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Hesti Setiastuti
Departemen Pulmologi, Rumah Sakit Umum Daerah Kota Tangerang

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MANIFESTASI NEUROLOGI PADA PASIEN COVID-19 DI RUMAH SAKIT UMUM DAERAH KOTA TANGERANG SEBAGAI PUSAT RUJUKAN COVID-19 PROVINSI BANTEN Hananto Pratignyo; Paulina Thiomas; Hesti Setiastuti; Usynara Usynara; Fitrie Rahayu; Virginia Nuriah
NEURONA Vol 38 No 2 (2021)
Publisher : PERDOSNI

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Abstract

Introduction: Coronavirus Disease 2019 (COVID-19), caused by SARS-CoV-2, first reported in Wuhan by December 2019, spreading rapidly to various countries. World Health Organization (WHO) has designated COVID-19 as a global pandemic. Although the main clinical manifestation is the respiratory system, neurological symptoms have been reported. There are little data on neurological manifestations in COVID-19 patients, especially in Indonesia. Aim: To determine the neurological manifestations in COVID-19 patients. Methods: This is a retrospective observational study. Data were collected from medical records of hospitalized COVID-19 patients at Tangerang City General Hospital in the period April-August 2020. Data collection based on age, sex, comorbidity, general symptoms, neurological symptoms, laboratory and radiological findings. Neurological examinations were done by two neurologists. Results: Of 492 COVID-19 patients, there were 25 (5%) who had neurological manifestations, the proportion was male (52%) and aged over 60 years (44%). Of the 25 patients, 13 (52%) were confirmed COVID-19. Twenty patients (80%) have comorbidities such as hypertension, diabetes mellitus, vascular disease, tuberculosis, and chronic kidney disease. The neurological manifestations that were found were cerebrovascular disease (50%), meningoencephalitis (7.7%), vertigo (23%), anosmia (15.4%), and myalgia (3.8%). Seven patients (28%) died and 18 patients (72%) had clinical improvement. Discussion: COVID-19 can be accompanied by a variety of neurological symptoms. The neurological manifestations can be found in the central nervous system, peripheral nerves, and musculoskeletal. During a pandemic, COVID-19 is considered a differential diagnosis in patients with neurological symptoms to increase awareness and prevent further transmission. Keywords: Cerebrovascular, COVID-19, manifestation, neurology