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All Journal Paediatrica Indonesiana Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Ophthalmologica Indonesiana
Amiruddin, Primawita Oktarima
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Health Professions Medicine & Pharmacology Public Health

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Clinical characteristics, management, and survival of retinoblastoma patients: a five-year study at an Indonesian tertiary eye hospital Putri, Aliya Numasari; Kuntorini, Maya Sari Wahyu; Amiruddin, Primawita Oktarima
Paediatrica Indonesiana Vol. 64 No. 4 (2024): July 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.4.2024.311-7

Abstract

Background Studies on the clinical characteristics of retinoblastoma in Indonesia have been limited, even though retinoblastoma is the most common pediatric ocular malignancy worldwide and the second-most common pediatric malignancy in Indonesia. The estimated patient survival rate in lower-middle-income countries is 77%, and survival is highly dependent on early diagnosis and therapy. Objective To identify the clinical characteristics of retinoblastoma in patients at the Cicendo National Eye Hospital, as an Indonesian tertiary eye hospital. Methods This retrospective, observational study included pediatric patients <18 years of age diagnosed with retinoblastoma at the Cicendo National Eye Hospital, Bandung, West Java, between January 2018 and December 2022. We collected patients’ medical record data on age, gender, laterality, chief complaints, stage of disease, grouping, histopathologic features, therapy, and survival. Results Of 247 retinoblastoma patients (328 eyes) enrolled, 53.85% presented at 1-2 years of age and 50.61% were males. Patients mostly presented with unilateral (67.21%) retinoblastoma, leukocoria (51.82%) as the chief complaint, and classified as International Retinoblastoma Staging System (IRSS) stage III (33.20%). Tumors were mostly intraocular (58.84%), particularly group E (39.02%). Most tumors showed undifferentiated (45.43%) and high-risk features (54.27%). Most eyes were treated with combination therapy (74.09%), particularly local and systemic therapy (59.45%). Survival was noted at 18.62% of patients, but 62.75% of patients were lost to follow-up. Conclusion Most patients present with advanced retinoblastoma. Most histopathological results shows undifferentiated and high-risk features of the tumor. Delays in diagnosis and therapy may occur due to a lack of awareness and knowledge regarding clinical manifestations of retinoblastoma, which leads to worse prognosis.
Clinical Characteristics and Management of Pediatric Eye Trauma in National Tertiary Eye Hospital in Indonesia Axa, Alya Putri; Amiruddin, Primawita Oktarima; Caesarya, Sesy
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 2 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i2.9087

Abstract

Eye trauma is a major cause of vision problems in children, leading to visual impairment and blindness. This issue has significant global implications, affecting children psychologically and socially. According to the American Academy of Pediatrics, 66% of all eye traumas occur in individuals under 16, with the highest occurrence between ages 9 and 11. We conducted a retrospective descriptive study using medical records of pediatric patients aged 0 - 18 years who experienced eye trauma from January to December 2022 at the National Eye Center-Cicendo Eye Hospital. There were 190 patients included in this study. The majority of patients were male (69.47%) and the most common age group affected was 6 - 12 years (33.16%). Leading causes of eye trauma were blunt trauma (58.95%). The common management for eye trauma in this study is operative or medical procedures (67,37%) This study provides valuable information on the characteristics and management of eye trauma in children, which can contribute to the development of prevention strategies and appropriate interventions. Understanding the patterns of eye trauma and implementing comprehensive care can help prevent blindness and minimize visual impairment. Keywords: Eye Trauma; Children; Management
Refractive and Visual Outcomes of Pediatric Cataract Surgery in Indonesian Tertiary Eye Center Memed, Feti Karfiati; Santosa, Rizki Adi; Irfani, Irawati; Caesarya, Sesy; Amiruddin, Primawita Oktarima; Kuntorini, Mayasari Wahyu
Majalah Oftalmologi Indonesia Vol 51 No 2 (2025): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v51i2.101763

