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All Journal Chemistry Indonesian Journal of Chemical Research Indo-MathEdu Intellectuals Journal
Karimah, Aulia
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Biochemistry, Genetics & Molecular Biology Chemistry Engineering Environmental Science Mathematics

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Studi Literatur: Peran Penting Literasi Membaca dalam Upaya Meningkatkan Karakter Positif Siswa Sekolah Dasar Karimah, Aulia; Alfatikarahma, Nasywa; Fauziah, Afif
Indo-MathEdu Intellectuals Journal Vol. 5 No. 1 (2024): Indo-MathEdu Intellectuals Journal
Publisher : Lembaga Intelektual Muda (LIM) Maluku

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54373/imeij.v5i1.670

Abstract

This research aims to analyze the factors that cause low literacy in students. The methodology in this research uses literature study. The data collection technique is carried out by collecting secondary data which includes research results from articles, library sources and other documents relevant to this research. The sources used to collect data were journals obtained from Google Scholar, Garuda, and Sinta. The data analysis technique used is qualitative with stages including reducing data, presenting data, and concluding data. The research results show five student characters that need to be developed through literacy, including religious, nationalist, independent, cooperation and integrity.  Factors that hinder the literacy movement are the lack of reading materials, inadequate teacher resources, and limited facilities in schools. Meanwhile, the factors that support the literacy movement are the motivation of the school principal, the enthusiasm of the teachers, and the availability of libraries.
In Vitro and In Silico Assessment of Methanol Extract from Moringa oleifera Seeds as α-Amylase Inhibitor Natsir, Hasnah; A Arfah, Rugaiyah; Arif, Abdur Rahman; Nadir, Muhammad; Anita, Anita; Sartika, Sartika; Rahmi, Nur; Karimah, Aulia
Indonesian Journal of Chemical Research Vol 12 No 2 (2024): Edition for September 2024
Publisher : Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2024.12-has

Abstract

Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia, posing a global health threat. Current diabetes treatments often rely on synthetic drugs with side effects, prompting the search for safer natural alternatives. This study investigated the secondary metabolic compounds in methanol extract from M. oleifera seeds and evaluated their antidiabetic activity. The α-amylase enzyme was analyzed to determine optimal incubation time, pH, and temperature. The antidiabetic activity was assessed via α-amylase inhibition using in vitro and in silico methods. Phytochemical screening revealed the presence of flavonoids, alkaloids, and tannins in the extract. Optimal enzyme conditions were 30 minutes of incubation, pH 6.9, and 25 °C. The extract showed the highest activity at 15% concentration with 67.94% inhibition and an IC50 of 15.38%, compared to acarbose with 41.76% inhibition and an IC50 of 17.89%. In silico analysis indicated that 9-octadecanoic acid (Z) methyl ester had a lower inhibition constant and binding energy (2.67 mM and -3.51 kcal/mol) than acarbose (15.72 mM and -2.46 kcal/mol), suggesting a higher enzyme affinity. These findings suggest that M. oleifera seeds contain compounds with potential as antidiabetic agents.
Studi Literatur: Peran Penting Literasi Membaca dalam Upaya Meningkatkan Karakter Positif Siswa Sekolah Dasar Karimah, Aulia; Alfatikarahma, Nasywa; Fauziah, Afif
Indo-MathEdu Intellectuals Journal Vol. 5 No. 1 (2024): Indo-MathEdu Intellectuals Journal
Publisher : Lembaga Intelektual Muda (LIM) Maluku

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54373/imeij.v5i1.670

Abstract

This research aims to analyze the factors that cause low literacy in students. The methodology in this research uses literature study. The data collection technique is carried out by collecting secondary data which includes research results from articles, library sources and other documents relevant to this research. The sources used to collect data were journals obtained from Google Scholar, Garuda, and Sinta. The data analysis technique used is qualitative with stages including reducing data, presenting data, and concluding data. The research results show five student characters that need to be developed through literacy, including religious, nationalist, independent, cooperation and integrity.  Factors that hinder the literacy movement are the lack of reading materials, inadequate teacher resources, and limited facilities in schools. Meanwhile, the factors that support the literacy movement are the motivation of the school principal, the enthusiasm of the teachers, and the availability of libraries.
Co-Authors A Arfah, Rugaiyah Abdur Rahman Arif, Abdur Rahman Alfatikarahma, Nasywa Anita Anita Fauziah, Afif Hasnah Natsir Muhammad Nadir Sartika Sartika Solly Aryza