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All Journal Medicinus : Jurnal Kedokteran Ophthalmologica Indonesiana
Saraswati Anindita Rizki
Unknown Affiliation
Health Professions Medicine & Pharmacology Public Health

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Outcomes of Treating a late case of Herpes Zoster Ophthalmicus masquerading as Orbital Cellulitis: A Case Report: Poster Presentation - Case Report - Ophthalmologist JOSIAH IRMA; Saraswati Anindita Rizki; Jennifer Angelina; Jovita; Jennifer Handiokho
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/sa8pth15

Abstract

Abstract Introduction : Herpes zoster ophthalmicus (HZO) refers to a reactivated varicella-zoster virus involving the V1 nerve division. Although rare, previous reports have mentioned HZO cases masquerading as orbital cellulitis (HZO-OC). This report depicts the use of acyclovir, corticosteroids and citicoline in our HZO-OC patient with treatment delay. Case Illustration : A healthy 66 year old man presented to our clinic 4 weeks after signs of orbital cellulitis followed by vesicular rash following the CN V(1) dermatome were felt which was untreated. The right palpebra was edematous and erythematous. Hazy cornea, mixed injection, grade IV reverse RAPD, diminished direct and consensual reflex and external ophthalmoplegia of the right eye were noted. The diagnosis of HZO-OC with multiple cranial neuropathies OD was established. Topical and symptomatic treatment were given resulting no improvement. Ptosis of the right palpebra became present. The patient was then given systemic acyclovir, methylprednisolone and citicoline. Ophthalmoplegia improved after 2 months and ptosis improved after 4 months. Discussion : The use of systemic acyclovir and corticosteroids in HZO-OC patients were given promptly in previous literature. Multiple cranial nerve in our patient was thought to occur due to treatment delay. As improvement was not noted after topical treatment, these systemic treatments along with citicoline were added. Citicoline was added due to its ability to promote neural regeneration. Conclusion : Systemic acyclovir, corticosteroids and citicoline may still be beneficial for HZO-OC patients with delayed treatment.
Relationship Between Electronic Device Usage with Asthenopia in Workers at Pelita Harapan University Lippo Karawaci Harlendo, Sachio; Josiah Irma; Saraswati Anindita Rizki; Ruth Syeela Widianty
Medicinus Vol. 15 No. 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v15i2.10828

Abstract

Background: Breast cancer is the most common malignancy among women and a leading cause of cancer-related mortality. Early detection is crucial to improve survival outcomes. Mammography is considered the gold standard for screening women over 40 years, while ultrasonography (USG) is frequently used in younger women with dense breasts. However, diagnostic accuracy varies, and comparative studies in Indonesia remain limited. To compare the diagnostic accuracy of mammography and ultrasonography in differentiating benign and malignant breast lesions using histopathology as the Gold standard.   Methods: This cross-sectional analytic study included 91 patients who underwent mammography, ultrasonography, and histopathological confirmation at MRCCC Siloam Semanggi Hospital. Diagnostic parameters including sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, and area under the curve (AUC) were calculated. Statistical analysis used McNemar’s test and ROC curve analysis based on Hanley & McNeil’s method, with p < 0.05 considered significant.   Result: Ultrasonography demonstrated higher sensitivity (98.4%) and NPV (92.3%) than mammography (96.7% and 88.9%), indicating better ability to rule out malignancy. Mammography showed higher specificity (53.3% vs. 40.0%) and PPV (80.8% vs. 76.9%), reflecting better performance in identifying benign lesions. Overall accuracy was slightly higher for mammography (82.4%) compared to USG (79.1%). The AUC for mammography was 0.750 (95% CI: 0.630–0.870), while USG had an AUC of 0.692 (95% CI: 0.565–0.819). Overlapping confidence intervals indicated no statistically significant difference in diagnostic accuracy between the two modalities (p > 0.05).   Conclusions: Mammography and ultrasonography both demonstrated high diagnostic performance with complementary strengths. Mammography provided higher specificity and PPV, while USG offered superior sensitivity and NPV. Given the small difference in accuracy and overlapping AUC confidence intervals, no significant difference was found between the two modalities. Combined use of mammography and USG may improve diagnostic accuracy in clinical practice.
Co-Authors Harlendo, Sachio Irma, Josiah Jennifer Angelina Jennifer Handiokho Jovita Ruth Syeela Widianty