Okti Ratna Mafruhah
Universitas Islam Indonesia

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THE ROLE OF MEDICATION LITERACY IN THE TREATMENT OF HYPERTENSIVE PATIENTS: A REVIEW Okti Ratna Mafruhah; Vita Widyasari
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 1 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i1.1071

Abstract

Hypertension, or high blood pressure, has become a major contributor to cardiovascular disease globally. Its prevalence continues to increase, necessitating intensive healthcare efforts. Medication literacy, or the skill of understanding and applying medication information, is crucial for chronic patients, including those with hypertension. However, there has been limited research on this topic, highlighting the need for a literature review of the levels and roles of literacy in the therapy of hypertensive patients. This study used a narrative review approach to analyze the findings of articles on medication literacy in hypertensive patients. This study employs a narrative review approach to analyze findings from various journals. The data were derived from articles focusing on medication literacy in hypertensive patients, identified through literature searches on PubMed from 2013 to 2023. The selected articles were published in international journals, have a full text, can provide data on the role of medication literacy in hypertensive patients, and use quantitative, qualitative, or mixed-methods research designs.Two studies included in the review originated from China. Both articles reported low literacy levels among hypertensive patients. Factors, such as education and income, can also influence literacy. These findings underscore the importance of improving medication literacy in hypertension management, emphasizing the need for better education and more effective development strategies. Both articles also emphasized the significance of medication literacy in the context of hypertension management; that is, they highlighted the need for improved medication literacy and provided evidence of the positive impact of medication literacy on blood pressure control...
Analisis Efektivitas Biaya Penggunaan Pioglitazone Dibandingkan Glimepiride Pada Pasien Diabetes Melitus Tipe 2 di Rumah Sakit Wilayah Kota Mataram Kholida Zhahara; Diesty Anita Nugraheni; Okti Ratna Mafruhah
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 7, No 1 (2026): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v7i1.35915

Abstract

Diabetes mellitus (DM) is a chronic disease requires long-term therapy, which can result in high medical costs. This study aims to analyze the cost-effectiveness of oral antidiabetic therapy with pioglitazone compared with glimepiride in type 2 diabetes mellitus outpatients at RSI Siti Hajar Mataram and RSUD H. Moh. Roeslan Kota Mataram from the hospital perspective. This research is an observational method with a cross-sectional design. Data were collected with retrospective and concurrent from medical record and treatment cost data of patients from May-Auguts 2025. Data analysis using the average cost-effectiveness ratio (ACER). The subject of this study is type 2 diabetes mellitus outpatients who met the inclusion and exclusion criteria, with patients received pioglitazone monotherapy and combination is 119 patients, while 133 patients received monotherapy and combination of glimepiride. The result showed that pioglitazone monotherapy could achieve a higher therapeutic target (80,82%) and had lower ACER value Rp 7.867,80 than the glimepiride. While the combination therapy of glimepiride-metformin could achieve a higher therapeutic target (78,57%) and had lower ACER value Rp 5.404,50 than the combination of pioglitazone-metformin. The conclusion of this study pioglitazone monotherapy is perceived to be more cost-effective than glimepiride, while the combination of glimepiride-metformin is perceived to be more cost-effective than combination of pioglitazone-metformin.