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All Journal IDJP (Indonesian Journal of Pharmaceutics) Majalah Farmasetika
Sylvia Nurrasjid, Evi
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Medicine & Pharmacology

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Penerapan Lean Warehousing Pada Gudang Bahan Baku Industri Farmasi PT XYZ Diina, Tresnafuty Rasyiida; Sriwidodo, Sriwidodo; Sylvia Nurrasjid, Evi; Kustiyawan, Iwa
Majalah Farmasetika Vol 9, No 4 (2024)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v9i4.54864

Abstract

Persaingan di dunia Industri pada era modern ini memicu para perusahaan untuk meningkatkan daya saing dan kualitas produk sebagai pemenuhan kepuasan pelanggan. Gudang dalam Industri Farmasi berperan dalam menjaga keberhasilan dan kelancaran rantai pasok produk. Setiap aktivitas yang dilakukan di gudang merupakan hal yang sangat penting bagi Industri Farmasi terutama pada aspek penyimpanan dan pengiriman. Gudang bahan baku merupakan tempat penyimpanan bahan baku yang akan digunakan untuk proses produksi, maka dari itu pengelolaan barang persediaan yang tidak efektif dan efisien dapat dilihat dari adanya pemborosan atau waste pada proses di gudang. Penelitian ini bertujuan untuk meningkatkan efisiensi aktivitas pergudangan melalui identifikasi pemborosan (waste) pada kegiatan di gudang bahan baku. Penelitian dilakukan menggunakan tool Value Stream Mapping dan Process Activity Mapping. Setelah waste teridentifikasi, maka tahapan selanjutnya adalah mencari akar permasalahan menggunakan fishbone diagram untuk selanjutnya dibuat rencana usulan perbaikan berupa Future Value Stream Mapping. Diketahui waste yang dominan terjadi adalah waiting dan motion. Usulan perbaikan yang dapat dilakukan yaitu dengan melengkapi informasi dimensi lokasi penyimpanan pada sistem ERP serta peningkatan kesadaran operator dalam menerapkan SOP. 
Tableting Turmeric Rhizome (Curcuma domestica Val.) and Mangosteen Peel (Garcinia mangostana L.) Extract as Antioxidant Supplement Reyhani, Amalia; Sriwidodo, Sriwidodo; Chaerunisa, Anis Yohana; Umar, Abd. Kakhar; Sylvia Nurrasjid, Evi; Rahman Roestan, Mas
Indonesian Journal of Pharmaceutics Vol 4, Issue 3, Sep - November, 2022
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v4i3.39667

Abstract

Free radicals are unstable molecules that lose electrons in their outer orbitals. These compounds can be toxins for the human body and cause various degenerative diseases. To avoid this, we need antioxidants. Examples of common sources of antioxidants are turmeric (Curcuma domestica Val.) and mangosteen rind (Garcinia mangostana L.). Both of these plants have very strong antioxidant activity but have a less favorable taste for consumption. This study aimed to obtain tablets containing turmeric rhizome and mangosteen rind extract that can cover the taste with a variety of binders. Subsequently, we observed the antioxidant  activity of two extracts before and after preparation. The tableting method was wet granulation and the characterization included the physical properties of the tablets. The levels of curcumin, alpha mangosteen, and total polyphenols were also checked. The antioxidant activity was measured using the DPPH method. Based on the characterization results, NaCMC 5% was the best binder for preparing tablets containing turmeric rhizome and mangosteen rind extract with a flow rate of 11.434 g/s, repose’s angle of 29.39ᵒ, loss on drying of 2.65%, carr’s index of 15.22, hardness of 43N, friability of 0.926%, and disintegration time of 16.44 minutes. The antioxidant test result showed that the combination of turmeric extract and mangosteen rind extract with a ratio of 1:2 had the best antioxidant activity with an IC50 value of 31.01 µg/ml, alpha mangosteen level of 29.77%, and curcumin level of 27.22%. The antioxidant activity of the preparation was not changed significantly after tableting. Based on the findings, it can be concluded that the tablet formulation of turmeric rhizome and mangosteen rind extract using 5% NaCMC can be potentially used as an antioxidant supplement.
Co-Authors CHAERUNISA, ANIS YOHANA Diina, Tresnafuty Rasyiida Kustiyawan, Iwa Rahman Roestan, Mas Reyhani, Amalia Sriwidodo Sriwidodo, Sriwidodo Umar, Abd. Kakhar