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All Journal JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Maulana, Mochamad Luqni
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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UJI AKTIVITAS TABIR SURYA EKSTRAK DAN LOTION KUNYIT (Curcuma domestica Val.) SECARA INVITRO MENGGUNAKAN SPEKTROFOTOMETER UV-VIS Alfian, Muhammad; Hasanudin, Muhammad Nurul; Maulana, Mochamad Luqni; Mustainin, Muhammad
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 1 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i1.1623

Abstract

Excessive UV B radiation can lead to premature skin aging, but research suggests that turmeric (Curcuma domestica Val.) may have antioxidant compounds that could serve as a sunscreen. To investigate, the researchers tested turmeric extracts and lotions in vitro using a UV-Vis spectrophotometer. They extracted turmeric by maceration with 70% ethanol to obtain a thick extract, then evaluated the physical characteristics of turmeric lotion preparations including organoleptics, spreadability, adhesion, pH, SPF values (using the Mansur method), and Erythema Transmission Percentage (%T) in vitro using a UV-Vis spectrophotometer with absorbance wavelengths of 290-320 nm. The results showed that F1 to F5 turmeric lotion preparations were semi-solid, brownish yellow, fragrant, with spreadability above 7 cm, adhesion less than 1 second, and pH below 8. The highest SPF value of turmeric extract was at a concentration of 500 mg with SPF 46, while the highest SPF of turmeric lotion was F5 with SPF 15. All turmeric extracts are categorized as sunblock, while F5 lotion is also sunblock and F1 to F4 lotions are fast-tanning. Although the SPF value decreases when turmeric extract is made into a lotion, it still has sunscreen potential.
UJI AKTIVITAS TABIR SURYA EKSTRAK DAN LOTION KUNYIT (Curcuma domestica Val.) SECARA INVITRO MENGGUNAKAN SPEKTROFOTOMETER UV-VIS Alfian, Muhammad; Hasanudin, Muhammad Nurul; Maulana, Mochamad Luqni; Mustainin, Muhammad
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 1 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i1.1623

Abstract

Excessive UV B radiation can lead to premature skin aging, but research suggests that turmeric (Curcuma domestica Val.) may have antioxidant compounds that could serve as a sunscreen. To investigate, the researchers tested turmeric extracts and lotions in vitro using a UV-Vis spectrophotometer. They extracted turmeric by maceration with 70% ethanol to obtain a thick extract, then evaluated the physical characteristics of turmeric lotion preparations including organoleptics, spreadability, adhesion, pH, SPF values (using the Mansur method), and Erythema Transmission Percentage (%T) in vitro using a UV-Vis spectrophotometer with absorbance wavelengths of 290-320 nm. The results showed that F1 to F5 turmeric lotion preparations were semi-solid, brownish yellow, fragrant, with spreadability above 7 cm, adhesion less than 1 second, and pH below 8. The highest SPF value of turmeric extract was at a concentration of 500 mg with SPF 46, while the highest SPF of turmeric lotion was F5 with SPF 15. All turmeric extracts are categorized as sunblock, while F5 lotion is also sunblock and F1 to F4 lotions are fast-tanning. Although the SPF value decreases when turmeric extract is made into a lotion, it still has sunscreen potential.
Testing the effectiveness of hair growth tonic with cocoa bean extract on mice for physical stability and activity Alfian, Muhammad; Hasanudin, Muhammad Nurul; Maulana, Mochamad Luqni
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.270-279.2023

Abstract

Cocoa is a highly valued plant due to its versatile uses, including being processed into cosmetic products. Hair loss and slow hair growth are common hair-related concerns that can be effectively addressed through the use of hair tonics. Previously, research has shown that cocoa bean can effectively stimulate hair growth when made into a cream. Our research aimed to determine the secondary metabolite content of cocoa beans extract, formulate the extract into a hair growth tonic, and test its physical stability and effectiveness on hair growth in mice. Cocoa beans extracted by maceration method and conducted phytochemical screening. This extract was then used to create three formulations with different extract concentrations of 0.2%, 0.3%, and 0.5%, which were tested for physical stability, including organoleptic properties, homogeneity, pH, and specific gravity. Mice were divided into five treatment groups, hair length growth measurements were taken every week, on the 7th, 14th and 21st days. Six strands of hair were taken from the application area, and their length was measured using a calliper. Results revealed that cocoa seed extract contains flavonoids, alkaloids, tannins, and phenolics. The formula with a 0.3% concentration of cocoa bean extract showed the best physical stability. Hair growth tests on mice showed no significant difference between the 0.3% and 0.5% cocoa bean extract formulas and the positive control in the second week. The 0.3% formula is the best for ensuring good physical stability and promoting hair growth in mice when used twice daily for two weeks
Co-Authors Hasanudin, Muhammad Nurul Muhammad Alfian Muhammad Alfian, Muhammad