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All Journal Jurnal Mandala Pharmacon Indonesia Bubungan Tinggi: Jurnal Pengabdian Masyarakat Emasains : Jurnal Edukasi Matematika dan Sains Journal of Pharmaceutical and Sciences. Jurnal Pharmactive
Ella Yunita
Prodi D3 Farmasi, Fakultas Kesehatan, Institut Teknologi Dan Kesehatan Bintang Persada
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Education Environmental Science Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Aktivitas Antioksidan dan Toksisitas Fraksi Etil Asetat dan Fraksi N-Heksan Daun Pegagan (Centella Asiatica L.) Ella Yunita; Dyah Ratna Ayu Puspita Sari
Jurnal Mandala Pharmacon Indonesia Vol. 8 No. 1 (2022): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v8i1.167

Abstract

Antioksidan berperan penting untuk melindungi sel terhadap pengaruh radikal bebas. Tumbuhan yang berperan sebagai antioksidan alami adalah pegagan (Centella asiatica) dan banyak digunakan dalam pengobatan tradisional. Tujuan penelitian ini adalah mengetahui aktivitas antioksidan (IC50) dari fraksi etil asetat dan n-heksan daun pegagan dan toksisitasnya (LC50) terhadap Artemia salina Leach. Pengujian antioksidan dilakukan dengan metode DPPH (1,1-diphenyl-2-picrylhydrazyl) menggunakan spektrofotometer UV-Vis dan uji toksisitas dengan metode BSLT (Brine Shrimp Lethality Test). Hasil penelitian menunjukkan nilai IC50 fraksi etil asetat sebesar 325 mg/L (kategori lemah) dan fraksi n-heksan 731 mg/L (kategori tidak aktif) sedangkan nilai LC50 pada fraksi etil asetat yaitu 1202 mg/L (kategori tidak toksik) dan fraksi n-heksan yaitu 2818 mg/L (kategori tidak toksik).
Potensi Antibakteri Pegagan (Centella asiatica) Terhadap Bakteri Gram Positif dan Gram Negatif Ella Yunita; Puspita Sari Dyah Ratna Ayu
Emasains : Jurnal Edukasi Matematika dan Sains Vol. 9 No. 2 (2020): September 2020
Publisher : FPMIPA IKIP PGRI Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (156.744 KB) | DOI: 10.5281/zenodo.4305192

Abstract

Infeksi merupakan salah satu faktor penyebab utama morbiditas dan mortalitas diseluruh dunia.Terapi utama infeksi yaitu dengan penggunaan antibiotik. Namun penggunaan antibiotik sintetis dikaitkan dengan efek samping dan perbaikan progresif resistensi antimikroba. Oleh karena itu, diperlukan alternatif dalam terapi infeksi yaitu dengan memanfaatkan sumber daya alam yang ada. Centella asiatica yang dikenal dengan nama pegagan di Indonesia. Pegagan biasa digunakan dalam pengobatan tradisional dan telah terbukti memiliki berbagai aktivitas farmakologi, salah satunya sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui potensi antibakteri pegagan terhadap berbagai bakteri, baik gram negatif maupun positif. Hasil dari review ini menyatakan bahwa ekstrak pegagan memiliki potensi dalam menghambat pertumbuhan bakteri gram positif maupun negatif.
Improving Digital Health Information Literacy for Adolescents through Search Engine Optimization Gusti Ayu Oviani; I Gede Bagus Indra Marangyana; Ni Luh Gde Mona Monika; Ella Yunita
Bubungan Tinggi: Jurnal Pengabdian Masyarakat Vol 6, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/btjpm.v6i2.11637

Abstract

Internet use is increasing every year, most of the reason is finding information (80.1%). Along with this, misinformation is circulating, including health information, so digital literacy is needed, especially for teenagers or Generation Z who are technology savvy. This activity aims to increase teenagers' digital literacy and help them search for appropriate health information through search engines. This Community Service is carried out using the Participatory Action Research (PAR) method with direct face-to-face presentation of material and practice on the given topic. Participants were 43 high school/equivalent level students aged 15-19 years. Most participants were 16 years old (46.51%) and female (88.37%). The average knowledge of participants regarding appropriate health information in the pre-test was 60.21, and the post-test was 88.65. A total of 40 out of 43 participants experienced an increase in scores (93.02%) after lectures and practice. This activity concluded that participants' knowledge and skills increased regarding using search engines to manage appropriate health information.
PROFIL PENGGUNAAN OBAT PADA PASIEN DEPRESI RAWAT JALAN DI APOTEK “X” DENPASAR PERIODE JANUARI-APRIL 2022 Putu Ika Indah Indraswari; Ni Luh Sudi Astini; Ella Yunita
Journal Pharmactive Vol. 1 No. 2 (2022): Jurnal Pharmactive Oktober
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

