Mazidah Noer Inayah
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Potensi Bakteri Tanah Penghasil Senyawa Antimikrob Untuk Menghambat Pertumbuhan Bakteri Escherichia Coli dan Staphylococcus Aureus Mazidah Noer Inayah; Suci Indah Budiarti
Jurnal Nurse Vol. 4 No. 1 (2021): Januari : Jurnal Nurse
Publisher : STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/nurse.v4i1.234

Abstract

Antimicrobials are molecules that inhibit the growth of microbes. Some bacterial species, consisting of actinomycetes and fungi, are capable of producing antimicrobial substances. Streptomyces, commonly referred to as soil bacteria, are a group of actinomycetes that produce multiple antimicrobial agents. Other soil bacteria that may produce antibiotics include Pseudomonas, Bacillus, Nocardia, Kibdelosporangium, and Roseobacter. Thereby, soil is one of the potential sources that is capable of being used as a research sample for discovering and collecting antibiotic-producing bacteria, especially new types of antibiotics that weren't previously discovered. The latest research about antimicrobials (antibiotics) has been driven by the high number of cases of bacterial resistance. The study aims to investigate the potential of antimicrobial-producing bacteria from the soil to inhibit the pathogenic bacteria Staphylococcus aureus and Escherichia coli. The research procedure involves soil sampling, isolating the antimicrob-producing bacteria, describing the morphology of the bacterial colony and bacterial cells, purifying and regenerating the bacterial culture, and testing the activity of antimicrobial substances against E. coli and S. aureus. The study revealed four bacterial isolates: E1, E2, S1, and S2, that could possibly suppress the growth of S. aureus and E. coli. However, the antimicrobial activity of the four bacteria remained considerably smaller compared with 100 mg of chloramphenicol.
Gambaran Hasil Pemeriksaan Sifilis pada Ibu Hamil di Rumah Sakit Wijayakusuma Purwokerto Oksita Asri Widyayanti; Mazidah Noer Inayah; Esa Dhiandani; Nunuk Herowati
Jurnal Medika Nusantara Vol. 1 No. 1 (2023): Februari : Jurnal Medika Nusantara
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/medika.v1i1.1332

Abstract

Syphilis is a sexually transmitted disease caused by the bacteria Treponema pallidum. Syphilis is a resilient and systemic disease. Syphilis is passed on sexually by vaginal, anogenital, and orogenital contact. Non-sexual interactions, such as physical contact and blood transfusions, also remain possible. The disease can also spread vertically from mother to fetus (transplacental), resulting in congenital syphilis in the fetus. According to the Ministry of Health of the Republic Indonesia, there were 7055 new cases of syphilis in Indonesia during 2018. According to the latest data, 6% of pregnant mothers in Pekalongan possessed syphilis. Other studies found that 13% of pregnant mothers in Northern Halmahera were infected with T. pallidum or proved positive for syphilis. The number of cases of pregnant mothers suffering from syphilis encouraged the conduct of this study to figure out the features of pregnant mothers suffering from syphilis recognized at Wijayakusuma Hospital, Purwokerto, Banyumas. In this study, pregnant mothers were examined using the rapid test for syphilis. The findings revealed that 20 pregnant mothers were negative for T. pallidum or syphilis.