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All Journal Jurnal Insan Farmasi Indonesia
Nur Aisiyah, Astri Dewi
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics

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FORMULASI OBAT KUMUR EKSTRAK DAUN BINAHONG DAN KAYU MANIS TERHADAP BAKTERI Streptococcus mutans Rakhmayanti, Regia Desty; Nur Aisiyah, Astri Dewi
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1781

Abstract

Dental caries is a disease in the oral cavity, this disease can be prevented by using mouthwash. Plants that have antibacterial activities include binahong leaves  and cinnamon . This study aims was to determine the quality and antibacterial activity of mouthwash that containing against Streptococcus mutans. Mouthwash preparations was carried out by various concentrations of binahong leaves and cinnamon extract. Preparation F0 is without extract, F1 (6%:3%), F2 (7%:3%), F3 (8%:3%). The organoleptic test results of the mouthwash was clear brown in color and had a distinctive aroma of binahong leaves and cinnamon. The pH test results were F0 6.529±0.16; F1 5.256±0.004; F2 5.333±0.002; and F3 5.373±0.003. The density measurements results were F0 1.0766±0.04852; F1 1.0309±0.00056; F2 1.0317±0.00032; and F3 1.0364±0.00325. The viscosity measurement results were F0 3.170±0.02; F1 3.203±0.02; F2 3.323±0.01; and F3 3.380±0.02. The antibacterial activity test result were F0 0.00 mm; F1 6.39±0.03 mm; F2 7.29±0.06 mm; F3 8.89±0.07 mm; negative control (distilled water) 0.00 mm; and positive control (chlorhexidine 0.2%) 21.35±0.10 mm. The preparation fulfilled the physical quality parameter requirements of mouthwash and has antibacterial activity against Streptococcus mutans.
Co-Authors Rakhmayanti, Regia Desty