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All Journal Journal of Medical Laboratory in Infectious and Degenerative Diseases
Robi Akollo
UKIM
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Public Health

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Preferences for breeding places for Aedes spp. mosquitoes on materials and location of containers in the working area of Lateri Health Center, Ambon City Robi Akollo
Journal of Medical Laboratory in Infectious and Degenerative Diseases Vol. 2 No. 1 (2024): Juni
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jmid.v2i1.16

Abstract

Background: The mosquitoes Aedes aegypti and Ae. albopictus is a vector of dengue fever in Indonesia. Container characteristics such as material, color, location, shape, volume and water origin influence female Aedes spp mosquitoes in choosing a place to lay their eggs. Mosquito Ae. aegypti prefers artificial containers as a breeding place, while the Ae. albopictus prefers natural containers. Mosquito Ae. aegypti prefers to be indoors while the Ae. albopictus outdoors. Purpose: knowing the preferences for breeding places for Ae mosquitoes. aegypti and Ae. albopictus on materials and location of containers in the Lateri Health Center Working Area, Ambon City. Methods: This research is a descriptive and analytical study with a cross sectional research design. Larvae collection was carried out in Lateri and Lata villages, Lateri Health Center Working Area. Habitat characterization of Ae. aegypti and Ae. albopictus is carried out visually including the location and material of the container. Identification of larvae using the Aedes genus identification key with a microscope. Results: The container materials found at the research location were artificial containers. The basic materials for the containers made in this research are cement, ceramic, plastic, glass, rubber and aluminum. Mosquito larvae Ae. aegypti are more commonly found inside homes while the mosquito larvae of Ae. albopictus is more commonly found outside the home. Conclusions: Mosquito Ae. aegypti and Ae. albopictus uses artificial containers as a breeding place. Mosquito larvae Ae. aegypti are more commonly found inside homes, while Ae. albopictus outdoors
The Role of microRNA in the Regulation of BST-2 (bone marrow stromal antigen-2) Gene Expresion Robi Akollo; Vernando Yanry Lameky Lameky; Sahrir Sillehu
Journal of Medical Laboratory in Infectious and Degenerative Diseases Vol. 4 No. 1 (2026): Juni
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jmid.v4i1.47

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Background: MicroRNA (miRNA) is a non-coding RNA molecule that plays an important role in the regulation of post-transcriptional gene expression and is involved in various biological processes, including immune responses and disease development. MicroRNAs are involved in the regulation of various genes, one of which is Bone Marrow Stromal Antigen 2 (BST-2). Purpose: This study aims to examine the role of microRNA in regulating BST-2 gene expression. Methods: This study used a scoping review approach to examine the role of microRNA in the regulation of BST-2 gene expression. Research articles were obtained from the PubMed, Scopus, and Google Scholar databases, with publication years ranging from 2015 to 2025, and were selected using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Results: The results of the review show that several microRNAs, namely miR-129-5p, miR-760, miR-155, and miR-451a, act as negative regulators of BST-2 gene expression. MicroRNAs can bind to BST-2 mRNA, inhibiting translation and thereby reducing the production of BST-2 protein. The role of microRNA in regulating BST-2 has been identified in clinical various conditions, particularly cancer. Conclusions: microRNAs play a role in the regulation of BST-2 gene expression and have the potential to be developed as therapeutic targets or biomarkers in diseases associated with BST-2 dysregulation.
Co-Authors Sahrir Sillehu Vernando Yanry Lameky Lameky