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Outcomes of Treating a late case of Herpes Zoster Ophthalmicus masquerading as Orbital Cellulitis: A Case Report: Poster Presentation - Case Report - Ophthalmologist JOSIAH IRMA; Saraswati Anindita Rizki; Jennifer Angelina; Jovita; Jennifer Handiokho
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/sa8pth15

Abstract

Abstract Introduction : Herpes zoster ophthalmicus (HZO) refers to a reactivated varicella-zoster virus involving the V1 nerve division. Although rare, previous reports have mentioned HZO cases masquerading as orbital cellulitis (HZO-OC). This report depicts the use of acyclovir, corticosteroids and citicoline in our HZO-OC patient with treatment delay. Case Illustration : A healthy 66 year old man presented to our clinic 4 weeks after signs of orbital cellulitis followed by vesicular rash following the CN V(1) dermatome were felt which was untreated. The right palpebra was edematous and erythematous. Hazy cornea, mixed injection, grade IV reverse RAPD, diminished direct and consensual reflex and external ophthalmoplegia of the right eye were noted. The diagnosis of HZO-OC with multiple cranial neuropathies OD was established. Topical and symptomatic treatment were given resulting no improvement. Ptosis of the right palpebra became present. The patient was then given systemic acyclovir, methylprednisolone and citicoline. Ophthalmoplegia improved after 2 months and ptosis improved after 4 months. Discussion : The use of systemic acyclovir and corticosteroids in HZO-OC patients were given promptly in previous literature. Multiple cranial nerve in our patient was thought to occur due to treatment delay. As improvement was not noted after topical treatment, these systemic treatments along with citicoline were added. Citicoline was added due to its ability to promote neural regeneration. Conclusion : Systemic acyclovir, corticosteroids and citicoline may still be beneficial for HZO-OC patients with delayed treatment.
Perbandingan Metode IQR vs Isolation Forest dalam Deteksi Outlier pada Data Klaim Asuransi di PT Askrindo Cabang Semarang ramadhani, jovita wayan; jovita; susanto, susanto
Jurnal Transformatika Vol. 23 No. 2 (2026): January 2026
Publisher : Jurusan Teknologi Informasi Universitas Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26623/transformatika.v23i2.13726

Abstract

Penelitian ini bertujuan untuk membandingkan dua pendekatan yang umum digunakan dalam deteksi outlier, yaitu metode statistik Interquartile Range (IQR) dan metode machine learning Isolation Forest, studi kasus data klaim asuransi di PT Askrindo Cabang Semarang. Data yang dianalisis mencakup nilai klaim dan durasi penyelesaian. Metode IQR secara univariat menemukan 9 klaim yang terklasifikasi sebagai outlier, yang terdiri atas 5 outlier nilai klaim, 3 outlier durasi penyelesaian, serta 1 outlier ganda. Sedangkan Isolation Forest secara multivariat dengan contamination 0,05 mendeteksi 6 klaim anomali, termasuk durasi penyelesaian sangat lama dan pola kombinasi variabel yang tidak wajar. Hasilnya IQR efektif untuk deteksi cepat nilai ekstrem, sedangkan Isolation Forest lebih cocok dalam mengenali anomali kompleks antar variabel.  Oleh karena itu, penggunaan metode IQR maupun Isolation Forest dapat disesuaikan dengan tujuan analisis karakteristik data.