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All Journal IJOEP : International Journal of Ecophysiology Herbal Medicine Journal Jurnal Pengabdian Masyarakat Mandira Cendikia (JPKM-MC)
Andre Prayoga
Universitas Sari Mutiara Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Immunology & microbiology Social Sciences Other

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PEMANFAATAN EKSTRAK BUAH SALAK (Salacca zalacca (Gaertn.) Voss) SEBAGAI ANTI-AGING ALAMI DALAM SEDIAAN BODY SCRUB Riza Permata Dara; Siti Maimunah; Andre Prayoga
Herbal Medicine Journal Vol 7 No 1 (2024): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v7i1.97

Abstract

This study was aimed at formulating Salak fruit extract in a cream formulation and testing its anti-aging effectiveness. Flavonoid compounds in salak fruit are efficacious as antioxidants that are able to neutralize free radicals so they can improve signs of aging on the skin such as dry skin and enlarged pores and wrinkles. This research was conducted at the Pharmaceutical Chemistry Laboratory of Sari Mutiara Indonesia University in June-August 2023. The tools used were skin analyzer and moisture checker. Salak fruit samples were obtained from the Sihopur village Tapanuli Selatan regency, North Sumatra. The irritation test of three volunteers used salak extract cream with the highest concentration of 7%. The anti-aging activity test used 15 volunteers. Parameters measured include moisture content, number of pores and wrinkles. Statistical data was analyzed using the SPSS method. The results show that the ethanol extract of Salak fruit leaves can be formulated in a homogeneous type A / M cream dosage form, with a pH of 6,3-5,2, a viscosity of 19.000-47.000 cps, non-irritating and stable in storage for 12 weeks. The results of the analysis with the skin analyzer showed that the skin condition changed for the better, namely increased water content 32,3%, reduced pores 10,4% and wrinkles 13,2%. Cream preparations with a concentration of 7% show the best anti-aging effectiveness.
Edukasi Bahan Tambahan Pangan Pada UKM di Kota Medan Siti Maimunah; Alfi Sapitri; Dyna Grace Romatua Aruan; Andre Prayoga
Jurnal Pengabdian Masyarakat Mandira Cendikia Vol. 3 No. 8 (2024)
Publisher : YAYASAN PENDIDIKAN MANDIRA CENDIKIA

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Abstract

Bahan tambahan pangan (BTP) adalah bahan yang biasanya sengaja diberikan ke dalam makanan untuk menambah cita rasa, daya simpan lebih lama dan tidak memiliki nilai gizi. Lokasi pengabdian masyarakat dilakukan di Jl. Sei Petani No.9, Medan, yang dilaksanakan pada Juli 2024. Tujuan dalam pelaksanaan pengabdian masyarakat ini adalah untuk menginformasikan kepada UKM yang tergabung dalam komunitas APJI akan pentingnya mengetahui bahan tambahan Pangan (BTP) yang aman atau tidak dalam produksi bahan pangan. Metode pendekatan yaitu penyuluhan kepada UKM tentang bahan tambahan pangan. Pelaksanaan kegiatan diikuti 20 peserta, diskusi dan Tanya jawab selama penyuluhan. Hasil pengabdian masyarakat ini menunjukkan bahwa peserta di edukasi dengan harus terbiasa melihat label kemasan terutama bahan tambahan pangan yang akan dipakai ke produk mitra dengan melihat izin BPOM, masa kadaluarsanya, dan mencantumkannya di label kemasan produknya. 20% UKM belum terbiasa melihat label pada kemasan, 40% terbiasa membaca label dalam kemasan dan mencantumkan informasi di label pengemasan, dan semua tidak menggunakan bahan tambahan pangan melainkan denga perlakuan suhu dan fisik seperti proses pembekuan, pengasapan, pengerigan, pemberian gula dan garam dalam jumlah yang banyak. Kesimpulannya metode penyuluhan, edukasi, serta tanya jawab bisa memberikan motivasi kepada UKM dalam menambah informasi dan pengetauan peserta terhadap BTP yang aman, diperbolehkan dalam jumlah yang sudah di tentukan, dan bukan bahan BTP
Hematological and Biochemical Alterations of Andaliman (Zanthoxylum Acanthopodium Dc) with Doxorubicin Induced in White Wistar Rat Andre Prayoga; Aminah Dalimunthe; Zumaira; Emil Salim
International Journal of Ecophysiology Vol. 7 No. 1 (2025): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v7i1.20188

Abstract

Doxorubicin, a well-known chemotherapy drug, is associated with cardiac toxicity primarily due to oxidative stress. This oxidative stress leads to the production of reactive oxygen species and a subsequent decline in antioxidant levels. As doxorubicin induces the formation of free radicals and decreases endogenous antioxidants, it triggers various hematological and biochemical abnormalities. Consequently, the use of antioxidants has been proposed as a strategy to mitigate this damage. This study focuses on the administration of ethanol extract from Andaliman (EAF) fruit, recognized for its rich array of metabolites and antioxidant properties, which may serve as a cardioprotective agent against the adverse effects of doxorubicin. The research involved comprehensive observations, including hematological and clinical chemistry examinations. The findings indicate that EAF demonstrates protective effects by enhancing hematological and clinical chemistry parameters in male Wistar rats subjected to doxorubicin. Notably, these improvements were statistically significant when compared to the control group. Given its promising results, further exploration of EAF as a protective agent for hematological and biochemical health warrants attention and development.
Co-Authors Alfi Sapitri Aminah Dalimunthe Dyna Grace Romatua Aruan Emil Salim Riza Permata Dara Siti Maimunah Zumaira