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Literatur Review: Gambaran Pengetahuan Masyarakat Mengenai Beyond Use Dates Obat Racikan Padat Non Steril Prascitasari, Ayu; Warditiani, Ni Kadek; Septiarini, Putu Ayudia; Permatasari, Ni Made Ayu Dinda; Ananda Putri, Ida Ayu Ngurah Trisna Noviani; Andika, Dewa Made Dwi; Candrayani, Komang Tri; Arkhania, Ni Putu Ayu Dhea; Sanjaya, Sadina Vania Tsany Dyah; Ariswari, Ni Kadek Putri; Nugrahaeni, Luh Gede Ratih Dewi Tri
Jurnal Farmasi Udayana Vol. 13, No. 1, Tahun 2024
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

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Abstract

Kurangnya pemahaman masyarakat terkait Beyond Use Date (BUD) disebabkan oleh minimnya informasi yang diberikan oleh tenaga kesehatan mengenai hal tersebut. BUD merupakan batas waktu obat bisa dikonsumsi setelah kemasan primernya dibuka. Metode yang digunakan dalam penyusunan artikel ini didasarkan pada Literatur Review mengenai penerapan Beyond Use Date (BUD) pada obat campuran padat non-sterile. Artikel yang dipilih telah memenuhi kriteria inklusi yang telah ditetapkan yaitu artikel yang terpublikasi pada tahun 2014-2024. Hasil yang diperoleh yaitu peningkatan pengetahuan masyarakat setelah diberikan sosialisasi terkait BUD tentang pengertian BUD, perbedaan BUD dan ED pada tablet, kapsul, obat racikan, dan non racikan. Sediaan padat harus memiliki BUD paling lambat sama dengan sisa waktu sampai tanggal kadaluarsa zat aktif terawal dalam sediaan atau 180 hari, dipilih yang paling singkat.
Phytochemical Profile and Hair Growth Activity of Marigold Flower (Tagetes erecta L.) Extract Puspitasari, Lia; Indrayoni, Putu; Septiarini, Putu Ayudia
Jurnal Pijar Mipa Vol. 21 No. 1 (2026)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i1.10388

Abstract

The Marygold flower (Tagetes erecta L.) exhibits numerous pharmacological properties. The marigold flower promotes hair development. Antioxidant substances that contribute to hair growth include alkaloids, flavonoids, tannins, and saponins. This research was conducted to determine the efficacy of ethanol extracts from Marygold flowers (Tagetes Erecta L.) as hair growers in male rabbits (Oryctolagus cuniculus). In a post-test-only control-group design, this study employed an experimental methodology. Thirty male rabbits served as test subjects in this study, which used one-way ANOVA. The KTL method was used in this study to determine the chemical constituent content of the ethanol extract of Marygold flowers at 5%, 10%, and 20% concentrations. Then, the length and density of the rabbit hair were measured to test the activity of hair growth. On days 7, 14, and 21, hair growth length was measured. On day 21, however, hair weight (density) was measured. Compounds from the flavonoid group (Rf 0.50 & 0.76), tannins (Rf 0.33 & 0.64), saponins (Rf 0.36 & 0.80), and alkaloids (Rf 0.33 & 0.62) were all positively present in the Marygold flower ethanol extract. The 20% concentration of Marygold flower ethanol extract exhibited the highest activity (p<0.05) in tests of hair density and length growth. The ethanol extract from Marygold flowers promotes hair growth in male rabbits, making their hair longer and denser.