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All Journal Jurnal Impresi Indonesia Journal of Health Science and Medical Therapy
Laksmi, Ni Putu Citra
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Religion Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Relationship between Husband's Social Support and Participation in Pregnant Women Class in Denpasar City in 2019 Laksmi, Ni Putu Citra
Journal of Health Science and Medical Therapy Том 2 № 01 (2024): Journal of Health Science and Medical Therapy
Publisher : PT. Riset Press International

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59653/jhsmt.v2i01.444

Abstract

The Pregnant Women class program is one of the government programs to increase the knowledge of pregnant women about pregnancy, preparation for childbirth, postpartum, newborns, and toddler development so that mothers are expected to be able to identify health problems experienced, but maternal participation in the class of pregnant women is low. The husband's social support is a strengthening factor for mothers to be able to participate in classes for pregnant women. This study aims to see whether there is a relationship between a husband's social support and participation in classes for pregnant women. This study is an observational analytical study with a cross-sectional approach. The sampling technique is non-probability sampling by consecutive sampling of 78 people. This research was conducted from April 1 to May 1, 2019, at the Denpasar City Health Center. The results showed that most of the husband's social support was weak (56%) and mothers did not participate in classes for pregnant women (56%). Statistical tests with the correlation of contingency coefficients obtained ρ = 0.000 value and r value = 0.707, meaning that there is a strong relationship between the husband's social support and participation in pregnant women's classes. The implication of this study is to increase knowledge related to husbands' social support factors that play a role in women's participation in pregnant women's classes.
The Effect of Soybean Ethanol Extract in Tnf-? Levels of Huvecs Culture Induced by Preeclampsia Plasma Mestika, Luh Citrarasmi Dara; Aslina, Wiwit Indriyani; Dyantari, Putu Eva Yuni; Laksmi, Ni Putu Citra; Sumiati, Sumiati
Jurnal Impresi Indonesia Vol. 5 No. 2 (2026): Jurnal Impresi Indonesia
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v5i2.7565

Abstract

The main characteristics of preeclampsia are endothelial dysfunction and inflammatory response of the immune system. Oxidative stress contributes to the pathogenesis of preeclampsia by increasing tumor necrosis factor-? (TNF-?) due to increased reactive oxygen species (ROS). Isoflavones are known to be able to prevent endothelial dysfunction due to increased ROS and proinflammatory cytokines. This study aims to determine the effect of soybean extract on TNF-? associated with preeclampsia using the endothelial cell culture method. The study using in vitro design with human umbilical vein endothelial cells (HUVECs) cultures sample induced by normotensive plasma and preeclampsia plasma and then given various doses of soybean ethanol extract. The TNF-? level of each observation group was determined by the enzyme-linked immunosorbent assay (ELISA) procedure. Statistical analysis were performed with One-Way ANOVA test using SPSS Version 25. Statistical analysis showed a significant difference (p < 0.05) in TNF-? levels of HUVECs cultures exposed to preeclampsia plasma. Compared to the group exposed only to preeclampsia plasma (223.975±5.222ng/mL), the model given a dose of 35 ppm soybean ethanol extract showed a significant decrease in TNF-? levels (178.350±10.093ng/mL), similar to the control group exposed to normal plasma (185.993±16.393ng/mL). This study results indicate that the bioactive compounds in soybean ethanol extract assumed can reduce TNF-? levels in HUVECs cultures induced by preeclampsia plasma and have a potential future therapy for preeclampsia.
Co-Authors Aslina, Wiwit Indriyani Dyantari, Putu Eva Yuni Mestika, Luh Citrarasmi Dara Sumiati Sumiati