah Dhia Nabila Sinum; Emelda Emelda; Hawari Martanusa; Rini Nindela; Nita Parisa; Bintang Arroyantri Prananjaya; Puji Rizki Suryani; Eka Febri Zulissetiana
Sriwijaya Journal of Medicine Vol. 6 No. 2 (2023): Vol 6, No. 2, 2023
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v6i2.152

Abstract

Neuroplasticity pertains to the brain's ability to adjust functions or structure in response to events and is an important factor for skill-learning development as well as functional recovery from a neurological disorder. Numerous factors could influence neuroplasticity processes. This literature review aims to discuss the roles of genetic factors in neuroplasticity. The literature search was conducted using the keywords “neuroplasticity”, genetics”, “genes”, and polymorphism” in search engines like google scholar and PubMed, covering original articles, reviews, and text book both in Bahasa Indonesia and English for the last ten years. Genetic variation including gene polymorphism was responsible for the impact of BDNF, ApoE, and dopamine on the functional neural repair of the brain. Certain processes might directly influence neuroplasticity; others might interfere indirectly through the process. A deeper insight into genetic influence regarding neuroplasticity could lead to a better understanding and potential improvement of treatment.
Knowledge, Attitudes, and Preventive Behaviors Towards Stroke: A Study Among Employees of PT. PP London Sumatra Indonesia Tbk. Palembang Branch Fatimah Khairunnisa Lubis; Pinto Desti Ramadhoni; Rini Nindela
Sriwijaya Journal of Medicine Vol. 5 No. 3 (2022): Vol 5, No. 3, 2022
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v5i3.166

Abstract

A stroke occurs when a blood vessel that carries oxygen and nutrients to the brain is either blocked or ruptured. If the blood supply to part of the brain is interrupted or stopped, this can cause brain cells to die. Stroke is a health problem that must be noticed and understood by the whole community considering the high mortality and disability rates among working-age adults caused by this disease. Limited public knowledge towards stroke will result in no/lack of prevention efforts and can lead to delays in treating stroke. This research is a descriptive study with a cross-sectional approach that aims to describe the knowledge, attitudes, and preventive behaviors towards stroke among employees of PT. PP London Sumatra Indonesia Tbk. Palembang Branch. The primary source for the data used was an online questionnaire addressed to 48 employees of PT. PP London Sumatra Indonesia Tbk. Palembang Branch as the study subjects. Based on the results of measuring the variables, it can be concluded that most of the employees of PT. PP London Sumatra Indonesia Tbk. Palembang Branch have poor knowledge, good attitudes, and poor preventive behaviors towards stroke.