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The Association of Physical Activity and Sleep Quality with Baroreceptor-Mediated Blood Pressure Regulation in Healthy Adult Women Tatius, Bintang; Nabil Hajar; Herianto Sibuea
Jurnal EduHealth Vol. 16 No. 03 (2025): Jurnal EduHealt, Edition July - September , 2025
Publisher : Sean Institute

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Abstract

Baroreceptor-mediated blood pressure regulation is a vital autonomic mechanism influenced by various physiological factors, including physical activity and sleep quality. However, few studies have explored these relationships specifically in healthy adult women. This study aimed to examine the association between physical activity levels and sleep quality with baroreceptor function, measured through blood pressure changes from supine to standing positions. A cross-sectional analytical study was conducted involving 55 healthy adult women selected by purposive sampling from participants of community exercise programs at Klinik Pratama Unimus and Yayasan Al-Muqorrobin, Semarang. Participants completed the International Physical Activity Questionnaire (IPAQ) and Pittsburgh Sleep Quality Index (PSQI), followed by measurement of systolic, diastolic, and pulse pressure differences during the Schellong test. Baroreceptor response was operationalized as the difference in blood pressure and pulse rate from supine to erect positions. Data were analyzed using Spearman's rank correlation in SPSS version 25. A significant correlation was observed between physical activity levels and systolic blood pressure changes (r = 0.272, p = 0.045), as well as between sleep quality and diastolic blood pressure changes (r = -0.336, p = 0.012), indicating that higher physical activity and better sleep quality are associated with more stable baroreceptor responses. In conclusion, physical activity and sleep quality are significantly associated with baroreceptor-mediated blood pressure regulation in healthy adult women. Our findings suggest that lifestyle factors may play a role in maintaining autonomic cardiovascular function.
Civamide Nasal Spray: A Breath of Fresh Air in Migraine and Cluster Headache Therapy? Insights from A Systematic Review Cyntia Arum; Danar Dwi Anandhika; Nabil Hajar; Moh. Iqbal Setiawan; Fatima Khiarun Nisa; Suwandhi; Firza Yoga Baskoro; Hera Dwi Priharti
Magna Neurologica Vol. 4 No. 1 (2026): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v4i1.2208

Abstract

Background: Migraines and cluster headaches are severe neurological disorders characterized by complex pathophysiological mechanisms, particularly involving the trigeminal nerve and vascular inflammatory responses. Both conditions primarily affect the trigeminal nerve, a key pathway in pain transmission, and are closely associated with vascular inflammation. Migraines are typically characterized by recurrent, unilateral, and intense headaches, whereas cluster headaches are marked by excruciating pain, often localized around the eye. These disorders are multifactorial, with various mechanisms contributing to their initiation and persistence. Civamide nasal spray, which modulates neural pathways, has emerged as a promising therapeutic option for targeted pain relief. This study aims to evaluate the effectiveness of Civamide nasal spray in managing these debilitating headaches. Objective: To assess the efficacy of civamide nasal spray in treating migraine and cluster headache attacks. Methods: This study followed the Synthesis without Meta-analysis (SWiM) guideline. A systematic search was conducted using a predefined query in Medline, Google Scholar, and Cochrane Central Library. Eight independent reviewers screened studies for eligibility based inclusion criteria and assessed the risk of bias using the Cochrane RoB 2.0 tool. Results: Two eligible studies were analyzed. Participants receiving civamide demonstrated a greater reduction in weekly headache frequency compared with those receiving a placebo. Additionally, civamide treatment was associated with decrease in pain intensity. Conclusion: The findings suggest that civamide nasal spray effectively reduces both the frequency and severity of headaches. Nonetheless, further investigations, particularly evaluating its long-term preventive use, are required to establish its clinical role in migraine and cluster headache management.
Hubungan Durasi Kerja, Masa Kerja, dan Penggunaan Alat Pelindung Diri terhadap Faal Paru pada Pekerja Penyortir Bawang Merah Nila Nurdiana N; Susilo Budi Pratama; Nabil Hajar; Muslimah, Muslimah
USADA NUSANTARA : Jurnal Kesehatan Tradisional Vol. 3 No. 2 (2025): Juli: USADA NUSANTARA
Publisher : Institut Nalanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47861/usd.v3i2.2406

Abstract

Data from the International Labor Organization (ILO) in 2018 states that 270 million workers experience work-related accidents every year. Agricultural industry workers are vulnerable to exposure to dust in the work environment, which can cause lung function problems. If dust is present in excessive amounts for a long period of time, it can cause pathological damage to humans making them susceptible to disease, especially pneumoconiosis. The aim of this study was to analyze the relationship between work duration, length of service, and use of personal protective equipment on lung function in shallot sorting workers. This research method is quantitative observational analytic using a cross sectional design. This study used a questionnaire and spirometry examination. The sample for this research was red onion sorting workers in Tawangharjo Village who were taken using total sampling. Data analysis used the chi square correlation test. The total sample that met the inclusion criteria was 45 respondents. The results of the chi square correlation test showed p<0.05, which means there is a significant relationship between work duration, work period, and use of personal protective equipment on lung function. There is a significant relationship between work duration, length of service, and use of personal protective equipment on lung function in shallot sorting workers.