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All Journal IKRA-ITH Teknologi Jurnal Sains dan Teknologi Jurnal Insan Farmasi Indonesia Pharmademica: Jurnal Kefarmasian dan Gizi Journal of Local Therapy
Rakhmayanti, Regia Desty
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Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Physics Public Health

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FORMULASI HARD CANDY EKSTRAK KAYU SECANG (Caesalpinia sappan L.) Rakhmayanti, Regia Desty; Hastuti, Rini Tri
IKRA-ITH TEKNOLOGI : Jurnal Sains & Teknologi Vol 3 No 3 (2019): IKRAITH-TEKNOLOGI VOL 3 No 3 Bulan November 2019
Publisher : Fakultas Teknik Universitas Persada Indonesia YAI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (777.953 KB)

Abstract

Tanaman secang banyak terdapat di Indonesia dimana memiliki daya simpan dalam jangkapanjang. Salah satu usaha pemanfaatan kayu secang yaitu dengan mengolahnya menjadi permenkeras. Pengolahan kayu secang menjadi permen keras juga merupakan suatu inovasi. Penelitianini bertujuan untuk mengetahui hasil uji fisik permen keras ekstrak kayu secang. Penelitianmenggunakan metode percobaan dalam rancangan deskriptif kuantitatif dengan perlakuanpenambahan jumlah ekstrak FI (8,3%), FII (11,1%), FIII (16,6%). Pengamatan dilakukan terhadapmutu permen keras ekstrak kayu secang sesuai persyaratan mutu permen keras SNI 3547.1:2008,yang meliputi uji organoleptik, kadar air, kadar abu dan nilai pH. Hasil penelitian menunjukkanketiga formula memiliki pH FI (5,6), FII (5,3) dan FIII (5). Hasil kadar air ketiga formula yaitu FI(0,5%), FII (2%), dan FIII (1%). Hasil kadar abu ketiga formula yaitu FI (1,6%), FII (2,2%) andFIII (1,5%). Hasil organoleptik tekstur keras dan warna orange. Hard candy dengan penambahanekstrak kayu secang memenuhi syarat mutu SNI 3547.1:2008 untuk parameter tekstur, rasa, bau,kadar air, dan kadar abu. Sedangkan nilai pH memenuhi persyaratan pH menurut Lees dan Jackson(1999).
FORMULASI OBAT KUMUR EKSTRAK DAUN BINAHONG DAN KAYU MANIS TERHADAP BAKTERI Streptococcus mutans Rakhmayanti, Regia Desty; Nur Aisiyah, Astri Dewi
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1781

Abstract

Dental caries is a disease in the oral cavity, this disease can be prevented by using mouthwash. Plants that have antibacterial activities include binahong leaves  and cinnamon . This study aims was to determine the quality and antibacterial activity of mouthwash that containing against Streptococcus mutans. Mouthwash preparations was carried out by various concentrations of binahong leaves and cinnamon extract. Preparation F0 is without extract, F1 (6%:3%), F2 (7%:3%), F3 (8%:3%). The organoleptic test results of the mouthwash was clear brown in color and had a distinctive aroma of binahong leaves and cinnamon. The pH test results were F0 6.529±0.16; F1 5.256±0.004; F2 5.333±0.002; and F3 5.373±0.003. The density measurements results were F0 1.0766±0.04852; F1 1.0309±0.00056; F2 1.0317±0.00032; and F3 1.0364±0.00325. The viscosity measurement results were F0 3.170±0.02; F1 3.203±0.02; F2 3.323±0.01; and F3 3.380±0.02. The antibacterial activity test result were F0 0.00 mm; F1 6.39±0.03 mm; F2 7.29±0.06 mm; F3 8.89±0.07 mm; negative control (distilled water) 0.00 mm; and positive control (chlorhexidine 0.2%) 21.35±0.10 mm. The preparation fulfilled the physical quality parameter requirements of mouthwash and has antibacterial activity against Streptococcus mutans.
FORMULATION AND TESTING OF ANTIBACTERIAL ACTIVITY OF FACIAL TONER PREPARATIONS CHINESE BELT LEAF EXTRACT (Peperomia pellucida L. Kunth) AGAINST THE BACTERIA Propionibacterium acnes Nasikin, M. Ali; Ridlo, Achmad; Rakhmayanti, Regia Desty; Hapsari, Azizah Nur
Journal of Local Therapy Vol 3 No 2 (2024): Journal of Local Therapy
Publisher : Pusat Unggulan IPTEK Poltekkes Kemenkes Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31290/jlt.v3i2.4674