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Abstract

Depression is a mood disorder characterized by deep feelings of sadness and indifference The symptoms of depression in adolescents are often characterized by feelings of irritability, distress, fear, lacklusterness, sadness, conflicts with friends, and conflicts with family. The highest incidence of depression was in the Southeast Asian region of 86.94 (27%) out of 322 billion individuals. Indonesia itself is in fifth place with a depression incidence rate of (3.7%). This study aims to determine the profile of drug use in outpatient depression patients at Karuna Pharmacy for the period January-April 2022. This research is a descriptive research that uses a cross-sectional research design with a retrospective approach and is processed qualitatively. The results of a study of 110 patients who entered the inclusion criteria, namely the use of antidepressants, namely selective serotonin reuptake inhibitors (SSRI) class drugs with a combination of psychotropic group drugs with a total of 53 (48.18%) people
GAMBARAN FAKTOR-FAKTOR YANG MEMPENGARUHI MINAT MASYARAKAT TERHADAP VAKSIN COVID-19 DI DESA MANGGISSARI KECAMATAN PEKUTATAN Marangyana I Gede Bagus Indra; Yunita Ella; Yunita Sari Ni Kadek Dwi
Journal Pharmactive Vol. 2 No. 1 (2023): Jurnal Pharmactive April
Publisher : Institut Teknologi dan Kesehatan Bintang Persada

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Abstract

This study aims to describe the factors that influence people's interest in the Covid-19 vaccine in Manggissari Village, Pekutatan District. This type of research is a quantitative study using the Cross-Sectional method. The sampling technique in this study was Simple Random Sampling, the total sample population was 237 in Manggissari Village, Pekutatan District. The results obtained from the frequency distribution show that from a total sample of 237 it can be seen that as many as 23.2% of the respondents who have not been vaccinated, not yet fully vaccinated (27.4%) and have had complete vaccines (49.4%), the community still has mostly low knowledge (49.8%), lack of information about the covid-19 vaccine (15.6%), lack of support from family (49.4%) and the influence of the community environment mostly (46.4%) . Based on the research above, there are factors that influence public interest in the Covid-19 vaccine. This research is expected to increase high awareness of carrying out the Covid-19 vaccination.
Formulasi Transdermal Patch Nanoemulgel Ekstrak Dadap Serep (Erythrina subumbrans (Hassk.) Merr.) dan Rimpang Kencur (Kaempferia galanga L.) sebagai Kandidat Laktagogum Herbal Berbasis Usadha Ni Luh Gde Mona Monika; Ella Yunita
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 2 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i2.1510

Abstract

Traditional Usadha-based herbal lactagogues, such as Erythrina subumbrans and Kaempferia galanga, are used by lactating mothers; however, their delivery in practical, standardized forms is limited. This study aimed to formulate a nanoemulgel transdermal patch containing E. subumbrans extract and K. galanga extract, evaluate its physicochemical properties, and assess its safety for skin irritation as a potential herbal lactagogue. Extracts of E. subumbrans and K. galanga were added to the nanoemulsion base. The nanoemulsions were incorporated into HPMC/PVP-based transdermal patch matrices by solvent casting. The resulting patches were evaluated for physicochemical properties and tested for skin irritation. Phytochemical screening confirmed the presence of flavonoids, tannins, triterpenoids, saponins, and alkaloids in both extracts. The total flavonoid contents were 47.44 mg QE/g for E. subumbrans and 36.79 mg QE/g for K. galanga. The nanoemulsion exhibited greater than 90% transmittance, mean droplet size of 7.79 nm, and polydispersity index (PDI) of 0.193. The patches met acceptable physical criteria, including a thickness of 0.20 mm, weight variation with %CV less than 10%, and folding endurance over 300. pH values ranged from 6.00 to 6.58. In a human patch test, no erythema or edema was observed; only mild pruritus (mean = 0.2) was reported in two participants. The formulated nanoemulgel transdermal patches demonstrated favorable physicochemical properties and were non-irritating. These patches show potential as a herbal lactagogue delivery system; further studies on lactation  efficacy and long-term stability are recommended.
Co-Authors Dyah Ratna Ayu Puspita Sari I Gede Bagus Indra Marangyana Indraswari, Putu Ika Indah Ni Luh Gde Mona Monika Ni Luh Gde Mona Monika Ni Luh Sudi Astini Oviani, Gusti Ayu Yunita Sari Ni Kadek Dwi