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All Journal Jurnal MedScientiae
William Wibowo
Departemen Farmakologi, Fakultas Kedokteran Dan Ilmu Kesehatan, Universitas Kristen Krida Wacana, Jakarta, Indonesia.
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Studi Literatur Pengaruh Pemberian Zinc Terhadap Status Gizi Pada Anak-Anak Melita Tanjung; William Wibowo; Gracia Winaktu; Marina Rumawas
Jurnal MedScientiae Vol. 2 No. 3 (2023): Desember
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i3.2986

Abstract

During childhood, rapid growth occurs so that adequate intake is needed to grow optimally, but low appetite is one of the problems often faced. Based on data from WHO (2017), Indonesia is the third country with the highest prevalence of stunted toddlers in Southeast Asia with an average of 36.4% in 2005-2017. One of the causes of lack of appetite and nutrition is zinc deficiency. Therefore, this study review aims to analyze the effect of zinc administration on nutritional status in children. Literature searches were conducted on several databases, namely Pubmed, Google Scholar, and the National Library of Indonesia website. The keywords used were "zinc", "appetite", "children" and 10 journals from 2011 to 2020 were obtained for review. The inclusion criteria were journals from the last 10 years, zinc affecting appetite, and children aged 6 months - 12 years. Administration of 10 mg zinc per day for at least 12 - 24 weeks and a child's serum zinc level of <75 μg/dL had a significant appetite enhancing effect. Zinc supplementation can increase the total intake of calories, carbohydrates, protein, and fat leading to an increase in weight, height, body mass index, and nutritional status of children.
Penggunaan Tanaman Herbal Bawang Putih (Allium Sativum L) Terhadap Aterosklerosis Penyebab Penyakit Jantung Koroner Gracea S Manufandu; William William; William Wibowo
Jurnal MedScientiae Vol. 2 No. 3 (2023): Desember
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i3.3016

Abstract

Background: DKI Jakarta has the highest CAD disease rate at 1.9% based on the 2018 Riskesdas. Deaths from CAD are predicted to increase to 23.3 by 2030. Atherosclerosis is an inflammation that occurs due to the deposition of fat called atheroma. Currently, many studies are conducted to reduce cholesterol levels in the blood using natural ingredients such as garlic which is considered to have many advantages. The purpose of this study is to determine the important compounds in garlic that can reduce cholesterol levels, and become anti-atherosclerosis in blood vessels. Methods: Literature review based on articles and journals adjusted by PICO (Population, Intervention, Control, Outcome) and PRISMA Flow Diagram Generator method. Journals were searched in medical databases through Google Scholar, PubMed, and ProQuestd. Results: Based on the literature, garlic compounds that can reduce LDL levels and increase HDL have been studied, namely non-volatile γ-glutamyl-Salk(en)yl-L-cysteine or alliin . Conclusion: The presence of active compounds contained in garlic can significantly reduce the risk of atherosclerosis in coronary heart disease because it can reduce cholesterol levels in the blood and plaque in atherosclerosis.
Co-Authors Gracea S Manufandu Gracia Winaktu Marina Rumawas Melita Tanjung William William