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All Journal CHEESA: Chemical Engineering Research Articles Jurnal Mandala Pharmacon Indonesia Indonesian Journal of Medical and Pharmaceutical Science
Suryani, Arman
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Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Nanoparticles and Nanoliposomes for Hair Growth Serum Arismunandar, Arif; Chabib, Lutfi; Ramadani, Arba Pramundita; Suryani, Arman; Kamarulzaman, Ezatul Ezleen
CHEESA: Chemical Engineering Research Articles Vol. 7 No. 1 (2024)
Publisher : Universitas PGRI Madiun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25273/cheesa.v7i1.19908.57-66

Abstract

Solubility in penetrating the follicles is the main obstacle in the formulation of hair growth serum preparation with chemicals derived from natural or synthetic materials. Therefore, a delivery system is needed to deliver more chemical compounds into the follicles. Nanoparticles and nanoliposomes are potential chemical compound delivery systems in hair growth serum. Specifically, nanoparticles with a particle size of less than 200 nm can increase the transport of serum chemical compounds into the scalp. The small particle size makes the interaction between atoms and molecules faster and prevents clumping with the repulsive force of dispersed particles. Meanwhile, nanoliposomes with lipids as encapsulation in the delivery of lipophilic or hydrophilic chemical compounds with nanosizes can significantly increase serum diffusion on the scalp.
Formulasi Hand & Body Lotion dengan Minyak Biji Tomat (Solanum lycopersicum L.): Studi Inovatif Pelembab dan Antioksidan untuk Perawatan Kulit Suryani, Arman; Wahyuni, Tri
Indonesian Journal of Medical and Pharmaceutical Science Vol. 4 No. 1 (2025)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v4i1.370

Abstract

Background: Exposure to free radicals can cause premature ageing, dryness, and damage to the skin. Tomato seed oil (Solanum lycopersicum L.) contains antioxidants, such as lycopene and essential fatty acids, potentially protecting the skin from oxidative stress. This study aims to develop a hand & body lotion formulation made from tomato seed oil as an innovation in skin care. Methods: This study was experimental and conducted by testing lotion formulations containing tomato seed oil. The products were tested using various parameters, including organoleptic test, homogeneity, viscosity, pH, adhesion, spreadability, antioxidant activity, and moisture. Results: The formulated hand & body lotion has a white colour, rose oil aroma, and thick texture. The homogeneity test showed consistent results, indicating a stable formulation. The lotion had a viscosity of 3408.7 ± 6.3 Cp, pH of 5.7 ± 0.2, spreadability of 15.1 ± 1.0 cm, and stickiness of 4.1 ± 0.1 seconds. The antioxidant activity IC50 was recorded at 18.03 ppm, and the treatment proved to significantly increase moisture, with significant differences on days 0, 3, and 7 (p<0.001), indicating the effectiveness and stability of the effect. Conclusion: Tomato seed oil-based hand & body lotion shows potential as an innovative product with antioxidant and moisturizing benefits. This formulation has good physical characteristics, maintains stability, is safe to use, and is well accepted.
Formulation Optimization and Antibacterial Activity of Citronella (Cymbopogon nardus (L.) Rendle) Topical Gel Spray Against Staphylococcus aureus Using a Simplex Lattice Design Rajab, Muhammad Andy; Putri, Chintiana Nindya; Suryani, Arman; Salamah, Nina
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 2 (2025): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i2.867

Abstract

Atopic dermatitis is skin inflammation in the form of dermatitis caused by Staphylococcus aureus bacterial infection. Citronella essential oil has the potential as an active ingredient in spray gel preparations to help overcome atopic dermatitis due to Staphylococcus aureus bacterial infection. The aim is to determine the optimal spray gel formula from citronella essential oil (Cymbopogon nardus (L.) Rendle) and antibacterial activity against Staphylococcus aureus bacteria. The methods material optimized are Na-CMC, Propylene glycol, and tween 20. Evaluation of the preparation in the form of organoleptic tests, homogeneity, pH, viscosity, drying time, spraying patterns, yeast mold numbers using the spread plate method, and antibacterial activity against Staphylococcus aureus bacteria using the good diffusion method. The results of the concentration of Na-CMC: Propylene glycol: Tween 20 (0.27: 4.72: 10) produced an optimal preparation formula. The spray gel is milky white, has a distinctive lemongrass odor, and is slightly thick. The spray gel is homogeneous with a pH of 4.94 ± 0.16, a viscosity of 76.73 ± 7.01 cPs, and a drying time of 3.60 ± 0.40 minutes. The mold/yeast count test showed that the spray gel was free from mold/yeast contamination and was stable at storage temperatures of 4?C and 40?C. The results of antibacterial activity were able to inhibit Staphylococcus aureus bacteria with an inhibition zone diameter of 6.85 mm ± 2.80. Conclusion: Na-CMC concentration of 0.27%, Propylene Glycol concentration of 4.72%, and Tween 20 concentration of 10% produced optimal spray gel and inhibited Staphylococcus aureus.
Co-Authors Arba Pramundita Ramadani Arismunandar, Arif Kamarulzaman, Ezatul Ezleen Lutfi Chabib, Lutfi Nina Salamah Putri, Chintiana Nindya Rajab, Muhammad Andy tri wahyuni