Abstract

Introduction: Cataract remains as a leading cause of visual impairment in children. Surgical intervention and post-operative refractive correction remain fundamental. This study aims to describe the refractive and visual outcome of pediatric cataract surgery in a tertiary eye center in Indonesia.   Methods: This retrospective study was conducted utilizing medical records of all congenital and developmental cataracts patients undergoing cataract extraction procedures with or without primary IOL implantation between January and December 2022. Exclusion criteria included patients who did not undergo visual acuity and objective refraction examination 1-month post-cataract surgery and those with incomplete medical records data.   Results: A total of 118 eyes from 65 patients was included in this study. Most patients had bilateral cataracts (93.80%) and operated at the median age of 18 (0.96-212.64) months. Post-operatively, there were 71 (60.19%) aphakic and 47 (39.81%) pseudophakic patients with a respective refractive status of +18.00 (12.00 – 21.13) D and +0.60 (±2.37) D. Prediction error (PE) and absolute prediction error (APE) were obtained within 1.00 D. Most aphakic patients had unquantifiable visual acuity both before (91.50%) and after (83%) surgery. Among pseudophakic patients, nine (19.16%) had visual acuity of ≥ 6/12 and seven (14.89%) had visual acuity of <6/12 - 6/18 post-operatively. No patients had visual acuity ≥ 6/12 and <6/12 - 6/18 before surgery.   Conclusion: Post-operative refractive status of both aphakic and pseudophakic patients were well within correctable range. There was an improvement of vision after surgery. Limited visual potential may be attributed to the presence of amblyopia.
Prevalence of Visual Impairment Among School Children in Lengkong Subdistrict Bandung Rachmawati, Dinta; Raden Roro, Annisa Wahyuni Ratnasari; Amiruddin, Primawita Oktarima
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 19 No 1 (2025): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan (In Press)
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v19i1.10640

Abstract

Visual impairment in children still becomes a burden globally. It can affect children’s learning process, career options, and psychosocial development eventually. This study aims to determine the prevalence of visual impairment among schoolchildren in Lengkong Subdistrict, Bandung. This was a retrospective descriptive study using secondary data from visual impairment screening program of schoolchildren aged 6-14 years, which was conducted by Health Promotion Unit of Bandung Eye Center Hospital from August to November 2023. The sample for this study was collected using a total sampling technique. A total of 907 data consisting of Uncorrected Visual Acuity (UCVA), Presenting Visual Acuity (PVA), age, and gender were collected and analysed using Microsoft Excel 2019. The prevalence of visual impairment in schoolchildren was 16.2% with UCVA and 11.1% with PVA, moderate visual impairment was the major classification. Female students were more likely to have visual impairment compared to male students. The highest number of visual impairments with UCVA and PVA compared to age distribution was 12 years old. These results need to become school and government’s concern to create further policy regarding children’s eye health to support an optimal learning process.
CHALLENGES IN THE SURGICAL MANAGEMENT OF BILATERAL POSTERIOR LENTIGLOBUS: Poster Presentation - Case Report - Resident RAHMANI, SYIFA; Memed, Feti Karfiati; Caesarya, Sesy; Amiruddin, Primawita Oktarima; Irfani, Irawati; Kuntorini, Mayasari Wahyu
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/awdxnd05

Abstract

Introduction : Lentiglobus is a lens deformation characterized by spherical bulging of the lens surface. The weakness of the posterior capsule in the lentiglobus makes the surgery challenging. We present a case of bilateral posterior lentiglobus and its management. Case Illustration : A 5-year-old boy was presented with the chief complaint of gradually blurred vision since 1 year ago. Visual acuity were 0.1 and closed face finger counting in the right and left eyes, respectively. An ophthalmology examination revealed lens opacities with partially reabsorbed lens material and protrusion of the lens surface posteriorly in both eyes (figure 1). The patient was diagnosed with developmental cataracts of the membranous type and posterior lentiglobus in both eyes. The patient underwent a surgical intervention for cataract extraction with aspiration technique. A spontaneous posterior capsule rupture was found with a shape like a lentiglobus. An anterior vitrectomy was performed. An intraocular lens was implanted. At one month after surgery, the best corrected visual acuities were 0.5 in both eyes (figure 2). Discussion : Several difficulties can be encountered during pediatric cataract surgery with the posterior lentiglobus morphology because of the thin or ruptured capsule. Previous studies have found preoperative and intraoperative posterior capsule rupture in 25% and 3.13% of lentiglobus cases, respectively. Hydrodissection should be avoided due to the weakness of the posterior capsule. ConclusionAppropriate surgical techniques to anticipate posterior capsule defects in the lentiglobus are required to produce a favorable outcome.
Co-Authors Axa, Alya Putri Caesarya, Sesy Feti Karfiati Memed Irawati Irfani Kuntorini, Maya Sari Wahyu Kuntorini, Mayasari Wahyu Putri, Aliya Numasari Rachmawati, Dinta Raden Roro, Annisa Wahyuni Ratnasari Santosa, Rizki Adi Syifa Rahmani, Syifa