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All Journal Journal of Pharmaceutical Care and Sciences Sains Medisina
Saputri, Nur Arida
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Medicine & Pharmacology

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Review Article : Tanaman Valerianae radix, Myristicae semen, Eleuthroginseng radix, Polygalae radix Untuk Mengatasi Insomnia Nastiti, Kunti; Habibah, Nor; Hidayah, Nurul; Ma'rifah, Nurul; Saputri, Nur Arida
Sains Medisina Vol 2 No 5 (2024): Sains Medisina
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/snsmed.v2i5.410

Abstract

Tidur adalah suatu fenomena fisiologis yang penting dalam menjaga keseimbangan regulasi sistem tubuh. Dibutuhkan waktu sekitar 7-8 jam dalam sehari agar tidur seseorang menjadi efektif. Salah satu gangguan tidur yang sering terjadi adalah insomnia. Penggunaan tanaman obat herbal atau alami banyak digunakan dalam terapi menanganan insomnia. Beberapa tanaman yang memilki khasia untuk mengatasi insomnia, yaitu Valerianae radix, Myristicae semen, Eleuthroginseng radix, dan Polygalae radix. Review article ini dibuat dengan menggunakan metode studi literatur ilmiah. Sumber literatur meliputi jurnal internasional dan nasional, serta laporan penelitian yang dilakukan secara online melalui Google Scholar. Berdasarkan beberapa penelitian, tanaman Valerianae radix, Myristicae semen, Eleuthroginseng radix, dan Polygalae radix memiliki khasiat untuk mengatasi insomnia seperti obat-obatan golongan hipnotik-sedatif.
Uji Aktivitas Antibakteri Ekstrak Kulit Jeruk Kalamansi (Citrofortunella microcarpa bunge) Pada Bakteri Propionibacterium Acnes Saputri, Nur Arida; Darsono, Putri Vidiasari; Mahdiyah, Dede; Audina, Mia
Jurnal Pelayanan Kefarmasian dan Sains Vol 6 No 1 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v6i1.734

Abstract

Background: Acne or acne vulgaris is an inflammatory disease that often occurs in the facial area. Usually characterized by the appearance of small reddish or yellow lumps (because they contain pus). The main organism that causes acne is Propionibacterium acnes. The growth of Propionibacterium acne bacteria can be controlled with antibacterials and plants that contain secondary metabolite compounds including flavonoids, alkaloids, saponins, steroids and tannins. One of the plants that contains secondary metabolites is calamansi orange peel. Objective: This study aims to determine the antibacterial activity of calamansi orange peel extract (Citrofortunella microcarpa Bunge) against Propionibacterium acnes bacteria through MIC and KBM testing. Method: This type of research is a true experimental method with post test only with control group design. Results: Antibacterial testing using the disc diffusion method on calamansi orange peel extract (Citrofortunella microcarpa Bunge) resulted in an inhibition zone of 22.02 mm, while MIC testing with concentrations of 5%, 7,5% and 10% resulted in inhibiting the growth of Propionibacterium acnes bacteria. while KBM did not produce results. The results of the Kruskal Wallis statistical test of 0.007 and Mann Whitney of 0.025 showed a p value <0.05, indicating that there was a significant difference between the extract concentration groups and there was a difference in the increase in the results of the bacterial activity test that received the extract treatment. Conclusion: Calamansi orange peel extract (Citrofortunella microcarpa Bunge) against Propionibacterium acnes bacteria has inhibitory power at concentrations of 50%, 75% and 100% but does not have killing power.  
Co-Authors Dede Mahdiyah, Dede Habibah, Nor Ma'rifah, Nurul Mia Audina, Mia Nastiti, Kunti NURUL HIDAYAH Putri Vidiasari Darsono, Putri Vidiasari