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Journal : Thrive Health Science Journal

Global Perspectives on Drug Regulatory Bodies: Roles, Challenges, and Collaborative Frameworks Ahmed, Rashed
THRIVE Health Science Journal Vol. 2 No. 2 (2025): September
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i2.322

Abstract

The article "Comparison of Drug Regulatory Bodies: EMA, DGDA, ISO, WHO, TGA, MHRA, and FDA" presents a comprehensive analysis of global drug regulatory organizations, focusing on their roles, responsibilities, and impact on public health. The research delves into the historical development, operational frameworks, and collaborative efforts of these agencies to ensure the safety, efficacy, and quality of pharmaceutical products and medical devices. By incorporating methodologies such as literature review, comparative analysis, critical evaluation, and historical contextualization, the study identifies key similarities and differences among these organizations. The article also examines the critical role of pharmacists in these regulatory bodies, emphasizing their involvement in drug evaluation, pharmacovigilance, and policy development. Furthermore, the study explores the concepts of In-Process Quality Assurance (IPQA) and In-Process Quality Control (IPQC), illustrating their necessity even in the presence of established Quality Control (QC) and Quality Assurance (QA) departments. By addressing challenges such as long approval times, high compliance costs, regulatory inconsistencies, and limited resources in developing countries, the research underscores the importance of global collaboration and regional adaptation in drug regulation. The article concludes by advocating for strengthened regulatory systems, enhanced international cooperation, and balanced approaches to ensure the rational use of drugs and equitable access to quality medicines worldwide.
Understanding Down Syndrome: Global Perspectives, Advances, and Challenges in the Context of Bangladesh Ahmed, Rashed; Tamim, Md. Tanzimur Rahman
THRIVE Health Science Journal Vol. 2 No. 1 (2025): March
Publisher : Balai Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56566/thrive.v2i1.316

Abstract

Down syndrome (DS), or Trisomy 21, is a genetic disorder characterized by intellectual disabilities, developmental delays, and various health complications. This comprehensive review examines the causes, symptoms, and management strategies of DS, emphasizing global research advancements and their relevance to Bangladesh. This article highlights emerging therapies, genetic studies, and social advocacy efforts, proposing strategies to bridge the gap in healthcare and research. It aims to inspire collaborative efforts to improve the quality of life for individuals with DS globally and within Bangladesh. Down Syndrome (DS), or Trisomy 21, is a genetic disorder characterized by developmental delays, intellectual disabilities, and a variety of health complications. This review explores the causes, symptoms, and management strategies of DS, emphasizing the latest global advancements such as CRISPR gene editing and neurodevelopmental imaging. Despite these breakthroughs, Bangladesh continues to face significant challenges in diagnosing and managing DS due to inadequate healthcare infrastructure, limited diagnostic resources, and persistent societal stigma.The paper highlights disparities in outcomes for individuals with DS between developed and developing nations, focusing on the stark differences in healthcare access, early intervention programs, and societal acceptance. Case studies illustrate the successes of advanced therapies in developed countries while underscoring the gaps in resources and awareness in Bangladesh. These findings emphasize the urgent need for targeted interventions, including improved diagnostic tools, enhanced healthcare systems, and inclusive social practices in developing nations.Additionally, the article examines the role of emerging therapies and advocacy efforts in bridging these gaps. By leveraging global advancements, promoting public-private partnerships, and fostering international collaborations, the study proposes actionable strategies to improve the quality of life for individuals with DS.