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The Potential of Andrographis paniculata as a Supplement for the Management of Benign Prostate Hypertrophy (BPH): A Systematic Literature Review Amal, Rizki Jaya; Irfansyah
Eureka Herba Indonesia Vol. 4 No. 2 (2023): Eureka Herba Indonesia
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ehi.v4i2.70

Abstract

Andrographis paniculata has been studied for their potential protective action on benign prostate hypertrophy (BPH). This polyphenol has been reported to repair the antioxidant defense mechanisms in the prostate, reduce inflammation, and inhibit IGF-I and IGF-II. Andrographis paniculata has been studied for its potential protective action on benign prostate hypertrophy (BPH) and its ability to reduce inflammation in the prostate. This study aimed to explore various scientific evidence related to the exploration of the potential of Andrographis paniculata in the management of benign prostate hypertrophy (BPH). These three studies consistently present data demonstrating the superiority of andrographolide isolate in the apoptosis initiation of prostate cells. Increased apoptosis of prostate cells is believed to cause a decrease in the mass of prostate tissues and organs. The decrease in prostate mass will relieve pressure on the urethral canal and will eliminate complaints of difficulty urinating in patients with BPH. In conclusion, Andrographis paniculata has the potential to supplementation in the management of benign prostate hypertrophy through regulation of prostate cell apoptosis initiation.
Analysis of Risk Prediction Models to Identify Patients at High Risk of Urinary Incontinence Amal, Rizki Jaya; Suherdy; Delfi Sanutra; Munawmarah; Jevo Rifan Sandikta
Sriwijaya Journal of Internal Medicine Vol. 2 No. 2 (2024): Sriwijaya Journal of Internal Medicine
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjim.v2i1.110

Abstract

Introduction: Urinary incontinence (UI) is a common health problem and is often undiagnosed in hospital patients. UI can cause complications such as urinary tract infections, dermatitis, and decreased quality of life. This study aims to apply a risk prediction model to identify patients at high risk of experiencing UI at Tengku Peukan General Hospital, Southwest Aceh, Indonesia. Methods: This study used a prospective cohort design. Data was collected from 100 patients hospitalized at Tengku Peukan General Hospital, Southwest Aceh. A risk prediction model was developed using logistic regression. Model performance is measured by AUC-ROC values and accuracy. Results: The risk prediction model developed had an AUC-ROC value of 0.85 (95% CI: 0.78-0.92) and an accuracy of 82%. The most significant risk factors for UI are age, gender, history of UI, and use of diuretic medications. Conclusion: This risk prediction model can help nurses and doctors identify patients who are at high risk of experiencing UI at Tengku Peukan General Hospital, Southwest Aceh. Early intervention in high-risk patients can help prevent UI complications and improve the patient's quality of life.
INTRAVESICAL FOREIGN BODIES MIMICKING BLADDER CALCULI: A CASE REPORT Amal, Rizki Jaya; Irfansyah; Putra, Aulia Rahman; Alvieda Nainggolan, Irbah Rea
Indonesian Journal of Urology Vol 32 No 1 (2025)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v32i1.923

Abstract

Objective: In this case report, we will present a patient with an intravesical foreign body mimics bladder calculi. Case(s) presentation: A 37-year-old man presented with pain in the suprapubic area. The patient had a history of several urological procedures. First, at the age of 11 years, He had an augmentation cystoplasty due to a congenital neurogenic bladder. Later, at the age of 15 and 20, He experienced two traumatic bladder ruptures requiring open repair, and the Mitrofanoff appendicovesicostomy for intermittent self-catheterization was performed. Discussion: The patient underwent an emergency cystoscopy that revealed calcified cut ends of four urethral catheter tips. Cystolitholapaxy was performed to crush these calcified foreign bodies facilitating cystoscopic removal. Conclusion: A 37-year-old man presented with intermittent suprapubic pain caused by intravesical foreign bodies. Hence, Cystolitholapaxy was performed to remove these calcified foreign bodies. The patient was observed and discharged from the hospital after seven days of treatment. Keywords: Bladder, foreign bodies, suprapubic pain, vesica urinaria.
Analysis of Studies on the Role of Hormones in Micropenis Disorders: A Systematic Literature Review Amal, Rizki Jaya; Irfansyah; Muhammad Arif Hasan; Aulia Putra Rahman
Open Access Indonesian Journal of Medical Reviews Vol. 3 No. 6 (2023): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v3i6.420

Abstract

A deep understanding of the role of specific hormones in genital development is key to designing effective therapeutic approaches. Factors such as testosterone deficiency, growth hormone disorders, or other hormonal imbalances can be targets for hormonal interventions that can affect penis size. This study aimed to explore the role of hormonal aspects in micropenis disorders. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the role of hormonal aspects in micropenis disorders. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Aspects of the hormonal role in micropenis include several key elements that influence the development of genital organs in men. Hormones, such as testosterone, growth hormone, estrogen, and dihydrotestosterone (DHT), play an important role in stimulating penis growth and development. Proper hormonal balance is necessary for normal genital development, and disturbances in the production of or response to these hormones may contribute to conditions such as micropenis.