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All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research The International Journal of Medical Science and Health Research
Anak Agung Made Sucipta
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Correlation Between APGAR Scores and the Incidence of Hyperbilirubinemia in Neonates at Wangaya Regional General Hospital, Denpasar Putri Widyastiti, Ni Nyoman; I Wayan Bikin Suryawan; Anak Agung Made Sucipta
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 5 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i5.995

Abstract

Background: Hyperbilirubinemia is defined as total serum bilirubin level at ≥ 5 mg/dl. In Indonesia, the prevalence of jaundice is 13,7-85%. One of the risk factors for hyperbilirubinemia in neonates is babies born with a history of asphyxia. The diagnosis of asphyxia can be enforced by the APGAR scoring system. This study aims to determine the relationship between APGAR values and the incidence of hyperbilirubinemia in neonates treated at Wangaya Regional General Hospital. Methods: This research is an analytic observational study using a cross-sectional approach, which was carried out in April-May 2022. The sample was taken by consecutive sampling. Bivariate analysis was performed using the chi-square test. Confounding variables will be controlled by design and by analysis. Influential risk factors were analyzed multivariate with logistic regression. Data were analyzed with SPSS software. Results: From 84 samples, 67, 9% had hyperbilirubinemia. The 1-minute APGAR score (P = 0,017, OR = 8,373, 95% CI; 1,468 – 47,738) and the 5-minute APGAR score (P = 0,034, OR =8,680, 95% CI; 1,172 – 64, 293) had significant correlation with the incidence of hyperbilirubinemia in neonates treated at Wangaya Regional General Hospital. Conclusion: Low APGAR scores have a significant correlation with the incidence of hyperbilirubinemia in neonates treated at Wangaya Regional General Hospital. The factor that most influences the incidence of hyperbilirubinemia is the 1-minute APGAR score. Neonates born with a low 1-minute APGAR score are 8,3 times at risk of experiencing hyperbilirubinemia.
Massive Pleural Effusion in Tuberculosis Due to Systemic Lupus Erythematosus: A Case Report Anthony Tjajaindra; Veronica Winda Soesanto; Anak Agung Made Sucipta
The International Journal of Medical Science and Health Research Vol. 13 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/wy3xjh07

Abstract

Introduction : Tuberculosis (TB) posed a significant risk for mortality and morbidity in autoimmune disorders like systemic lupus erythematosus (SLE). TB in SLE patients often manifests as extrapulmonary disease, affecting areas like the pleura, leading to pleuritis and effusion. This case report aims to assess a case of massive pleural effusion in tuberculosis patient due to co-existing SLE. Case Description : We present the case of a 17 y.o. girl who experienced progressive shortness of breath, worsening one day prior to her admission to the Emergency Department of Wangaya Regional General Hospital. Examination indicated a massive pleural effusion. Pleural drainage was performed the following day, yielding a total of 2,800 mL of pleural fluid. Further examination revealed symptoms of SLE, strengthen by family history. A positive antinuclear antibody (ANA) test confirmed the diagnosis of SLE. Patient then given pulse intravenous methylprednisolone at dose of 600 mg once a day for three days and antituberculosis Fixed-Dose Combination therapy. After the effusion resolved, patient had outpatient treatment and control periodically.  Conclusion : The increased risk of tuberculosis in SLE individual linked to immunological abnormalities in SLE, which hampers the body’s ability to control TB infection. Suspecting of SLE in patients with massive pleural effusion can lead to prompt treatment.
Correlation Between APGAR Scores and the Incidence of Hyperbilirubinemia in Neonates at Wangaya Regional General Hospital, Denpasar Putri Widyastiti, Ni Nyoman; I Wayan Bikin Suryawan; Anak Agung Made Sucipta
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 5 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i5.995

Abstract

Background: Hyperbilirubinemia is defined as total serum bilirubin level at ≥ 5 mg/dl. In Indonesia, the prevalence of jaundice is 13,7-85%. One of the risk factors for hyperbilirubinemia in neonates is babies born with a history of asphyxia. The diagnosis of asphyxia can be enforced by the APGAR scoring system. This study aims to determine the relationship between APGAR values and the incidence of hyperbilirubinemia in neonates treated at Wangaya Regional General Hospital. Methods: This research is an analytic observational study using a cross-sectional approach, which was carried out in April-May 2022. The sample was taken by consecutive sampling. Bivariate analysis was performed using the chi-square test. Confounding variables will be controlled by design and by analysis. Influential risk factors were analyzed multivariate with logistic regression. Data were analyzed with SPSS software. Results: From 84 samples, 67, 9% had hyperbilirubinemia. The 1-minute APGAR score (P = 0,017, OR = 8,373, 95% CI; 1,468 – 47,738) and the 5-minute APGAR score (P = 0,034, OR =8,680, 95% CI; 1,172 – 64, 293) had significant correlation with the incidence of hyperbilirubinemia in neonates treated at Wangaya Regional General Hospital. Conclusion: Low APGAR scores have a significant correlation with the incidence of hyperbilirubinemia in neonates treated at Wangaya Regional General Hospital. The factor that most influences the incidence of hyperbilirubinemia is the 1-minute APGAR score. Neonates born with a low 1-minute APGAR score are 8,3 times at risk of experiencing hyperbilirubinemia.
Co-Authors Anthony Tjajaindra I Wayan Bikin Suryawan Putri Widyastiti, Ni Nyoman Veronica Winda Soesanto