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All Journal Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya
Findra Setianingrum
(SCOPUS ID: 57203061705) Department of Parasitology, Faculty of Medicine, University of Indonesia
Health Professions Medicine & Pharmacology

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The body mass index profiles in chronic pulmonary aspergillosis: trend and variability in post tuberculosis patients Findra Setianingrum; Anna Rozaliyani
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 01 (2024): Qanun Medika Vol 08 No 01 January 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i01.20763

Abstract

Tuberculosis (TB) is the main risk factor for chronic pulmonary aspergillosis, especially in patients with residual cavitary lesions after completion of TB therapy. The body mass index (BMI) is one of the established markers in predicting the mortality of CPA. However, the data regarding BMI profiles of CPA patients in Indonesia is still limited. We evaluated the BMI profiles of CPA patients among post-TB patients. Patients diagnosed as CPA based on clinical, radiology and the Aspergillus IgG test. 50 patients were included with a mean age of 35 years; 13 patients met the criteria of CPA. The overall median of BMI in these patients was 21. The median BMI in the CPA group was 19,3. The lowest (19,8) median BMI value was observed in the positive Aspergillus IgG group (11,5 – 30 mg/L) with a minimum BMI of 14,7 and a maximum BMI of 29,2. The differences in median BMI across CPA and non CPA groups and Aspergillus IgG level were not statistically significant. However, there is a trend that lower BMI were distributed among patients with positive Aspergillus IgG. More than one third of CPA patients in this study were classified as underweight. Future study is necessary to better depict the BMI profiles in larger scale of populations of CPA in Indonesia in order to achieve better diagnosis and management of CPA.
KAVITAS PARU DENGAN PENYEBAB INFEKSI Findra Setianingrum; Finny Nandipinto; Anna Rozaliyani
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 10 No 01 (2026): Qanun Medika Vol 10 No 01 January 2026
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v10i01.30047

Abstract

Pulmonary cavities are an important radiological finding in various infectious and non‑infectious diseases.​ Infection‑related cavities are usually associated with tuberculosis (TB), non‑tuberculous mycobacterial (NTM) infection, chronic pulmonary aspergillosis, and echinococcosis, each with distinct mechanisms of formation and radiologic patterns.​ In TB and NTM, tissue necrosis and bronchiectasis lead to the formation of cavitary spaces that serve as reservoirs for organisms with a high burden and facilitate transmission.​ Residual cavities may then undergo secondary colonization by Aspergillus spp, resulting in a spectrum of chronic pulmonary aspergillosis with findings such as aspergilloma and thick‑walled cavities.​ Echinococcus forms cysts that, when ruptured, can appear as cavitary lesions with the “water lily” sign, adding yet another differential diagnosis for pulmonary cavities.​ Understanding radiologic patterns, pathogenesis, and microbiological correlations can be used as an important clue to distinguish etiologies and to select appropriate management for patients.
Co-Authors Anna Rozaliyani Anna Rozaliyani Finny Nandipinto