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Gambaran Tingkat Pengetahuan Penggunaan Obat Tetrasiklin Tanpa Resep Dokter di Kelurahan Bangselok Kabupaten Sumenep Aldita Cahyani Puspitasari; N A Ashari Putri; Moch Rizal Ardiansyah; Rizdyana Firmaniar; Zakiyyah Qurrotul ‘Aini
Jurnal Indonesia Sehat Vol. 2 No. 3 (2023): JURINSE, Desember 2023
Publisher : SAMODRA ILMU: Lembaga Penelitian, Penerbitan, dan Jurnal Ilmiah

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Abstract

Background :  Lack of public understanding and knowledge regarding the correct and appropriate use of antibiotics is one of the factors that triggers antibiotic resistance. Tetracycline is the antibiotic most frequently used by the public. Based on its mechanism of action, tetracycline is included in the class of bacteriostatic antibiotics which work by inhibiting bacterial growth. Inappropriate use of tetracycline drugs can trigger resistance to tetracycline drugs. Purpose: The aim of this research is to  find out the level of knowledge about the use of tetracycline drugs purchased without a doctor's prescription in Bangselok sub-district. Method : This research was used the quantitative which is using the  observational study approach. Total  respondent were used in this are 98 peoples. Analysis in this study used descriptive. Result : there ware 55 respondent (56,1%) had good knowledge, 20  respondent (20,4 %) had sufficient knowledge, and 23 (23,5%) had lack of knowledge. Conclusion :  The level of community knowledge in Bangselok sub-district is good.
Analisis Efektivitas Kunyit Hitam (Curcuma caesia Roxb.) Dalam Penurunan Kadar Mikroalbumin dan Serum Kreatinin Pada Tikus Diabetes Nefropati Zakiyyah Qurrotu Aini; Tri Wijayanti; Aldita Cahyani Puspitasari
Jurnal Indonesia Sehat Vol. 3 No. 2 (2024): JURINSE, Agustus 2024
Publisher : SAMODRA ILMU: Lembaga Penelitian, Penerbitan, dan Jurnal Ilmiah

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Background: Diabetes mellitus (DM) is a chronic degenerative disease whose prevalence continues to increase. Treatment of DM with pharmacological therapy is often expensive and causes side effects. This study explores the effectiveness of black turmeric (Curcuma caesia Roxb.) in reducing complications of diabetic nephropathy by reducing microalbumin and creatinine. The purpose of this study was to analyze the effectiveness of black turmeric rhizome extract (Curcuma caesia Roxb.) in reducing serum creatinine and microalbumin levels in diabetic nephropathy model rats. Methods: This study used an in vivo method with rats induced with diabetes using STZ-NA and testing was carried out for 45 days. Serum creatinine and microalbumin were measured using a spectrophotometer and immunoturbidimetry. Results: This study showed that black turmeric extract at a dose of 400 mg/kg BW had an effectiveness equivalent to the positive control in reducing serum creatinine and microalbumin levels. The decrease in serum creatinine reached 20.10%, while the decrease in microalbumin reached 11.88%. The antioxidant and polyphenol content in black turmeric plays a role in reducing oxidative stress and inhibiting apoptosis in ? cells, which has an impact on reducing blood sugar levels and improving kidney function. Conclusion: Black turmeric extract (Curcuma caesia Roxb.) is effective in reducing serum creatinine and microalbumin levels in diabetic nephropathy model rats, with an optimal dose of 400 mg/kg BW. This study supports the potential of black turmeric as a natural therapeutic agent for diabetic nephropathy complications.
Hubungan Kepatuhan Minum Obat Anti Tuberkulosis Dengan Keberhasilan Pengobatan Tuberkulosis Pada Pasien Sensitif Obat Di Puskesmas Pamolokan Kabupaten Sumenep Hamlatul Jamiliyatil Istiqomah; Rizdyana Firmaniar; Zetiawan Trisno; Aldita Cahyani Puspitasari
Jurnal Farmasi & Sains Indonesia Vol 8 No 2 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no2p144-149

Abstract

Tuberculosis (TB) is a contagious infectious disease caused by the bacterium Mycobacterium Tuberculosis. Tuberculosis is transmitted through sputum or saliva containing tuberculosis bacilli. Tuberculosis is one of the world's health threats. The purpose of this study was to determine the relationship between adherence to taking anti-tuberculosis drugs and the success of tuberculosis treatment in drug-sensitive patients at the Pamolokan Health Center, Sumenep Regency. This study used a quantitative method with an observational survey approach using a Cross Sectional Research design. The population in this study were all drug sensitive tuberculosis patients undergoing treatment at the Pamolokan Health Center, Sumenep Regency in the January-June period, namely 32 people with total sampling techniques. The results of this study were 30 people as much as (93.75%) had compliant treatment compliance results. Based on the results of the study, it can be concluded that there is a relationship between adherence to taking medication with the success of anti-tuberculosis treatment. It is recommended that family members pay attention to sick family members, provide motivation, care, bring medical treatment and provide support to sick family members.