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All Journal Jurnal Farmasi Udayana Jurnal Biologi Tropis Journal of Agritechnology and Food Processing
Permatasari, Ni Made Ayu Dinda
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

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Literatur Review: Gambaran Pengetahuan Masyarakat Mengenai Beyond Use Dates Obat Racikan Padat Non Steril Prascitasari, Ayu; Warditiani, Ni Kadek; Septiarini, Putu Ayudia; Permatasari, Ni Made Ayu Dinda; Ananda Putri, Ida Ayu Ngurah Trisna Noviani; Andika, Dewa Made Dwi; Candrayani, Komang Tri; Arkhania, Ni Putu Ayu Dhea; Sanjaya, Sadina Vania Tsany Dyah; Ariswari, Ni Kadek Putri; Nugrahaeni, Luh Gede Ratih Dewi Tri
Jurnal Farmasi Udayana Vol. 13, No. 1, Tahun 2024
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

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Abstract

Kurangnya pemahaman masyarakat terkait Beyond Use Date (BUD) disebabkan oleh minimnya informasi yang diberikan oleh tenaga kesehatan mengenai hal tersebut. BUD merupakan batas waktu obat bisa dikonsumsi setelah kemasan primernya dibuka. Metode yang digunakan dalam penyusunan artikel ini didasarkan pada Literatur Review mengenai penerapan Beyond Use Date (BUD) pada obat campuran padat non-sterile. Artikel yang dipilih telah memenuhi kriteria inklusi yang telah ditetapkan yaitu artikel yang terpublikasi pada tahun 2014-2024. Hasil yang diperoleh yaitu peningkatan pengetahuan masyarakat setelah diberikan sosialisasi terkait BUD tentang pengertian BUD, perbedaan BUD dan ED pada tablet, kapsul, obat racikan, dan non racikan. Sediaan padat harus memiliki BUD paling lambat sama dengan sisa waktu sampai tanggal kadaluarsa zat aktif terawal dalam sediaan atau 180 hari, dipilih yang paling singkat.
Penentuan Kualitas Minyak Goreng Bekas Setelah Penambahan Adsorben Alami dari Bonggol Jagung dan Ampas Tebu Permatasari, Ni Made Ayu Dinda; Hasanah, Nunung Uswatun; Setiawan, Wahyu Aldi; Diba, Asmara Yauma Putri Farah; Sahila, Dinda; Wulandari, Hesti; Muliasari, Handa
Journal of Agritechnology and Food Processing Vol 1, No 2 (2021)
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1523.553 KB) | DOI: 10.31764/jafp.v1i2.6973

Abstract

Continuous and repeated use of cooking oil at high temperatures accompanied by air and water contact can result in a hydrolysis reaction. The quality of the oil can be determined by carrying out the procedure for determining the free fatty acid content (FFA). Used cooking oil can be purified using an adsorbent/absorbent. Sugarcane bagasse and corn cobs have been widely used as adsorbents, but there has been no study comparing the increase in oil quality with these two adsorbents. This study aims to compare the color of the used cooking oil immersion with bagasse adsorbent and corncob charcoal adsorbent and determine the value of FFA levels of used cooking oil before and after soaking with bagasse adsorbent and corncob charcoal arsoben. The method used is fatty acid adsorption method and alkalimetric titration. From the observations, it was found that the color of the used cooking oil was fading after soaking with 3 types of adsorbents. The color of the immersion with a mixture of 1:1 adsorbent corncob charcoal and bagasse has the highest brightness level. FFA levels of used cooking oil after soaking also decreased from 0.207% to 0.141%; 0.132 %; and 0.094 %. The FFA content of used cooking oil by immersion in a 1:1 mixture of corn cob charcoal and bagasse was the lowest, which means the oil has the highest quality. It can be concluded that a mixture of 1:1 adsorbent of bagasse and corncob charcoal is the best adsorbent.
Anti-Radical Activity Test of Fractions from Ashitaba Herbs (Angelica keiskei) Permatasari, Ni Made Ayu Dinda; Muliasari, Handa; Hanifa, Nisa Isneni; Hidayati, Agriana Rosmalina; Hidajat, Dedianto; Hajrin, Wahida; Rizkika, Adila
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7638

Abstract

Acne vulgaris is a chronic inflammation of the skin’s pilosebaceous unit, caused by oxidative stress due to reactive oxygen species (ROS) release. Oxidative stress conditions can be treated using natural antioxidants, namely ashitaba (Angelica keiskei). In contrast to previous studies that tested column chromatography fraction of the macerated ethanol extract, this study examined the liquid-liquid partition fraction of 80% methanol sonicated extract of Ashitaba herb. This study aims to determine the antiradical activity of various fractions of Ashitaba herb extract against 1,1-diphenyl-2-picrylhidrazyl (DPPH) free radicals. 80% methanol extract of the Ashitaba herb was fractionated using chloroform, ethyl acetate, and water solvents. Each ashitaba herb fraction was identified for the content of flavonoids and phenolic compounds and the antiradical DPPH activity was tested with ascorbic acid standard using a UV-Vis spectrophotometer. The IC50 value of each fraction was statistically analyzed using One-Way ANOVA and Posthoc Tukey. The results of phytochemical identification showed that ashitaba herb fractions positively contain flavonoids and phenolics. Antiradical activity of the chloroform, ethyl acetate, and water fractions against DPPH was indicated by IC50 values of 164.22±5.68 ppm (moderate); 8.70±0.12 ppm (very strong); and 243.60±8.14 ppm (weak). Statistically, each ashitaba herb fraction differed significantly from ascorbic acid (IC50 2.37±0.05 ppm). The ethyl acetate fraction has the strongest antioxidant activity and is in the same category of antioxidant strength as the ascorbic acid standard.
Co-Authors Ananda Putri, Ida Ayu Ngurah Trisna Noviani Andika, Dewa Made Dwi Ariswari, Ni Kadek Putri Arkhania, Ni Putu Ayu Dhea Candrayani, Komang Tri Dedianto Hidajat Diba, Asmara Yauma Putri Farah Hajrin, Wahida Hasanah, Nunung Uswatun Hesti Wulandari Hidayati, Agriana Rosmalina Muliasari, Handa Ni Kadek Warditiani Nisa Isneni Hanifa Nugrahaeni, Luh Gede Ratih Dewi Tri Prascitasari, Ayu Rizkika, Adila Sahila, Dinda Sanjaya, Sadina Vania Tsany Dyah Septiarini, Putu Ayudia Setiawan, Wahyu Aldi