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Artikel Riview: Profil Studi Fitokimia Dan Aktivitas Farmakologi Buah Mangga (Mangifera Indica L.) Kurrota Ayyun; Rosydah, Yeka Khafidz Ila; Atikah, Nandiyyah; Arianti, Shabrina Putri; Maulidini, Cici; Agustino, Faizal; Putri, Nadiya Kamiliya; Seran, Agustinus Alfred; S.Klau, Ivan Charles; Ningsih, Arista Wahyu
Jurnal Sains Farmasi Dan Kesehatan Vol. 1 No. 2 (2023): September - Desember
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v1i2.346

Abstract

The mango plant (Mangifera indica L.) is a plant that is often found around. Empirically, this plant has been widely used in traditional medicine around the world, one of which is ayuverda treatment from India. Due to these many empirical functions, many studies have been conducted on the pharmacological activities of mango plants. This article discusses the pharmacological activities and phytochemical tests that have been investigated and confirmed both in vitro and in vivo with the literature review method. The results obtained show the presence of several compounds found in mango plants such as: alkaloids, flavonoids, terpenoids, saponins, tannins, phenols and steroids. Because of the compounds contained in mango plants, there are several pharmacological activities including: antioxidant activity, antidiabetic, anti-inflammatory, hepatoprotective, anti-hyperlipidemia, anti-hyperglycemia, antimicrobial, antiobesity, antifungal, antidiarrheal, and antitumor, among others.
Antimicrobial activity and phytochemicals compound profile of ethanol extract Moringa leaf (Moringa oleifera) compounds by FTIR Ningsih, Arista Wahyu; Safıra, Aulia Dinda; Giovano, Andre; S.Klau, Ivan Charles
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 1 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i1.1231

Abstract

Moringa plants are known in various parts of the world as a type of vegetable plant that is rich in nutrients and has multiple properties, one of which is as an antimicrobial. This research was conducted to test the antimicrobial inhibition of Moringa leaf decoction and ethanol extract against the growth of Escherichia coli and Aspergillus niger. The antimicrobial test in this study used the Disc diffusion method using various concentrations, including 25%, 50%, 75%, and 100%. There were two test samples, Moringa leaf decoction and ethanol extract using the maceration method with 96% ethanol solvent. In addition to the test group, there was also a control group, namely a positive control using chloramphenicol and ketoconazole antibiotics, negative control using aquadest as a decoction solvent, and DMSO as an extraction solvent. The ethanol extract was identified by the FTIR method. The results showed that Moringa leaf decoction and Moringa leaf ethanol extract could be used as antibacterial. Inhibition zones on Escherichia coli bacteria produced at concentrations of 25%, 50%, and 75% had a weak zone of inhibition category for both decoction and ethanol extract of Moringa leaves. Meanwhile, at a concentration of 100%, the decoction has a weak zone of inhibition and 100% ethanol extract of Moringa leaves can inhibit 8.25 mm which is included in the medium category. The inhibition zones of the fungus Aspergillus niger produced at concentrations of 25%, 50%, 75%, and 100% had no inhibition on both the decoction and ethanol extract of Moringa leaves. From the analysis of functional groups using the FTIR method, it can be predicted that in the Moringa leaf extract with methanol as solvent there are groups of phenolic compounds or flavonoids.
ARTIKEL REVIEW : STUDI FITOKIMIA DAN FARMAKOLOGI PISANG KEPOK (Musa paradisiaca) Khoiriyah, Siti; Triani, Rheina Febby; Putra, Achmad Ikrar Toriq Purnomo; Andini, Viola Putri; Dewi, Wulan Novita; Salim, Nadiya Difilla; Ocatviani, Siti Yunita; S.Klau, Ivan Charles; Ningsih, Arista Wahyu
BENCOOLEN JOURNAL OF PHARMACY Vol. 5 No. 1 (2025): April
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v5i1.38978

Abstract

Penelitian ini bertujuan untuk mengkaji senyawa fitokimia yang terkandung dalam pisang kepok (Musa paradisiaca) serta mengevaluasi potensi farmakologinya. Pisang kepok dikenal sebagai salah satu varietas pisang yang memiliki manfaat kesehatan, namun kajian mendalam terkait komponen fitokimia dan aktivitas biologisnya masih terbatas. Dalam studi ini, ekstrak pisang kepok dianalisis menggunakan berbagai metode fitokimia, seperti uji kandungan flavonoid, tanin, alkaloid, saponin, dan fenolik. Selain itu, dilakukan pengujian aktivitas farmakologi ekstrak terhadap aktivitas antioksidan dan anti-inflamasi dengan pendekatan in vitro. Hasil penelitian menunjukkan bahwa pisang kepok mengandung senyawa fitokimia yang signifikan dan memiliki potensi sebagai sumber antioksidan alami serta agen anti-inflamasi. Penemuan ini memberikan wawasan baru mengenai penggunaan pisang kepok dalam pengembangan obat herbal atau suplemen kesehatan.