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All Journal Indonesian Journal of Pharmaceutical Science and Technology FITOFARMAKA: Jurnal Ilmiah Farmasi
Yulianita, Yulianita
Indonesian Journal of Pharmaceutical Science and Technology
Chemistry Computer Science & IT Medicine & Pharmacology

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Formulation of Instant Granule Containing Nano Calcium from the Shell of Freshwater Mussels (Anodonta woodiana) for Autism Children Aminingsih, Tri; Srie Rahayu, Sata Yoshida; Yulianita, Yulianita
Indonesian Journal of Pharmaceutical Science and Technology Suppl 1, No. 1 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (387.738 KB) | DOI: 10.15416/ijpst.v1i1.16125

Abstract

The small particle size of nano calcium from freshwater mussels shell will tend to increase the absorp- tion of calcium by human’s body and will be very well consumed by children with special needs to suppress hyperactivity disorders that caused by mercury. This study aimed to create and determine the best instant granule formulation containing nano calcium from freshwater mussels shell. The research method began with the manufacture of freshwater mussels shell powder and isolated nano calcium. Nano calcium was tested for its solubility in acid. The granule formula was made with stevia varia- tions. Instant granule evaluation included granule ow test, rest angle, compressibility, water content, solubility, hedonic test, and calcium bioavailability. The results showed that nano calcium was soluble in 1:1 ratio of citric and tartrate acids, so that each formula needs 1.2% citric and 1.2% tartrate acids. Based on the avor, aroma, and texture, the most preferred granule formula contained 600 mg nano calcium, 60 mg citric acid, 60 mg tartaric acid, 400 mg stevia each sachet weighing 5 g. The best in- stant granule evaluation showed that the ow rate was 4.253 g/sec, 33.90 rest angle, 4.65% compress- ibility, 2.21% water content, soluble time 58 second and calcium bioavailability was 100%. Key words: Calcium bioavailability, detoxi cation, freshwater mussels, instant granule, nano cal- cium.
FORMULASI TABLET HISAP KOMBINASI EKSTRAK TEH HIJAU, PEGAGAN DAN JAHE MERAH DENGAN VARIASI KONSENTRASI NA-SIKLAMAT Yulianita, Yulianita
FITOFARMAKA | Jurnal Ilmiah Farmasi Vol 4, No 2 (2014): FITOFARMAKA
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (66.108 KB)

Abstract

Teh hijau, pegagan dan jahe merah merupakan beberapa tanaman yang memilikikhasiat baik untuk kesehatan dan salahsatu khasiatnya adalah sebagai peningkat stamina. Sehingga dilakukan penelitian formulasi kombinasi ketiga tanaman tersebut sebagai tablet hisap. Telah dilakukan formulasi tablet hisap yang mengandung bahan aktif ekstrak teh hijau, jahe merah dan pegagan dengan perbedaan kadar pemanis Na siklamat
Co-Authors SATA YOSHIDA SRIE RAHAYU Tri Aminingsih