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This Author published in this journals
All Journal Biomedical Journal of Indonesia The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Florinda Ilona
Department of Anatomical Pathology, Faculty of Medicine, Universitas Trisakti, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

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Mucinous Tumors of the Ovary: Current Diagnosis in Histopathological Perspective Florinda Ilona; Dyah Ayu Woro; Reza Aditya Digambiro
Biomedical Journal of Indonesia Vol. 9 No. 3 (2023): Vol 9, No 3, 2023
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v9i3.163

Abstract

Epithelial malignant tumors account for around 90% of all ovarian malignancies and are the most deadly gynecological malignancies and mucinous borderline ovarian tumors are the most common cases in Asia. According to World Health Organization (WHO) 2020, mucinous ovarian tumors are divided into mucinous cystadenoma, borderline mucinous tumor and mucinous carcinoma. Histopathological features of benign, borderline and invasive mucinous carcinoma can be found together in one tumor. The coexixtence of these varied morphological features makes it difficult to establish a diagnosis due to the limited section evaluated and the large size of tumor. It can contribute to inaccurate diagnosis due to heterogeneity of the morphological features. Metastatic mucinous tumors which often resemble primary mucinous tumors in the ovaries.
Colonic Leiomyoma Presenting as Sigmoid Volvulus in a Young Male Reza Aditya Digambiro; Gerie Amarendra; Florinda Ilona; Julian Chendrasari; Samuel Abiodun Kehinde
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 27, No 1 (2026): VOLUME 27, NUMBER 1, April, 2026
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/271202695-100

Abstract

Colonic leiomyomas are rare tumors that originate from the smooth muscle layer of the colon and are infrequently observed in young individuals. This case report represents a 21-year-old male who presented with a 2-month history of progressive abdominal distension, persistent vomiting, early satiety, and bloating. Computed tomography (CT) of the abdomen suggested sigmoid volvulus with associated bowel obstruction. However, exploratory laparotomy revealed a well-defined, firm intramural mass in the sigmoid colon, leading to segmental resection and primary anastomosis. Histopathological analysis showed intersecting fascicles of bland spindle cells with eosinophilic cytoplasm and cigar-shaped nuclei without atypia or mitotic activity. Immunohistochemistry confirmed positivity for smooth muscle actin (SMA) and negativity for CD117, supporting a diagnosis of colonic leiomyoma and excluding gastrointestinal stromal tumor (GIST). The patient’s postoperative course was uneventful, with complete resolution of obstructive symptoms and restoration of normal bowel function. This case highlights the diagnostic challenge of differentiating colonic leiomyoma from other causes of bowel obstruction, particularly when presenting with features mimicking sigmoid volvulus. It also emphasizes the critical role of histopathology and immunohistochemistry in establishing a definitive diagnosis. Clinicians should consider rare benign tumors in the differential diagnosis of young patients with signs of bowel obstruction.
Co-Authors Dyah Ayu Woro Gerie Amarendra Julian Chendrasari Reza Aditya Digambiro Samuel Abiodun Kehinde