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All Journal Jurnal Farmasi Galenika
Tita Nofianti
School of Pharmacy, STIKes Bakti Tunas Husada Tasikmalaya, Cilolohan street no 36 Tasikmalaya, Indonesia
Medicine & Pharmacology Public Health

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ANTIHYPERGLICEMIA ACTIVITY OF WATER FRACTION, ETHYL ACETATE FRACTION, AND N- HEXANE FRACTION OF SPINACH LEAVES EXTRACT (Amaranthus Cruentus L) ON MALE MICE SWISS Tita Nofianti
JURNAL FARMASI GALENIKA Vol 2 No 02 (2015): JURNAL FARMASI GALENIKA
Publisher : Universitas Bhakti Kencana

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Abstract

The activity test ofthe water fraction, ethyl acetate and n-hexane fraction of spinach leaves (Amaranthus cruentus L) has been conducted using the glucose tolerance method on male mice Swiss webster strain. The dose were water fraction 0.086 g/kg bw, ethyl acetate fraction 0.03g/kg body weight and n-hexane fraction 0.055 g/kg bw. Time measurement of blood glucose levels was conducted every 30 minutes for 120 minutes using a glucometer. The results showed that administration of water fraction, ethyl acetate fraction and n-hexane fraction of spinach leaves can lowering the blood glucose level of white male mice. While the best group that lowering the blood glucose level was ethyl acetate fraction 0,03 g/kg bw when compared to water fraction and n-hexane fraction. It can be concluded that spinach leaves showed antihyperglicemia.
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