Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal Berkala Kedokteran
M, Satriyandi
Fakultas Kedokteran Universitas Lambung Mangkurat
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Influence of Extract Swiftlet Nest (Collocalia Fuciphago) as Antihyperglycemia to Circulating Endothelial Cells in Rat (Rattus novergicus) Induced by Streptozotocin Alexandra, Francisca Diana; M, Satriyandi; Frethernety, Agnes; Triawanti, Triawanti
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v14i1.4528

Abstract

Abstract: Hyperglycemia could increase the oxidative stress by catalyzes the formation of free radical as anion superoxide(O2-). Oxidative stress will effect in endothelial damaged. This study aimed to evaluated the influence of  extract swiftlet nest  (Collocalia fuciphago) to glucose level and  CEC in rat (Rattus novergicus). Rats were classified into 4 groups, there were control group (K) and 3 treatments group (dose 1; 10 and 100 mg / kgBW) The seventh day  after induced by Streptozotozin (i.p),  the rats  had increased  glucose ± 102 – 108 mg/dL, then treated  with the  extract of   Swiftlet  nest for 28  days  by  oral.  The CEC was measured by Hladovec method. The results showed  the blood glucose level were significant differences ( p = 0.035). The number of CEC decrease significantly (p=0,002). In  conclusion  that extract of Swiftlet  nest  can effect  to decrease  glucose level and CEC number in plasma rat (Rattus novergicus) Keywords: Hyperglycemia, Circulating Endothelial Cells, Collocalia fuciphago
Potency of Swallow Nest Extract (Collocalia fuciphago) as Pancreaprotector Through Oxidative Mechanism in Rats (Rattus norvegicus) Induced by Streptozotocin Frethernety, Agnes; M, Satriyandi; Alexandra, Francisca Diana
Berkala Kedokteran Vol 14, No 1 (2018)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v14i1.4534

Abstract

Abstract: Diabetes mellitus is a clinical syndrome with characteristics of hyperglycemia. Hyperglycemia can lead to the formation of excessive free radical compounds that trigger oxidative stress, especially on pancreatic β cells. Swallow nest contains amino acids which are insulin-forming compounds and glutathione that can act as a major reducing agent and antioxidant defense. The purpose of this study is to analyze the effect of swallow’s nest water extract as a pancreaprotector through oxidative mechanism in rats (Rattus norvegicus) induced by streptozotocin. The rats induced by streptozotocin at a dose of 40 mg/kg BW and then randomly divided into 4 groups. Control groups were given aquades and 3 treatment groups, respectively were administered swallow’s nest water extract at doses of 1, 10, 100 mg/kg BW for 21 days. Fasting blood glucose levels were measured on 7, 14 and 21 day. MDA measured after  the animal is determined  at day 28th.Level of  fasting blood glucose and MDA were analyzed by statistic using Kruskal Wallis test followed by multiple comparisons Mann Whitney test. There was a significant decrease in fasting blood glucose level with p = 0.04 in all treatment groups compared the control group. The administration of swallow nest extract significantly decreased MDA pancreas with p value = 0.000 and dose 100 mg/kgBW extract of swallow’s nest significantly decrease pancreatic MDA level. The administration of swallow’s nest water extract shows decrease of fasting blood sugar and has a protective effect on the rats’ pancreas  through oxidative mechanism. Keywords: Swallows nest extract, MDA
Co-Authors Alexandra, Francisca Diana Frethernety, Agnes Triawanti Triawanti