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Journal : Al-Kimia

Sintesis Metil Ester dari Minyak Biji Kemiri (Aleurites Molluccana) Menggunakan Metode Ultrasonokimia Rahmawati Aziz; Aisyah Aisyah; Asriani Ilyas
Al-Kimia Vol 4 No 1 (2016): June
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (278.252 KB) | DOI: 10.24252/al-kimia.v4i1.1453

Abstract

Using the fuel oil is the basic necessary in the world now. But, the raw material cannot be updated.  To ensure the availability of the fuel oil so, the newest of alternative energy is explored it. One of the ways is biodiesel which made from vegetable oil. In this research is resulted from the transesterification reaction between candlenut oil and methanol by utilizing ultrasonic equipment. This research has passed some phases, they are the determining of acid number in oil then continued by creating biodiesel from ultrasonic wave 47 kHz. Identification of FTIR and GCMS are two methods which used to analyze the component compound in biodiesel product. The conversion number that be gotten from FAME with reaction of variation time 30, 40 and 50 in succession 0,037%, 0,029% and 0,018%. The result analysis of FTIR shows some of functional groups which are special from biodiesel. While the result of GCMS analysis is known that there are 5 component compounds in biodiesel namely ester methyl palmitic acid, ester methyl olead, stearata ester methyl, linoleic ester methyl and elaidic ester methyl.
Bioaktivitas Ekstrak Metanol Daun Pegagan (Centella Asiatica L.) Terhadap Pertumbuhan Bakteri Mycobacterium Tuberculosis Yusran Yusran; Asriani Ilyas; Asri Saleh
Al-Kimia Vol 4 No 1 (2016): June
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (242.582 KB) | DOI: 10.24252/al-kimia.v4i1.1456

Abstract

Plants gotu kola (Centella Asiatica L .Urban) is a wild plant that efficacious as remedies traditional cure disease tuberculosis (TB).TB is disease contagious infection caused by bacteria mycobacterium tuberculosis. Research aims to understand the ability extract methanol leaves gotu kola red and leaves gotu kola green and determines the concentration optimal extract methanol leaves gotu kola red and leaves gotu kola green and to know the comparison between extract methanol leaves gotu kola red with an extract methanol leaves gotu kola green in inhibits the activity of mycobacterium tuberculosis.Extraction done with the methods maceration use methanol and continued with evaporation until obtained extract viscous .Testing antibacterial activity done in a microscopic observation drug susceptibility ( mods ) use plate petri dish 24 hole with the variation of concentration ie 20%,40%, 60%, 80% and 100%.The results of testing show that extracts methanol leaves gotu kola red and leaves gotu kola green positive capable of inhibiting the growth of bacteria mycobacterium tuberculosis with inhibition optimal in concentration 80 % and 100 % characterized by the absence of growth bacteria colonies which are (-) or 0 %.Extract methanol leaves gotu kola green capable of inhibiting the growth of bacteria mycobacterium tuberculosis better than extract methanol leaves gotu kola red seen in concentration 40% and 60%.
Senyawa Geranil-1”, 3”-Diokso-Para-Kresol dari Ekstrak Etil Asetat (Etoac) Kulit Akar Paliasa (Kleinhovia Hospita Linn.) Asriani Ilyas
Al-Kimia Vol 1 No 2 (2013): December
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (262.266 KB) | DOI: 10.24252/al-kimia.v1i2.1625

Abstract

Isolation and identification of secondary metabolites from EtOac extract of the root bark of Kleinhovia hospita Linn. plant had been performed. Separation techniques used consisted of extraction, fractionation, and purification. The compounds obtained were tested and elucidated based on UV, IR, and NMR spectroscopy data.  A compound obtained was geranil-1”,3”-dioxo-para-chresol.
Active Compounds Of Ethyl Acetate Extract Of Stylotella Sp. Sponges From Selayar Islands Against Mcf-7 Breast Cancer Cells Asriani Ilyas; Sahyuni Hamzah; Firnanelty Firnanelty; Titik Andriani
Al-Kimia Vol 8 No 2 (2020): DECEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v8i2.12840

Abstract

Stylotella sp. sponge is a type of marine invertebrate animals that are widely distributed in Indonesian marine areas. One of the spreading areas of the Stylotella sp. sponge is in the Selayar Islands, South Sulawesi, Indonesia. Sponges have potential as a drug because they contain secondary metabolites. The aim study was to identify the types of secondary metabolite compounds and determine the bioactivity of Stylotella sp. compounds against MCF-7 breast cancer cells. The extraction method was used in the process of obtaining isolates because it is easy and economical. Testing the level of purity of isolates was carried out with three eluent systems which showed a single stain result. FTIR characterization results showed that pure isolates contained alkaloids which were characterized by the appearance of O-H, C-N, and C-H groups. The activity of MCF-7 cells using the colorimetric method showed an IC50 value of 14987.50 µg / mL, not toxic.