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Prothrombin Complex Concentrate as a Key Adjunct in Massive Hemorrhage Management in Placenta Accreta Spectrum Disorder: A Case Report Pramana, Putu Bagus Gin Gin; Tjokorda Gde Agung Senapathi; Pontisomaya Parami; Tjahya Aryasa
Archives of The Medicine and Case Reports Vol. 5 No. 3 (2024): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v5i3.599

Abstract

Placenta accreta spectrum disorder (PASD) is a severe obstetric complication associated with significant hemorrhage risk. This report highlights the successful use of prothrombin complex concentrate (PCC) as part of a multidisciplinary approach to managing a case of massive hemorrhage in PASD. A 36-year-old woman, G3P2002, at 33 weeks gestation, diagnosed with placenta previa totalis and suspected PASD, underwent a planned cesarean hysterectomy. The surgery was complicated by 5200 mL hemorrhage due to placental invasion and bladder injury. Hemodynamic instability was managed with massive transfusion protocol activation, including PCC, tranexamic acid, and packed red blood cells. Intra-abdominal packing was performed for hemostasis, and the bladder injury was repaired. Continued PCC administration in the ICU, along with other supportive measures, resulted in hemorrhage control and stabilization. The patient was successfully extubated and discharged after a second surgery to remove packing. This case emphasizes the vital role of PCC in the multidisciplinary management of massive hemorrhage in PASD. Early recognition of PASD risk factors and prompt intervention, including PCC administration, are crucial for optimal maternal outcomes.
Overview of Acute Kidney Injury (AKI) in the Intensive Care Unit: Observational Study at Prof. Dr. I.G.N.G Ngoerah General Hospital, Denpasar, Indonesia Pontisomaya Parami; Tjokorda Gde Agung Senapathi; Gede Wirya Kusuma Duarsa; Pramana, Putu Bagus Gin Gin
Journal of Anesthesiology and Clinical Research Vol. 5 No. 3 (2024): Journal of Anesthesiology and Clinical Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/jacr.v5i3.555

Abstract

Introduction: Acute kidney injury (AKI) is a serious clinical syndrome with complications that can be life-threatening. AKI is associated with increased length of stay and mortality in patients in the intensive care unit (ICU). This study aims to determine the incidence and characteristics of AKI in ICU patients at Prof. Dr. I.G.N.G Ngoerah General Hospital Denpasar. Methods: This descriptive observational research was conducted by collecting data from medical records of ICU patients for three months. Data were analyzed to determine the incidence of AKI, stage of severity, and mortality rate. Results: Of the 388 patients treated in the ICU, 87 (22.37%) experienced AKI. The mortality rate in AKI patients was 12.9% (n=50). A total of 11.05% (n=25) of AKI patients were classified as stage 1, 5.91% (n=17) as stage 2, and 5.40% (n=8) as stage 3. Conclusion: The incidence of AKI in the ICU of Prof. Dr. I.G.N.G Ngoerah General Hospital Denpasar. is quite high (22.37%). AKI is associated with a significant mortality rate (12.9%). This study provides a preliminary description of the incidence and characteristics of AKI in the ICU of this hospital, which may be useful for improving the quality of patient care and prevention of AKI.