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All Journal CHEESA: Chemical Engineering Research Articles Indonesian Journal of Medical and Pharmaceutical Science
Suryani, Arman
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Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Nanoparticles and Nanoliposomes for Hair Growth Serum Arismunandar, Arif; Chabib, Lutfi; Ramadani, Arba Pramundita; Suryani, Arman; Kamarulzaman, Ezatul Ezleen
CHEESA: Chemical Engineering Research Articles Vol. 7 No. 1 (2024)
Publisher : Universitas PGRI Madiun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25273/cheesa.v7i1.19908.57-66

Abstract

Solubility in penetrating the follicles is the main obstacle in the formulation of hair growth serum preparation with chemicals derived from natural or synthetic materials. Therefore, a delivery system is needed to deliver more chemical compounds into the follicles. Nanoparticles and nanoliposomes are potential chemical compound delivery systems in hair growth serum. Specifically, nanoparticles with a particle size of less than 200 nm can increase the transport of serum chemical compounds into the scalp. The small particle size makes the interaction between atoms and molecules faster and prevents clumping with the repulsive force of dispersed particles. Meanwhile, nanoliposomes with lipids as encapsulation in the delivery of lipophilic or hydrophilic chemical compounds with nanosizes can significantly increase serum diffusion on the scalp.
Formulasi Hand & Body Lotion dengan Minyak Biji Tomat (Solanum lycopersicum L.): Studi Inovatif Pelembab dan Antioksidan untuk Perawatan Kulit Suryani, Arman; Wahyuni, Tri
Indonesian Journal of Medical and Pharmaceutical Science Vol. 4 No. 1 (2025)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v4i1.370

Abstract

Background: Exposure to free radicals can cause premature ageing, dryness, and damage to the skin. Tomato seed oil (Solanum lycopersicum L.) contains antioxidants, such as lycopene and essential fatty acids, potentially protecting the skin from oxidative stress. This study aims to develop a hand & body lotion formulation made from tomato seed oil as an innovation in skin care. Methods: This study was experimental and conducted by testing lotion formulations containing tomato seed oil. The products were tested using various parameters, including organoleptic test, homogeneity, viscosity, pH, adhesion, spreadability, antioxidant activity, and moisture. Results: The formulated hand & body lotion has a white colour, rose oil aroma, and thick texture. The homogeneity test showed consistent results, indicating a stable formulation. The lotion had a viscosity of 3408.7 ± 6.3 Cp, pH of 5.7 ± 0.2, spreadability of 15.1 ± 1.0 cm, and stickiness of 4.1 ± 0.1 seconds. The antioxidant activity IC50 was recorded at 18.03 ppm, and the treatment proved to significantly increase moisture, with significant differences on days 0, 3, and 7 (p<0.001), indicating the effectiveness and stability of the effect. Conclusion: Tomato seed oil-based hand & body lotion shows potential as an innovative product with antioxidant and moisturizing benefits. This formulation has good physical characteristics, maintains stability, is safe to use, and is well accepted.
Co-Authors Arba Pramundita Ramadani Arismunandar, Arif Kamarulzaman, Ezatul Ezleen Lutfi Chabib, Lutfi tri wahyuni