Abstract

Abstract: Chinese betel leaf (Peperomia pellucida L.Kunth) is a herbal plant that can be used to treat abscesses, acne, boils and skin inflammation. Chinese betel leaves contain chemical compounds including alkaloids, flavonoids, saponins, tannins and triterpenoids which can inhibit the growth of Propionibacterium acnes bacteria. The Chinese betel leaf extract content can be used as a refreshing toner, especially for dry and acne-prone skin. The aim of this research is to determine the results of physical quality tests and antibacterial activity of Chinese betel leaf extract facial toner formulations with an additional active ingredient concentration of 7.5%; 15% and 30%. This type of research is experimental research with a descriptive research design. The organoleptic test results of the base are clear and odorless, while the other 3 formulas are brownish green in color, have a distinctive aroma of Chinese betel leaf extract and are in liquid form. The homogeneity test results of the preparation are homogeneous. F0 pH test results 6.327; FI 5.344; FII 5,243 and FIII 5,067. Viscosity test results F0 5.32 cps FI 6.34 cps and FII 6.33 cps. The results of the antibacterial activity test F0, FI, FII, and FIII were respectively 0.00 mm, there was no inhibition zone, 7.37 mm, 13.35 mm, 16.24 mm and in the positive control clindamycin it was 21.17 mm. Based on the results of the physical quality test and antibacterial activity of the toner preparation, the toner preparation has met existing quality standards so it is safe to use and the toner preparation with the strongest antibacterial activity is found in FIII.
Analisa Kandungan Formaldehid Pada Sediaan Cat Kuku (Kutek) yang Diperjualbelikan di Pasar Kota Wonogiri Andriastuti, Deitra Aprilia; Nasikin, M. Ali; Rakhmayanti, Regia Desty
PHARMADEMICA : Jurnal Kefarmasian dan Gizi Vol 4 No 1 (2024): April - September
Publisher : LPPM-KI - POLTEKKES PIM (Formerly AKAFARMA-AKFAR PIM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54445/pharmademica.v4i1.61

Abstract

Nail polish is a pigment that is deposited in a volatile solvent to cover the natural color of the nail and as an attractiveness enhancer that uses formaldehyde. Formaldehyde (H2CO) with the trade name formalin solution, which functions as a nail polish hardener, so that the nail polish is more adhesive and thicker. This study aims to determine whether nail polish preparations traded in the Wonogiri city market contain formaldehyde with levels that exceed the limit according to the Regulation of the Head of the Food and Drug Supervisory Agency of the Republic of Indonesia Number 18 of 2015, which is <5%. Qualitative analysis used resorcinol reagent, while quantitative analysis used UV-Vis spectrophotometry at a wavelength of 550 nm. The sample used in this study was nail polish taken from the market in Wonogiri, 9 samples with sample codes A, B, C, D, E, F, G, H, and I. The results showed that 9 samples of nail polish studied meet the requirements of the level limit of less than 5%, with the largest level obtained at 3.349% for the code I sample and the smallest level at 0.750% for the code E sample. Keywords: nail polish, formaldehyde, UV-Vis spectrophotometry  
Analisis Kandungan Hidrokuinon pada Hand Body Lotion yang Dijual di Kecamatan Klaten Tengah dengan Metode Spektrofotometri Uv Vis Ningrum, Ayu Dwi Retno; Rakhmayanti, Regia Desty; Nasikin, M. Ali
PHARMADEMICA : Jurnal Kefarmasian dan Gizi Vol 4 No 2 (2025): Oktober - Maret
Publisher : LPPM-KI - POLTEKKES PIM (Formerly AKAFARMA-AKFAR PIM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54445/pharmademica.v4i2.66

Abstract

Hydroquinone is a compound used as a whitening agent and to prevent pigmentation. The use of hydroquinone in hand body lotion is prohibited by BPOM because it can cause skin irritation, redness, burning sensation, bluish or blackish skin (ochronosis), cancer. This study aims to identify the content and determine the levels of hydroquinone in hand body lotion sold in Klaten Tengah District using the UV-Vis spectrophotometry method. The research method used is quantitative descriptive. The samples obtained were eight and were coded A, B, C, D, E, F, G, and H. The results showed that all samples were positive for hydroquinone with levels of 2.54%; 0.20%; 0.14%; 0.17%; 0.30%; 1.25%; 0.37%; and 2.10% so that they do not meet the requirements of BPOM RI No.23 of 2019.  
Co-Authors Achmad Ridlo Andriastuti, Deitra Aprilia Hapsari, Azizah Nur Nasikin, M. Ali Ningrum, Ayu Dwi Retno Nur Aisiyah, Astri Dewi Rini Tri Hastuti