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Studi Penggunaan Antihipertensi Golongan Angiotensin Reseptor Blocker (ARB) pada Pasien Chronic Kidney Disease (Penelitian dilakukan di RS Universitas Muhammadiyah Malang) Nurfausiah, Nurfausiah; Hasmono, Didik; Kusumaningtyas, Atika Putri; Syifa', Nailis
JFM (Jurnal Farmasi Malahayati) Vol 7, No 2 (2024)
Publisher : Jurnal Farmasi Malahayati (JFM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jfm.v7i2.15903

Abstract

Hypertension and chronic kidney disease (CKD) are interrelated pathophysiological conditions, where sustained hypertension can lead the deterioration of renal function, and progressive deterioration of renal function can conversely result in poorer blood pressure (BP) control. Antihypertensives are given to CKD patients with the goal of lowering their blood pressure to < 140 mmHg and preventing harm to other organs. Angiotensin Receptor Blockers (ARB) are one of the first line of therapy used to reduce blood pressure in CKD patients. The research purpose was to determine the pattern of ARB regarding the type, dosage form, combination, and route of the group given to CKD patients at UMM’s General Hospital. Research was conducted in observational research with a descriptive nature and retrospective data collection on the health medical record of CKD with period January – Desember 2022. Results of the research showed that patients who met the inclusion criteria amounted to 25 patients using ARB antihypertensive therapy, the highest number of gender 52% male and 48% female, at the age of 46-55 years. The most common single use was Candesartan (1x16mg)po (5%) 2 patients, the most common combination II was Candesartan (1x16mg)po + Furosemide (3x40mg) iv 7 patients (18%), the most common combination III was Candesartan (1x16mg)po + Amlodipine (1x10mg)v + Furosemide (3x40mg)iv, the most common combination IV was Candesartan (1x16mg)po + Amlodipine (1x10mg)po + Clonidine (3x0.15mg)po + Furosemide (3x40mg)iv. There was a switch pattern as many as 13 samples (52%). Most patients met the blood pressure target at ≤ 140 mmHg.
Perilaku Hidup Bersih dan Sehat sebagai Langkah Pencegahan Diare pada Siswa Sekolah Dasar Syifa', Nailis; Wardana, Regita Pramesty Cahya; Wulandari, Putri Teky; Ariesta, Rossa; Rahmawati, Fina Eka; Ifada, Baiq Nurhaliza; Muhammad, Izbikavik
AJAD : Jurnal Pengabdian kepada Masyarakat Vol. 3 No. 3 (2023): DECEMBER 2023
Publisher : Lembaga Mitra Solusi Teknologi Informasi (L-MSTI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59431/ajad.v3i3.209

Abstract

PHBS is a set of behaviors that are practiced based on awareness as an effort to be healthy and actively help the health of the surrounding environment. Clean and Healthy Behavior at an early age is important to maintain personal and environmental health. Early childhood is also susceptible to infectious diseases such as flu and diarrhea if they do not maintain personal and surrounding hygiene. Diarrheal disease is often considered a trivial matter but if it is not addressed it can result in quite serious matters. Therefore, we conducted community services which aims to provide students’ knowledge and understanding about Clean and Healthy Behavior and diarrheal diseases which often attack children at Muhammadiyah 1 Malang Elementary School students. The implementation method is carried out by counseling using power point media and videos. In the initial activity, a question-and-answer session was carried out, then giving educational material, showing educational videos, then evaluating it with a posttest.
Studi Penggunaan Natrium Bikarbonat pada Pasien Penyakit Ginjal Kronik dengan Asidosis Metabolik Andilusia, Sindy; Hasmono, Didik; Kusumaningtyas, Atika Putri; Syifa', Nailis
Jurnal Farmasi & Sains Indonesia Vol 7 No 2 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no2p100-105

Abstract

Chronic Kidney Disease (CKD) is defined as a condition in which there are abnormalities in kidney performance, and occurs for at least 3 months. Metabolic acidosis is a disturbance of acid-base balance resulting in a decrease in plasma sodium bicarbonate concentration with a decrease in blood pH. Metabolic acidosis patients are characterized by (arterial pH <7.35, PCO2 <35 mmHg, and HCO3- <22 mEq/L [mmol/L]). Sodium bicarbonate increases plasma bicarbonate, and increases blood pH. This study aims to identify the pattern of sodium bicarbonate use in CKD patients who experience metabolic acidosis including type, dose, route, interval, and duration of drug administration at Universitas Muhammadiyah Malang Hospital. This study was conducted in the form of observational research by analyzing descriptively and retrospectively collecting data using Health Record data of patients who underwent hospitalization in the period 01 January 2022 – 31 December 2022. Based on the research that has been carried out, it is concluded that patients who meet the therapeutic targets are 23 patients (96%), indicated by the pattern of sodium bicarbonate use only used singly in all CKD patients with metabolic acidosis as many as 24 patients (100%), the most dose is (3x500mg) po as many as 20 patients (83%), with a duration of administration ≤ 5 days as many as 19 patients (79%). The suggestions that researchers convey are research that has been carried out, can be used as a reference and further guidance.