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ANALYSIS OF RELATIONSHIP GESTATIONAL DIABETES MELLITUS WITH NEWBORN BABY WEIGHT AND LENGTH Enda Silvia Putri; Marniati; Khairunnas; Sufyan Anwar; Itza Mulyani; Siti Maisyarah Fitri Siregar; Sukma Elida; Suci Eka Putri; Ernawati; Arfriani Maifizar
Multidiciplinary Output Research For Actual and International Issue (MORFAI) Vol. 3 No. 4 (2024): January (January-March)
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/morfai.v3i4.1362

Abstract

Gestational Diabetes Mellitus (GDM), was a condition in which pregnant women experience higher blood sugar levels than usual. This can affect the development of the fetus and the health of the newborn. The purpose of the reasearch was to analyze the gestational relationship of diabetes mellitus with the newborn's weight and height. The research method uses a quantitative method with cross sectional design, the sample represents a total population of 126 people, data analysis using a chi square test using the application of SPSS 21.0. The results of the study show that there was a relationship between GDM and weight with values (P Value =1,00 ≥ α :0,05 and RP = 1,00) and the length of the newborn with value (P value =0,695 ≥ alpha :0,05, RP = 2,00). An abnormal blood sugar level in the mother during pregnancy affects the nutrition received by the fetus so affecting the length of the baby. Important advice for mothers at the time of pregnancies to observe blood sugar levels at normal levels by paying attention to nutrition intake and stress management through regular consultation with the nearest health officials and health services on a regular basis during the pregnant, so that the baby is born healthy especially the length of the body.
EFFECT OF ETHANOL EXTRACT OF BHEE FRUIT (MELASTOMA SP) ON CHOLESTEROL LEVELS IN DIABETIC MICE Mhd. Hermanda Syahputra; Rinawati; Suci Eka Putri; Cukri Rahma
Multidiciplinary Output Research For Actual and International Issue (MORFAI) Vol. 3 No. 4 (2024): January (January-March)
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/morfai.v3i4.1392

Abstract

Diabetes mellitus is a chronic disease that causes death. Diabetes is associated with increased total cholesterol levels. Insulin resistance causes glucose levels to increase in the blood and inhibits the circulation of food juice. The body will break down fat as an energy source due to glucose that cannot reach the body's cells, this causes an increase in cholesterol levels in the blood. Several studies have shown a correlation between increased blood glucose levels and increased cholesterol levels. Control of blood glucose levels in diabetics should be done so as not to cause an increase in blood cholesterol. Herbs are chosen as an alternative for antidiabetics. Bhee fruit (Melastoma Sp) has the potential to an antidiabetic because of its phytochemical content. In West Aceh, there has not been much research on diabetes herbal medicine and the use of Bhee Fruit as an herbal medicine. The purpose of this study was to determine the effect of ethanol extract of Bhee fruit on total cholesterol levels of alloxan-induced diabetic mice. Method: Laboratory experimental research with Complete Randomized Design (RAL) using 21 mice divided into 7 treatments namely KN, KP, KO, KD, P1, P2, and P3. Measurement of cholesterol levels using easy touch tools and Cholesterol strips. The dose of ethanol extract of Bhee fruit used is 100, 200, and 400 mg/kg body weight and given for 14 days. Data analysis was performed using One-way ANOVA and followed by the Duncan Analysis test. Results: Giving ethanol extract of Bhee fruit at doses of 100, 200, and 400 mg / dL was able to reduce total cholesterol levels in diabetic mice. Conclusion: Giving Bhee fruit extract affects reducing total cholesterol levels, with a dose of 400 mg/kg body weight which is most effective in reducing total cholesterol levels in diabetic mice. Suggestion: it is necessary to do further tests using different types of solvents and different doses.